How Many Billion Bacteria Are in Vivomixx? Unpacking the Potent Probiotic Count

January 2, 2026 •

3 min read

Vivomixx contains a very high concentration of bacteria, with its original sachets offering 450 billion bacteria per serving. This article answers precisely how many billion bacteria are in Vivomixx, comparing its different formats and explaining why this high potency is beneficial for your gut health.

Quick Summary

The bacterial count in Vivomixx varies by product format. Standard sachets contain 450 billion live bacteria, while standard capsules have 112 billion, all part of the De Simone Formulation.

Key Points

High Potency: Vivomixx offers different bacterial counts depending on the format, with 450 billion CFU per sachet and 112 billion CFU per capsule in its standard version.
Multiple Strains: The probiotic uses a specific, clinically researched blend of eight bacterial strains known as the De Simone Formulation.
Effective Colonization: The high concentration is crucial for ensuring effective colonization of the gut, providing a significant boost to the intestinal flora.
Requires Refrigeration: To preserve the potency of the live bacteria, Vivomixx must be stored in the refrigerator.
Historical Context: The same formulation in Vivomixx was previously sold under the brand name VSL#3, reflecting a history of extensive clinical research.
Format Differences: The primary difference between Vivomixx formats is the dosage, with sachets providing a higher dose than capsules.

The High Bacterial Count in Vivomixx

Vivomixx is known for its high concentration of live bacteria, significantly more than many other probiotic supplements. The precise number of bacteria, measured in Colony Forming Units (CFU), depends on whether you choose sachets or capsules.

Vivomixx Sachets: The 450 Billion Dose

Standard Vivomixx powder sachets each contain at least 450 billion live lactic acid bacteria and bifidobacteria. This high dose is intended to help replenish and balance the gut microbiota, which naturally hosts trillions of microorganisms. For best results, the powder should be dissolved in a cold, non-carbonated drink and consumed immediately.

Vivomixx Capsules: The 112 Billion Dose

Vivomixx also comes in a capsule format, providing at least 112 billion live bacteria per capsule. While less potent than the sachet, this is still a high count compared to many competitors, offering a convenient option for getting a substantial bacterial dose.

The Neo Formulation: An Even Higher Count

A newer product, Vivomixx Neo, offers slightly different formulations with higher bacterial counts: 460 billion bacteria per sachet and 115 billion bacteria per capsule. The Neo version also includes an additional ninth bacterial strain, Lacticaseibacillus rhamnosus IMC 501, for enhanced action.

The Researched De Simone Formulation

The bacteria in Vivomixx are part of the well-documented "De Simone Formulation." This specific blend comprises eight bacterial strains chosen for their synergistic effects. The formulation was previously sold under the VSL#3 brand name before 2016. The combination of strains works together more effectively than individual strains to support a balanced intestinal flora.

The eight strains in the original formulation include:

Streptococcus thermophilus DSM 24731®
Bifidobacterium breve DSM 24732®
Bifidobacterium longum DSM 24736®
Bifidobacterium infantis DSM 24737®
Lactobacillus acidophilus DSM 24735®
Lactobacillus plantarum DSM 24730®
Lactobacillus paracasei DSM 24733®
Lactobacillus delbrueckii subsp. bulgaricus DSM 24734®

Why Potency Matters: Gut Colonization

For a probiotic to be effective, its beneficial bacteria need to survive passage through the stomach and successfully establish themselves in the gut. A higher CFU count increases the likelihood that enough bacteria will reach the intestines to have a therapeutic effect. Since the gut contains trillions of bacteria, introducing billions more beneficial bacteria can significantly influence the overall microbiota balance, which is particularly important when the gut flora is disrupted, such as after antibiotic use.

Usage and Storage Guidelines

To maintain the high bacterial count, proper handling and storage of Vivomixx are essential. The live bacteria are sensitive to heat, so refrigeration is necessary for long-term storage.

Key guidelines include:

Store Vivomixx in the refrigerator at 2-8°C.
It can be kept at room temperature (up to 25°C) for up to a week without significant loss of potency, but avoid high temperatures.
When using sachets, dissolve the powder in a cold, non-carbonated liquid like water or yogurt and consume immediately.
Do not mix Vivomixx with hot food or drinks, as heat can kill the bacteria.
Taking Vivomixx before breakfast is often recommended for best results.

Vivomixx Product Comparison


Feature	Standard Sachet	Standard Capsule	Neo Sachet	Neo Capsule
Bacterial Count (CFU)	450 Billion	112 Billion	460 Billion	115 Billion
Number of Strains	8	8	9	9
Form	Powder to dissolve	Capsule	Powder to dissolve	Capsule
Strains	De Simone Formula	De Simone Formula	De Simone Formula +1	De Simone Formula +1
Allergen Info	May contain traces of milk	May contain traces of milk	Free from milk proteins	Free from milk proteins

Conclusion

Vivomixx is a high-potency probiotic distinguished by its substantial bacterial count, offering 450 billion CFU in standard sachets and 112 billion CFU in standard capsules, with Neo versions having slightly higher counts. This multi-strain formulation, based on the clinically studied De Simone blend, is designed to maximize gut colonization and support digestive health, setting it apart from many lower-dose probiotics. Understanding the specific bacterial count helps users choose the appropriate format and dosage for their needs.

For additional information about Vivomixx, you can consult the official website to explore details on their various products and their benefits Vivomixx® - Probiotic Facts and Information.

Frequently Asked Questions

A standard Vivomixx sachet contains 450 billion live bacteria, which are also referred to as Colony Forming Units (CFU).

Each Vivomixx capsule provides 112 billion live bacteria from the same eight-strain formulation found in the sachets.

Vivomixx Neo contains a higher bacterial count (460 billion per sachet) and features nine strains, including one additional strain compared to the standard eight-strain formula.

Vivomixx must be refrigerated (at 2-8°C) to maintain the viability and maximum potency of the live, heat-sensitive bacterial strains.

Yes, but you should take Vivomixx as far apart from your antibiotic dose as possible to prevent the antibiotics from killing the beneficial bacteria.

Yes, Vivomixx contains the same proprietary De Simone Formulation that was originally sold under the brand name VSL#3 until 2016.

When first starting Vivomixx, some people may experience temporary bloating as their digestive tract adjusts to the new bacteria. This is a normal physiological process.