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Does the 1:1 Diet Put You in Ketosis for Weight Loss?

4 min read

According to research and official information from the brand, most people following the initial steps of the 1:1 Diet (formerly the Cambridge Diet) do go into a state of ketosis. This metabolic state, triggered by a very low-calorie and reduced-carbohydrate intake, causes the body to burn fat for fuel instead of glucose.

Quick Summary

The 1:1 Diet's very low-calorie meal replacements typically induce ketosis, prompting the body to burn fat for energy. This approach is similar to, but distinct from, a traditional keto diet, and it leverages the appetite-suppressing effects of ketones for weight management.

Key Points

  • Ketosis on the 1:1 Diet: The very low-calorie intake of the initial 1:1 Diet steps forces the body into ketosis, burning fat for energy.

  • Low Calorie, Not Just Low Carb: Unlike a traditional keto diet, the 1:1 Diet uses extreme calorie restriction to induce ketosis, even with a moderate amount of carbohydrates.

  • Meal Replacement Formulas: The diet relies on nutritionally complete meal replacements, rather than whole foods, to control calorie and macronutrient intake.

  • Potential for Side Effects: As the body adjusts to ketosis and low calories, side effects like 'keto flu,' constipation, and bad breath may occur.

  • Professional Guidance is Key: A unique feature of the 1:1 Diet is the one-on-one consultant support, which is recommended for managing health and avoiding complications.

  • Not for Long-Term Maintenance: The intensive phases are designed for rapid, short-term weight loss and are not intended for long-term, sustainable habits.

In This Article

The 1:1 Diet, which evolved from the Cambridge Weight Plan, uses a highly structured program of low-calorie meal replacements to trigger rapid weight loss. At the core of its initial phases, the diet significantly reduces calorie and carbohydrate intake, forcing the body into a metabolic state called ketosis. While this sounds like the popular keto diet, there are key differences in the approach, structure, and overall nutritional strategy.

The Science of Ketosis on a Low-Calorie Diet

Ketosis is a natural metabolic process where the body, lacking sufficient glucose from carbohydrates, begins to burn stored fat for energy instead. The liver breaks down fat into compounds called ketones, which then become the body's primary fuel source. This can occur through prolonged fasting or, more commonly, by following a very low-carbohydrate or very low-calorie diet.

The 1:1 Diet's initial steps are designed specifically to bring about this metabolic shift. By replacing all or most regular meals with nutritionally complete, but very low-calorie, formula products like shakes, soups, and bars, the body's glucose reserves are quickly depleted. This calorie restriction, often below 800 kcal per day in the most intensive stages, is what prompts the liver to ramp up ketone production. The resulting state of ketosis can lead to a reduced appetite, which can be a major advantage for dieters.

How Carbohydrate Restriction Affects Ketosis

Many people assume that to achieve ketosis, carbohydrate intake must be extremely low, often less than 50 grams per day. While this is the foundation of a traditional ketogenic diet, research supported by the 1:1 Diet's developers shows that a very low-calorie intake can also induce ketosis, even with a slightly higher carbohydrate load. This is because the overall energy deficit forces the body to turn to alternative fuel sources, regardless of whether carbohydrate consumption is at a strict keto-level.

The 1:1 Diet vs. a Traditional Ketogenic Diet

While both diets leverage ketosis for weight loss, their methods and compositions are fundamentally different. A traditional keto diet relies on a high intake of dietary fats, moderate protein, and very low carbohydrates. The 1:1 Diet, conversely, is a meal replacement-based, very low-calorie diet with a different macronutrient ratio.

Comparison Table: 1:1 Diet vs. Traditional Keto

Feature 1:1 Diet (Intensive Steps) Traditional Ketogenic Diet
Method Uses formula-based meal replacements to create a very low-calorie diet. Emphasizes whole, low-carb foods high in fats (e.g., meat, oils, nuts) and restricts carbs.
Calorie Intake Typically less than 800 kcal per day in the initial phases. Normocaloric, or restricted based on individual goals, with focus on macronutrient ratios.
Ketosis Induction Achieved through severe calorie restriction, even with moderate carbs. Achieved by drastically limiting carbohydrate intake to <50g per day.
Nutritional Composition Precisely balanced formula products ensure micronutrient needs are met. Requires careful meal planning to avoid nutrient deficiencies due to eliminated food groups.
Support System Provides personalized, one-to-one support from a dedicated consultant. Often followed independently or through online communities; requires self-education.
Carb Source Contains some carbohydrates in the formulas, specifically formulated to prevent excessive ketosis. Severely restricts carbs, eliminating grains, most fruits, and starchy vegetables.

