What is Glycerin?
As a simple polyol compound, glycerin (or glycerol) is a colorless, odorless, and sweet-tasting liquid. It is a versatile compound found in many products, from food and beverages to cosmetics and pharmaceuticals. Most glycerin comes from vegetable sources, such as soy, palm, or coconut oils, and is made by heating triglyceride-rich fats under pressure. Its humectant properties—the ability to attract and retain moisture—form the basis for many of its health benefits when taken orally.
Oral Glycerin for Digestive Health
Glycerin's most common use in oral supplements is as a laxative to relieve occasional constipation.
- Relieves constipation: Glycerin is a hyperosmotic laxative, which means it draws water into the intestines to soften and lubricate hardened stool, making it easier to pass. This effect, often experienced within 15 to 60 minutes after use as a suppository, provides fast and predictable relief.
- Supports regularity: For those with infrequent or difficult bowel movements, using glycerin as needed can help restore a more regular pattern.
Glycerin's Role in Hydration and Athletic Performance
For endurance athletes, maintaining proper hydration is critical for performance, and this is where glycerin offers unique benefits.
- Enhances hyperhydration: Glycerin's humectant properties mean it can help the body retain extra fluid for longer periods when consumed with water before exercise. This can be particularly useful in hot, humid conditions where high sweat losses are expected.
- Reduces fluid loss: By increasing fluid retention, glycerin can decrease the volume of urine produced, helping athletes stay hydrated for longer.
- Delays dehydration effects: A state of elevated body water can increase an athlete's capacity to tolerate fluid loss and delay the performance-reducing effects of dehydration. This may lead to small improvements in endurance performance, though results vary and some studies are older.
Other Potential Health Applications
Beyond digestion and athletic performance, medical research has explored other uses for glycerin.
- Lowers eye pressure: Oral glycerin can be used under a doctor's supervision to reduce elevated intraocular pressure, such as in cases of glaucoma. It does this by creating an osmotic gradient that pulls fluid out of the eye and into the bloodstream.
- Reduces cranial pressure: In some medical emergencies, intravenous or oral glycerin has been used to reduce increased intracranial pressure.
Potential Risks and How to Mitigate Them
While generally safe, taking glycerin orally, especially in large doses, can cause some side effects.
| Side Effect | Cause | Mitigation Strategy | 
|---|---|---|
| Headaches | Changes in blood pressure or dehydration from fluid shifts. | Lie down while taking it, or for a short time afterward. Ensure adequate hydration with plenty of water. | 
| Gastrointestinal Distress | Osmotic effects drawing too much water into the gut, leading to bloating, nausea, or diarrhea. | Start with a small dose to see how your body reacts. Avoid taking large amounts at once. | 
| Excessive Thirst | A side effect related to the osmotic process, signaling fluid movement within the body. | Ensure you are drinking sufficient water alongside the glycerin to prevent dehydration. | 
| Allergic Reaction | Although rare, contact dermatitis or a skin rash can occur. | Discontinue use immediately if you experience itching, rash, or swelling. | 
| Fluid Retention/Weight Gain | Increased water retention is a key mechanism for its hydrating effects but can lead to temporary weight gain. | Monitor your body's reaction and balance fluid intake, especially for weight-sensitive athletic performance. | 
Considerations for Oral Glycerin Use
To maximize the benefits and minimize the risks, consider these guidelines before taking glycerin:
- Follow dosage instructions: Oral glycerin is dosed based on body weight for medical purposes, so always follow a doctor's specific prescription. For general wellness, start with a low dose.
- Stay hydrated: Drinking plenty of water with oral glycerin is essential to prevent dehydration and reduce side effects like headaches.
- Consult a professional: Individuals with diabetes, kidney disease, or other medical conditions should speak with a healthcare provider before using glycerin. Glycerol was also once banned by the World Anti-Doping Agency (WADA), and athletes should verify its current status and consult a sports dietitian.
Conclusion
The benefits of taking glycerin are diverse and impactful, particularly for digestive health and athletic performance. As a powerful humectant, it effectively relieves constipation by drawing water into the intestines. For athletes, it offers a means of hyperhydration that helps the body retain fluid and delay dehydration effects during prolonged exercise in hot conditions. Beyond these uses, it has specific medical applications for managing eye and cranial pressure. However, it is crucial to use glycerin responsibly, start with low doses, and ensure proper hydration to avoid potential side effects. Always consult with a healthcare provider to determine if glycerin is right for your specific health goals and needs.
The Role of Glycerin as a Humectant
Glycerin's value comes from its nature as a humectant, a substance that attracts and holds water. This property is crucial not only for oral intake but also for its widespread use in topical skin products. As a humectant, glycerin helps moisturize the skin by drawing water to the outer layer, known as the stratum corneum, supporting the skin's barrier function and accelerating wound healing.
For additional resources on hydration and athletic nutrition, consider visiting the Australian Sports Commission's detailed information on glycerol.