Does Costco Have NAD Supplements? What You Need to Know

October 4, 2025 •

4 min read

Research indicates that NAD+ levels decline by more than 50% between the ages of 40 and 60, prompting many to seek supplementation to boost their levels. This has led to the common question: Does Costco have NAD supplements? The answer is nuanced, as while you won't typically find direct NAD+ supplements in-store or online, Costco does carry effective NAD+ precursors like Nicotinamide Mononucleotide (NMN).

Quick Summary

Costco primarily sells NMN supplements, a highly bioavailable precursor that the body converts into NAD+, rather than offering direct NAD+ supplements. This provides a practical way to support cellular health, energy metabolism, and DNA repair by restoring declining NAD+ levels that occur with aging.

Key Points

Availability at Costco: Costco does not carry direct NAD+ supplements but does offer NMN, a highly bioavailable precursor.
NMN is an Effective Precursor: Because direct NAD+ is poorly absorbed orally, NMN is a more practical and effective way to increase cellular NAD+ levels.
Benefits of Supplementation: Boosting NAD+ through NMN can improve cellular energy, metabolism, DNA repair, and overall anti-aging pathways.
Check for Quality: When purchasing NMN, verify its purity and potency by looking for third-party testing and a Certificate of Analysis (COA).
Mild Side Effects: NMN is generally safe, but some users may experience mild and transient side effects, such as digestive discomfort, headaches, or fatigue.
Webber Naturals NMN: At least in some regions, Costco offers specific NMN products, such as the Webber Naturals NMN exclusive to its stores in Canada.

Understanding the Difference: NAD+, NMN, and Costco's Offerings

Many consumers searching for ways to combat the effects of aging and boost cellular energy have heard about Nicotinamide Adenine Dinucleotide (NAD+) and its role in metabolic processes. However, the supplement landscape can be confusing, especially regarding what major retailers like Costco offer. It's crucial to understand the distinction between NAD+ itself and its precursor, NMN.

NAD+ is a vital coenzyme found in every cell of your body, where it plays a key role in over 500 enzymatic reactions, including converting food into energy and repairing DNA. As a molecule, however, NAD+ is too large and unstable to be effectively absorbed by the body through oral supplementation.

This is where Nicotinamide Mononucleotide (NMN) comes in. NMN is a smaller, more bioavailable molecule that acts as a direct precursor to NAD+. Your body can efficiently absorb NMN and then convert it into NAD+ inside your cells through a natural enzymatic process. This makes NMN the more effective oral supplement for boosting NAD+ levels. While direct NAD+ infusions are available in clinical settings, NMN provides a convenient at-home option.

Costco's NMN Availability

Costco, known for its extensive range of supplements, follows the market trend by offering NMN products rather than the less effective oral NAD+ versions. Availability can vary by country and region, but products like Webber Naturals NMN have been identified as exclusive to Costco in some locations, such as Canada. The company's online supplement section and in-store pharmacies are the best places to check for current stock. Given the high demand for longevity supplements, products may be out of stock, so checking the online store regularly is recommended.

Benefits of Boosting NAD+ via NMN

Restoring healthy NAD+ levels through NMN supplementation has been associated with several potential health benefits, especially as a strategy for healthy aging. These include:

Enhanced Energy Metabolism: NAD+ is critical for mitochondrial function, helping to turn food into usable energy and potentially improving energy levels.
Improved Brain Function: Research in animal models and limited human studies suggests NMN supplementation can support cognitive health, memory, and neuronal protection.
Support for Cellular Repair: NAD+ fuels sirtuin proteins and PARPs, which are involved in repairing DNA damage that accumulates over time.
Cardiovascular Health: Some evidence suggests that boosting NAD+ levels can support heart and blood vessel health by protecting against oxidative damage.
Muscle Function and Performance: Studies have shown NMN supplementation can improve aerobic capacity and muscle strength, particularly in older adults and athletes.

