The Science Behind Glycyrrhizin
Glycyrrhizin, or glycyrrhizic acid, is the active chemical compound derived from the root of the Glycyrrhiza glabra plant, more commonly known as licorice. This triterpenoid compound is responsible for the distinct sweet taste of traditional black licorice, being up to 50 times sweeter than regular sucrose. Glycyrrhizin's sweetness is notable for its slower onset and lingering aftertaste compared to table sugar.
While prized for its flavor-enhancing qualities in foods, beverages, and traditional medicines for thousands of years, glycyrrhizin's physiological effects are not without risk. Once ingested, intestinal bacteria hydrolyze it into glycyrrhetinic acid. This metabolite then interferes with the enzyme 11-beta-hydroxysteroid dehydrogenase in the kidneys, which is responsible for inactivating cortisol. The resulting buildup of cortisol leads to a condition called pseudo-hyperaldosteronism, which can cause significant health problems.
Understanding the Ingredients in Liquorice Allsorts
To determine if liquorice allsorts contain glycyrrhizin, one must look at the ingredient list, which varies by manufacturer and brand. The key is to identify the presence of 'liquorice extract' or 'licorice extract'. If this is listed, it is a strong indicator that the product contains glycyrrhizin. However, not all confectionery is made with real licorice root.
Traditional Licorice-Containing Allsorts
Many classic liquorice allsorts, especially those manufactured in Europe and by traditional confectioners, feature licorice extract prominently. For example, some brands list ingredients like 'Liquorice Extract' alongside sugar, glucose syrup, and flour. The black pieces within the allsorts mix are the most likely to contain the highest concentration of this extract.
Artificially Flavored "Licorice"
In contrast, many sweets that mimic the licorice flavor, including some candies marketed as allsorts, may use an alternative flavoring agent called anise oil. Anise oil provides a similar taste but does not contain any glycyrrhizin. The red, pink, and other non-black varieties often rely on fruit or artificial flavors rather than licorice extract. This is an important distinction for consumers, especially those with health concerns related to glycyrrhizin.
The Health Risks of Glycyrrhizin
Excessive consumption of glycyrrhizin has been linked to a number of adverse health effects, primarily due to its impact on electrolyte balance and blood pressure. The most concerning health risks include:
- High Blood Pressure (Hypertension): The increase in cortisol levels caused by glycyrrhizin can lead to water and sodium retention, which elevates blood pressure. For individuals already managing hypertension, this effect can be particularly dangerous.
- Low Potassium (Hypokalemia): Glycyrrhizin's effect on the kidneys also leads to an excessive loss of potassium. Symptoms of hypokalemia can include muscle weakness, lethargy, and abnormal heart rhythms.
- Cardiac Issues: In severe or extreme cases, the combination of hypertension and low potassium can lead to serious cardiac events, including irregular heartbeat and even cardiac arrest.
- Drug Interactions: Glycyrrhizin can also interact with certain medications, such as diuretics and corticosteroids, potentially altering their effectiveness.
Regulatory bodies, such as the FDA, classify glycyrrhizin as "generally recognized as safe" as a flavoring agent, but this is within specified amounts and regular intake should be considered carefully. There is a great individual variation in susceptibility, with some people experiencing adverse effects from relatively low doses.
Comparison: Traditional Glycyrrhizin-Based vs. Artificial Flavoring
| Feature | Traditional Black Licorice (with Glycyrrhizin) | Artificially Flavored 'Licorice' (e.g., Red) | 
|---|---|---|
| Source of Flavor | Licorice root extract (Glycyrrhiza glabra) | Anise oil, fruit flavors, or other artificial flavors | 
| Glycyrrhizin Content | Present, often varies from 1% to 12% by weight | None | 
| Associated Health Risks | Potential for high blood pressure, low potassium, and cardiac issues with excessive intake | Generally considered less risky from a glycyrrhizin perspective, but still high in sugar | 
| Color Source | Black coloration derived from the natural licorice extract and other additives | Artificial colorings | 
| Common Examples | Traditional black licorice pieces in allsorts, some herbal teas | Red licorice twists, fruity-flavored jelly candies | 
Moderation and Label Awareness
For those who enjoy liquorice allsorts or other licorice-flavored products, moderation is key. Being aware of the risks associated with glycyrrhizin can help you make informed choices about your diet. Reading product labels is essential to confirm whether you are consuming real licorice extract or an anise-flavored imitation. Some brands even offer deglycyrrhizinated licorice (DGL), which has had the glycyrrhizin removed for medicinal purposes, though this is less common in standard confectionery.
For a deeper understanding of the compound, the National Institutes of Health provides excellent resources on the effects of glycyrrhizin and licorice root.(https://www.nccih.nih.gov/health/licorice-root)
Conclusion
In summary, whether liquorice allsorts contain glycyrrhizin depends entirely on the specific brand and its ingredients. If 'licorice extract' is listed on the label, then the product contains glycyrrhizin, which is present in the black-colored pieces. While generally safe in small amounts for most people, excessive and prolonged consumption carries risks, particularly for those with pre-existing conditions like hypertension or heart disease. The potential for serious side effects underscores the importance of mindful consumption and label-reading. When in doubt, or if you have health concerns, opting for artificially flavored varieties or consulting a healthcare professional is always the best course of action.