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Does Cacao Have Cannabinoids? Exploring the 'Bliss Molecule' Anandamide

4 min read

In 1996, researchers identified a cannabinoid neurotransmitter called anandamide in chocolate. This discovery sparked widespread public curiosity, with many people wondering, does cacao have cannabinoids and what is its true impact on our bodies? The answer is more nuanced than a simple yes or no, involving a deeper look at our body's own endocannabinoid system.

Quick Summary

Cacao contains small amounts of the endocannabinoid anandamide, the 'bliss molecule', and compounds that inhibit its breakdown, prolonging its effects on mood. Unlike cannabis, cacao does not contain psychoactive THC but interacts with the body's endocannabinoid system in unique, non-intoxicating ways.

Key Points

  • Endocannabinoids vs. Phytocannabinoids: Cacao contains the body's own endocannabinoid, anandamide, not the phytocannabinoids (like THC) found in cannabis.

  • Prolonged 'Bliss' Effect: Cacao contains compounds (LEA and OEA) that inhibit the breakdown of anandamide, extending its mood-boosting effects.

  • Non-Psychoactive: Unlike cannabis, cacao does not produce an intoxicating 'high' but contributes to feelings of well-being through its interaction with the ECS.

  • Synergistic Compounds: Cacao's feel-good effects are enhanced by other compounds like theobromine, PEA, and flavanols that boost mood and brain function.

  • Quality Matters: The benefits are most potent in high-cacao, minimally processed products like dark chocolate, cacao powder, or ceremonial-grade cacao.

  • Indirect ECS Booster: Cacao indirectly supports the endocannabinoid system by protecting existing anandamide, rather than directly binding to receptors like cannabis.

In This Article

Understanding the Endocannabinoid System

Before delving into cacao's specific compounds, it's crucial to understand the body's endocannabinoid system (ECS). The ECS is a complex cell-signaling system that plays a key role in regulating a wide range of functions and processes, including mood, memory, appetite, and pain sensation. It consists of three parts:

  • Endocannabinoids: These are internally produced cannabinoid-like molecules. The most famous is anandamide, derived from the Sanskrit word for 'bliss,' which is produced in the brain and plays a role in feelings of well-being.
  • Cannabinoid Receptors: These receptors (primarily CB1 and CB2) are found throughout the central and peripheral nervous systems. Endocannabinoids bind to them to signal that the ECS needs to act.
  • Enzymes: These are responsible for breaking down endocannabinoids once they have served their purpose.

Cacao and its Interaction with the ECS

The central question, does cacao have cannabinoids, gets its complex answer from the fact that while the cacao plant itself does not produce phytocannabinoids like cannabis, it contains a chemical compound that is a naturally occurring endocannabinoid in humans.

The Role of Anandamide

Cacao contains trace amounts of anandamide, the same 'bliss molecule' found in our bodies. This is a key distinction from cannabis, which contains phytocannabinoids like THC and CBD that are external to the body and interact with the ECS differently. When you consume cacao, you are not introducing a high concentration of an external cannabinoid, but rather supplementing a naturally occurring one.

Inhibiting the Breakdown of Anandamide

Perhaps more significant than the small amount of anandamide in cacao are two other compounds it contains: N-linoleoylethanolamide (LEA) and N-oleoylethanolamide (OEA). These compounds inhibit the enzyme fatty acid amide hydrolase (FAAH), which is responsible for breaking down anandamide in the body. By blocking this enzyme, cacao effectively helps to preserve and prolong the effects of the anandamide already present in your system, contributing to a longer-lasting feeling of well-being.

Other Mood-Enhancing Compounds in Cacao

Cacao’s mood-boosting effects are not solely dependent on its interaction with the ECS. It is a rich source of other compounds that influence brain chemistry:

  • Theobromine: A mild stimulant and vasodilator that can provide a gentle energy lift and improve mood.
  • Phenylethylamine (PEA): Sometimes called the 'love drug', this neuromodulator is associated with feelings of excitement and pleasure, similar to those experienced when falling in love.
  • Tryptophan: An amino acid and precursor to the neurotransmitter serotonin, which is crucial for regulating mood and happiness.
  • Flavanols: These antioxidants improve blood flow to the brain, which can enhance cognitive function and protect against neurodegenerative diseases.

