Skip to content

Does Magnesium Cream Get Into Your Bloodstream? The Science of Topical Absorption

4 min read

According to a 2017 pilot study, applying magnesium cream led to a clinically relevant increase in serum magnesium levels in non-athletes, suggesting that topical delivery can indeed lead to systemic absorption. So, does magnesium cream get into your bloodstream? The answer, supported by increasing research, is yes, though the degree of absorption and overall efficacy compared to oral supplements are still subjects of scientific investigation.

Quick Summary

Topical magnesium, including creams and oils, can be absorbed through the skin and enter the bloodstream, bypassing the digestive system. Absorption is influenced by factors like skin condition, concentration, and application technique. Studies show it can increase magnesium levels, providing potential benefits for muscle function and recovery.

Key Points

  • Systemic Absorption: Studies indicate that magnesium cream can be absorbed through the skin and enter the bloodstream, though the degree of absorption can vary.

  • Bypasses Digestion: Applying magnesium topically allows it to bypass the digestive system, making it an excellent alternative for individuals who experience gastrointestinal side effects from oral supplements.

  • Targeted Relief: Topical magnesium is particularly useful for targeted application to sore muscles or areas of tension, offering localized relief and aiding in muscle recovery for athletes.

  • Multiple Factors Influence Absorption: The effectiveness of topical magnesium absorption is influenced by factors such as skin hydration, product concentration, the area of application, and massage technique.

  • Evidence is Emerging: While promising, research on transdermal magnesium is still developing, and more large-scale studies are needed to confirm the long-term effects and compare its efficacy definitively against oral supplements.

  • Complementary, Not Replacement: Topical magnesium is best used as a complement to, rather than a replacement for, a magnesium-rich diet. A balanced nutritional plan is essential for overall magnesium status.

In This Article

The Mechanism of Transdermal Magnesium Absorption

For an external substance like magnesium to enter the bloodstream through the skin, it must first navigate the skin's various layers. The skin's outermost layer, the stratum corneum, acts as a primary barrier. However, magnesium ions are able to permeate this layer through specific pathways, such as sweat glands and hair follicles.

Once past the stratum corneum, the magnesium ions enter the epidermis and then the dermis, where blood vessels are located. This process is driven by diffusion, where the ions move from an area of high concentration (the cream on the skin) to an area of lower concentration (the body's tissues and bloodstream). This absorption route bypasses the gastrointestinal tract, which is a key advantage for individuals who experience digestive issues or poor absorption with oral supplements.

Factors Influencing Topical Magnesium Absorption

Several variables can affect how well magnesium cream is absorbed into the bloodstream and tissues. By optimizing these factors, users may enhance the benefits of topical application.

  • Skin Condition: Healthy, well-hydrated skin is generally more permeable and absorbs magnesium more efficiently than dry or damaged skin.
  • Product Concentration: The concentration of magnesium in the cream can significantly impact the rate and amount of absorption. Higher concentrations are often associated with better uptake.
  • Application Area: Applying the cream to areas with thinner skin or a higher density of hair follicles and sweat glands, such as the scalp or armpits, may result in greater absorption.
  • Duration and Frequency: The longer the magnesium product is left on the skin, and the more consistently it's applied, the greater the potential for absorption.
  • Temperature: Warm skin, such as after a bath or shower, can increase circulation and open pores, potentially boosting absorption.
  • Massage: Gently massaging the cream into the skin can help improve blood circulation in the area, further enhancing the absorption process.

Topical vs. Oral Magnesium: A Comparison

For those considering magnesium supplementation, understanding the differences between topical and oral delivery methods is crucial. Each has distinct advantages and potential drawbacks, as shown below.