Factors to Consider When Buying NMN

When purchasing NMN supplements, especially from a large retailer like Costco, several factors should influence your decision:

Product Purity and Third-Party Testing: The supplement industry is not heavily regulated, making quality control a major concern. It is essential to look for brands that provide a Certificate of Analysis (COA) from an independent, third-party lab to verify the purity, potency, and absence of contaminants. While Kirkland Signature products are known for their quality control, this is a key consideration for any brand.
Dosage and Formulation: Clinical studies have tested a wide range of NMN dosages. Look for a product with a clearly stated dosage that aligns with your research or healthcare provider's recommendations. Common forms include capsules, powders, and sublingual options.
Ingredients: Always check the ingredients list for potential allergens or undesirable fillers. High-quality NMN supplements should primarily contain NMN with minimal other additives.

Comparison Table: NAD+ vs. NMN


Feature	NAD+ (Direct Supplementation)	NMN (Precursor Supplementation)
Molecular Role	A coenzyme used directly by cells for energy and repair.	A precursor molecule that helps the body synthesize NAD+.
Oral Absorption	Poor oral bioavailability due to large size and instability.	Superior oral absorption; easily taken up by the gut and converted.
Typical Delivery	Primarily through IV therapy in clinical settings.	Widely available in convenient oral forms like capsules and powders.
Cost	Typically more expensive, especially for IV treatments.	Generally more affordable and accessible for daily supplementation.
Availability at Costco	Not available.	Available in various brands, like Webber Naturals.

Potential Side Effects

NMN is generally considered safe and well-tolerated, with human studies showing no serious adverse effects at common dosages. Some individuals may experience mild side effects, particularly when starting supplementation, such as:

Mild digestive issues
Headaches
Temporary fatigue

These symptoms typically resolve as the body adjusts. It's always best to consult with a healthcare provider before starting any new supplement regimen to ensure it is appropriate for your individual health needs.

Conclusion: Finding the Right Supplement

While the direct answer to "Does Costco have NAD supplements?" is no, the deeper understanding of the science reveals why. NMN supplements, which Costco does offer, provide a more practical and bioavailable method for restoring declining NAD+ levels that accompany aging. For those interested in supporting their cellular energy, metabolism, and overall vitality, exploring Costco's selection of high-quality NMN products can be a valuable starting point. Always prioritize third-party tested supplements and consult with a healthcare professional before beginning any new regimen to ensure safety and effectiveness. By choosing the right precursor, you can provide your body with the tools it needs to support its natural cellular processes and promote healthy aging from within.

Frequently Asked Questions

No, Costco does not typically sell direct NAD+ supplements because the molecule is poorly absorbed when taken orally. Instead, they offer NMN (Nicotinamide Mononucleotide), which is a highly effective and absorbable precursor that the body converts into NAD+.

NMN is sold instead of NAD+ because it is a smaller, more stable, and more bioavailable molecule. This means it can be absorbed by the body through oral supplementation and efficiently converted into the vital NAD+ coenzyme inside your cells.

NMN, or Nicotinamide Mononucleotide, is a naturally occurring compound that serves as a building block for NAD+. When you take NMN, your body quickly absorbs it and uses it to synthesize NAD+, which then helps power critical cellular functions like energy production and DNA repair.

NMN supplements, by boosting NAD+ levels, may offer several benefits. These include improved energy metabolism, enhanced brain and cardiovascular health, better muscle function, and support for cellular repair to combat signs of aging.

NMN is generally considered safe, but some people might experience mild side effects, such as headaches, temporary fatigue, or digestive discomfort. These effects often subside as your body adjusts to the supplement.

To ensure quality, look for NMN products that are independently tested. While Costco's house brand Kirkland Signature has strong quality controls, always check the label for independent certifications (like NSF or USP) or for a brand that provides a Certificate of Analysis (COA).

When purchasing NMN, look for third-party testing to verify purity and potency. You should also consider the dosage, the formulation (capsule, powder, etc.), and check the ingredients list for any potential allergens or fillers.