Cacao vs. Cannabis: ECS Interaction Compared

To clarify the difference, consider the following comparison of how cacao and cannabis affect the endocannabinoid system:

Feature Cacao Cannabis (Marijuana)
Primary Cannabinoids Contains trace amounts of the endocannabinoid anandamide and compounds (LEA, OEA) that inhibit its breakdown. Contains high levels of phytocannabinoids like THC (psychoactive) and CBD (non-psychoactive).
ECS Interaction Indirectly boosts ECS activity by preventing the degradation of your body's own anandamide, prolonging its effects. Directly binds to CB1 and CB2 receptors, triggering effects in a manner that mimics or replaces the body's natural cannabinoids.
Psychoactive Effects Non-psychoactive. Effects are subtle mood enhancement, energy, and well-being. Psychoactive with THC, causing intoxication, altered perception, and other well-known effects.
Overall Effect Gentle, sustained mood lift and potential cognitive benefits. Potent, direct, and often intense psychoactive and physiological effects.

Choosing the Right Cacao for Maximum Benefits

The health benefits of cacao, particularly its interaction with the ECS, are most prominent in high-quality, minimally processed forms. The key is maximizing the concentration of beneficial compounds while minimizing unnecessary additions like sugar and milk fat.

Here are some tips for selecting cacao products:

  • Opt for high-cacao content dark chocolate (70%+): The higher the percentage, the more concentrated the beneficial flavanols and other compounds. Be mindful of added sugars.
  • Choose cacao powder over cocoa powder: Cacao powder is made from raw, cold-pressed beans, retaining more of the original nutrients. Cocoa powder is processed with heat, which can reduce its flavanol content.
  • Consider ceremonial-grade cacao: This minimally processed paste from whole fermented cacao beans is ideal for those seeking the maximum therapeutic effect, often used in ancient rituals for its consciousness-expanding properties.
  • Avoid highly processed milk chocolate: The high sugar content and low cacao concentration negate most of the health benefits.

Conclusion: The Final Word on Cacao and Cannabinoids

So, does cacao have cannabinoids? The answer is yes, but with a critical distinction. Cacao contains the endocannabinoid anandamide, a molecule our bodies naturally produce. More importantly, it possesses unique compounds that protect and prolong the effects of this 'bliss molecule' within our system. Unlike the phytocannabinoids found in cannabis, cacao does not induce intoxication. Instead, its blend of anandamide, theobromine, PEA, and flavanols works synergistically with the body's endocannabinoid system to provide a gentle, non-psychoactive mood lift and cognitive boost. This scientific understanding explains why consuming high-quality cacao can contribute to a natural sense of happiness and well-being, solidifying its reputation as a 'food of the gods.'

For a deeper dive into the endocannabinoid system, a foundational review can be found here: An introduction to the endogenous cannabinoid system.

Frequently Asked Questions

No, you cannot get high from eating cacao. It does not contain THC, the psychoactive compound found in cannabis. Cacao's interaction with your body's endocannabinoid system is gentle and non-intoxicating.

Anandamide is not the same as THC. Anandamide is an endocannabinoid, meaning it's produced naturally by the body, whereas THC is a phytocannabinoid that comes from the cannabis plant. While both interact with cannabinoid receptors, their effects are very different.

The 'bliss molecule' is anandamide, an endocannabinoid named after the Sanskrit word for 'bliss.' It is a neurotransmitter involved in mood and pleasure and is found in trace amounts in cacao.

Cacao affects your mood by containing trace amounts of anandamide and compounds that prevent its rapid breakdown. It also contains other mood-boosting chemicals like theobromine and phenylethylamine, which promote feelings of well-being and pleasure.

No, not all chocolate offers the same benefits. The highest concentration of beneficial compounds is found in high-cacao content products like dark chocolate (70%+) and minimally processed cacao powder. Highly processed milk and white chocolate have very little cacao.

Some sources suggest that cacao can enhance the effects of cannabis due to its compounds inhibiting the breakdown of anandamide, which has a similar structure to THC. This may increase the longevity and intensity of effects. However, this should be approached with caution and is not a replacement for professional medical advice.

Yes, several other plants produce cannabinoids, though they are generally different from those found in cannabis. Examples include echinacea, which produces compounds that interact with the CB2 receptor, and certain types of liverwort.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.