Risks and Side Effects of Ketosis and VLCDs

While ketosis can be an effective weight-loss tool, especially with appetite suppression, it's not without potential side effects, particularly when induced by a very low-calorie diet. These effects are often temporary as the body adjusts, but they require careful management.

  • Keto Flu: Many people experience flu-like symptoms like headaches, fatigue, and nausea as their body transitions to using ketones for fuel.
  • Constipation: Low fiber intake from restricted foods can cause digestive issues. The 1:1 Diet recommends fiber supplements to combat this.
  • Dehydration and Electrolyte Imbalances: Increased urination is common in the initial phase of ketosis, which can lead to dehydration and electrolyte loss. High fluid intake is essential.
  • Bad Breath: The production of the ketone body acetone can cause a distinct, fruity odor on the breath.
  • Nutrient Deficiencies: Although the 1:1 Diet formulas are fortified, extreme dietary restriction can pose a risk for long-term deficiencies if not managed properly.

Due to these potential side effects and the diet's restrictive nature, it is crucial to follow the 1:1 Diet under the supervision of a consultant and potentially a medical professional.

Conclusion

The answer is a definitive yes: the 1:1 Diet does put you in ketosis, particularly during its intensive, very low-calorie initial phases. The significant calorie and carb reduction forces the body into this fat-burning metabolic state, which can help suppress appetite and accelerate weight loss. However, it is fundamentally different from a standard ketogenic diet. The 1:1 Diet uses structured meal replacement formulas and professional guidance, offering a nutritionally complete but calorie-restricted approach. A traditional keto diet, by contrast, focuses on macronutrient ratios from whole foods with no formal consultant support. While both paths can lead to ketosis, the risks and benefits of each must be weighed carefully, and expert supervision is recommended for any drastic dietary change.

Sources

Cambridge Diet™ Review - Jane Plan. (2024, June 3). Jane Plan. What You Didn’t Know about Ketogenic and Low-Carb Diets. (n.d.). One2onediet.com. What is a Keto Diet & Is it Beneficial?. (n.d.). One2onediet.com. Ketosis: Definition, Benefits & Side Effects. (n.d.). Cleveland Clinic. Ketosis: Definition, Keto Diet, Symptoms, and Side Effects. (n.d.). WebMD. 7 Potential Dangers of the Keto Diet. (2020, March 25). Healthline. What is the Cambridge diet?. (2023, August 3). BBC Good Food. The 1:1 Diet - FAQs. (n.d.). One2onediet.com. Very Low-Calorie Ketogenic Diet: A Potential Application in .... (2022, June 9). National Institutes of Health (NIH) | (.gov). Pros and Cons of the Keto Diet. (2025, February 25). Northwestern Medicine.

Frequently Asked Questions

The main difference is the method of achieving ketosis. The 1:1 Diet uses structured, very low-calorie meal replacements and has a consultant-guided process. A traditional keto diet relies on a high-fat, very low-carb whole-food approach, with no formal support structure.

No, they are two very different and distinct metabolic states. The ketosis from a diet is a controlled, physiological process, while diabetic ketoacidosis is an uncontrolled, dangerous medical condition seen in people with type 1 diabetes.

While individual results vary, many people can enter ketosis within a few days of starting the initial, very low-calorie steps of the diet.

Yes. The ketosis induced by the diet is known to have an appetite-suppressing effect, which helps to manage hunger and cravings, supporting weight loss efforts.

No, the meal replacement products used in the 1:1 Diet are nutritionally complete and formulated to provide all the vitamins and minerals you need. However, extra fluids and sometimes fiber are recommended.

Yes, common side effects can include 'keto flu' symptoms such as headaches and fatigue, as well as constipation, dehydration, and bad breath. These usually subside as your body adapts.

No, the diet is structured around its specially formulated, low-calorie meal replacement products. Following the plan without them is not the 1:1 Diet and would not replicate its specific ketogenic effect.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.