The Science of Umami and Salivation
The phenomenon of a mouthwatering response to monosodium glutamate (MSG) is directly tied to the science of taste perception. MSG is the purest form of umami, often described as a savory, meaty, or broth-like flavor. When MSG is consumed, its key component, L-glutamate, activates specific taste receptors on the tongue. These receptors, known as T1R1/T1R3 and certain metabotropic glutamate receptors (mGluRs), are responsible for detecting umami. The activation of these receptors triggers the gustatory-salivary reflex, signaling the brain to increase the production and flow of saliva.
This increased salivation is not just a passive response; it serves a crucial purpose. Saliva helps dissolve flavor compounds in food, allowing them to reach the taste buds more effectively. It also lubricates the food, preparing it for swallowing and aiding in digestion. This entire process—from tasting umami to increased salivation—enhances our perception of flavor and makes the food more palatable and enjoyable.
Umami and the Mouthfeel Phenomenon
Beyond simply creating a savory taste, umami contributes to a complex sensory experience known as "mouthfeel." This sensation, referred to as "kokumi" in Japanese, is characterized by attributes like richness, thickness, and a lingering, mouth-filling quality. The savory, mouthwatering effect of umami is a major contributor to this perception. Studies show that MSG can enhance these kokumi attributes, making foods feel more substantial and satisfying.
This effect is not just a direct result of MSG alone. MSG also interacts synergistically with other naturally occurring umami compounds in food, such as inosinate (found in meat) and guanylate (found in mushrooms), to amplify the mouthfeel and flavor. This synergy creates a deeper, more rounded flavor profile, which explains why a dish with umami-rich ingredients often tastes more complex than the sum of its parts.
Comparison of Flavor Enhancers: MSG vs. Natural Umami Sources
| Feature | Monosodium Glutamate (MSG) | Natural Umami Sources (e.g., Aged Cheese, Tomatoes) | 
|---|---|---|
| Form | A pure, crystalline powder. | A component naturally found within whole foods. | 
| Mechanism | The free L-glutamate binds directly to umami receptors. | Free glutamate is released from proteins during fermentation, aging, or cooking. | 
| Sodium Content | Contains about one-third the sodium of table salt. | Varies significantly depending on the food. | 
| Flavor Impact | Provides a strong, concentrated umami boost. | Offers a more subtle, integrated umami flavor. | 
| Synergy | Highly synergistic with other umami nucleotides (inosinate, guanylate). | Often contains a natural mix of umami compounds, leading to inherent synergy. | 
Debunking the Myths: MSG and Health
For decades, MSG was stigmatized by the notion of "Chinese Restaurant Syndrome," a misconception that arose from an anecdotal letter in 1968. However, decades of scientific research, including controlled studies with individuals who self-report MSG sensitivity, have failed to find a consistent link between MSG and the reported symptoms. Regulatory bodies worldwide, including the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA), classify MSG as generally recognized as safe (GRAS).
It's important to differentiate between MSG's natural function and its perception based on a long-standing myth. At typical dietary consumption levels, MSG's effect on salivation and flavor enhancement is a normal physiological response to the umami taste, not a sign of an adverse reaction.
Using Umami for Healthier Diets
The umami taste provided by MSG and other sources can be a valuable tool for modern nutrition, particularly in creating healthier food options. Research shows that umami can be used to improve the flavor of foods with reduced sodium or fat content. Since MSG has less sodium than table salt, it can help lower overall sodium intake while maintaining a satisfying flavor profile. This can be particularly beneficial for populations at risk of hypertension.
Furthermore, for elderly individuals or patients experiencing a decline in their sense of taste and smell, umami can improve the palatability of meals, thereby encouraging better food consumption and overall nutritional status. The added enjoyment can prevent malnutrition and improve quality of life.
Conclusion
In summary, the answer to the question, "Does MSG make your mouth water?" is a definitive yes, and it is a scientifically understood aspect of the umami taste. The activation of glutamate receptors on the tongue triggers a natural salivary response that, in turn, enhances the perception of flavor. This mouth-watering effect, alongside the contributions to mouthfeel, is why MSG and other umami-rich foods are so satisfying. Far from being a harmful substance, MSG is a safe and effective tool that can be used to improve the palatability of healthy foods, reduce reliance on excess salt, and enhance the dining experience for various populations.
For further reading on the flavor-enhancing action and safety of glutamate, consult this comprehensive review.