Feature Topical Magnesium (Creams, Oils) Oral Magnesium (Pills, Powder)
Absorption Route Through the skin, bypassing the digestive system. Through the gastrointestinal tract and intestinal lining.
Bypasses Digestion Yes, excellent for those with GI issues or poor absorption. No, can cause laxative effects or stomach upset in some people, especially at high doses.
Absorption Rate Studies suggest faster absorption into tissues, though large-scale systemic absorption is debated. Variable absorption rates depending on the form of magnesium (e.g., citrate, oxide).
Dosage Control Easier to adjust dose based on application area and frequency. Fixed dose per capsule/tablet; requires monitoring intake and potential side effects.
Targeted Relief Yes, allows for direct application to sore muscles or areas of tension. No, provides systemic absorption to address overall deficiency, not localized issues.

Scientific Evidence and Research

While anecdotal evidence and manufacturer claims about topical magnesium are abundant, a growing body of research is exploring the science behind it. In-vitro studies confirm that magnesium can penetrate the skin's layers, with absorption being influenced by concentration and exposure time.

One frequently cited pilot study from 2017 investigated the effects of a magnesium cream on serum and urinary magnesium levels in a small group of human participants. While overall results were not statistically significant, a subgroup of non-athletes showed a statistically significant and clinically relevant increase in serum magnesium levels after two weeks of use. The study's authors suggested that higher concentrations and longer durations might be needed to see more conclusive results across all participants.

Other studies point to transdermal magnesium providing benefits for specific conditions. Research on fibromyalgia patients found that applying magnesium oil to the limbs showed significant reductions in symptoms over a four-week period. For athletes, topical magnesium is praised for its ability to provide targeted relief for muscle cramps and soreness, speeding up recovery and reducing inflammation.

Despite these promising findings, some scientific reviews argue that the evidence is currently insufficient to support claims of superior absorption compared to oral supplements. Most studies have been small-scale pilot trials, and more large, robust, and randomized controlled trials are needed to draw definitive conclusions.

A Complement to Your Nutritional Strategy

Ultimately, topical magnesium cream should be viewed as a complementary tool within a broader nutritional strategy, not a complete replacement for dietary sources. A balanced nutrition plan, rich in magnesium-containing foods like leafy greens, nuts, seeds, and whole grains, remains the cornerstone of maintaining adequate magnesium levels.

For those seeking targeted relief for muscle soreness, addressing digestive intolerance, or simply looking for an alternative route of supplementation, magnesium cream can be a valuable option. Consistent and correct application, coupled with a healthy diet, can offer potential benefits for muscle recovery, relaxation, and overall well-being. As with any supplement, it is always wise to consult with a healthcare professional to determine if topical magnesium is the right choice for your individual needs and to discuss any underlying health conditions.

Healthline offers further information on various magnesium types and their benefits: Types of Magnesium and Their Benefits.

Frequently Asked Questions

Magnesium ions from the cream penetrate the skin, primarily through sweat glands and hair follicles, moving from a higher concentration area on the skin to a lower concentration area within the body's tissues and eventually into the bloodstream via tiny blood vessels.

Topical application bypasses the digestive system, which can be advantageous for individuals with poor gastrointestinal absorption or those who experience stomach upset from oral supplements. However, the overall effectiveness and degree of systemic absorption compared to oral forms are still subjects of scientific debate, and more robust research is needed.

While magnesium cream can contribute to your overall magnesium status, it should not be the sole source. A balanced diet rich in magnesium-containing foods remains the primary method for maintaining healthy levels. The cream is best used as a supplement or for targeted relief.

Potential benefits include relieving muscle soreness and cramps, promoting muscle relaxation, reducing stress, improving sleep quality, and hydrating the skin. It can be particularly beneficial for athletes or individuals with localized muscle tension.

Topical magnesium is generally considered safe. Some individuals, particularly those with sensitive skin, may experience a mild tingling or itching sensation, especially with more concentrated products like magnesium oil. Diluting the product or using a lower concentration cream can help mitigate this.

Frequency depends on the individual and the product's concentration. Consistent, daily application is often recommended for optimal results, especially for muscle recovery or relaxation. Applying it after a warm bath or shower can also enhance absorption.

Magnesium is known to help regulate the nervous system, which can reduce stress and promote relaxation. While more research is needed specifically on the topical application for these benefits, many users report improved sleep and reduced anxiety when applying magnesium cream before bed.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7
  8. 8

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.