Understanding Glycyrrhizin: The Key Factor in Liquorice Safety
The safety of liquorice is primarily linked to glycyrrhizin, a compound in liquorice root responsible for its sweet taste and potential health risks. Glycyrrhizin acts similarly to the hormone aldosterone, which helps regulate the body's salt and water balance. High levels of glycyrrhizin can disrupt this balance, leading to sodium and water retention and potassium loss, a condition called pseudohyperaldosteronism. This imbalance can result in various health problems. Excessive liquorice consumption may lead to electrolyte imbalances with several adverse effects, including high blood pressure (hypertension), low potassium (hypokalemia), heart problems, and other symptoms like swelling and fatigue.
Official Guidelines and Individualized Risk
Defining a precise safe amount of liquorice is challenging due to the variable glycyrrhizin content in products. Historically, the WHO and the European Commission Scientific Committee on Food suggested a daily limit of 100 mg of glycyrrhizin for healthy adults. However, recent research suggests that even this amount might be too high for some individuals. Therefore, consuming genuine liquorice in moderation and infrequently is the most prudent approach. Certain individuals face higher risks and should be particularly cautious or avoid glycyrrhizin-containing liquorice altogether, including those with heart or kidney conditions, high blood pressure, pregnant women, and people taking specific medications.
Differentiating Products and Avoiding Glycyrrhizin
Many candies flavored like licorice, such as red licorice, do not contain actual liquorice root and thus have no glycyrrhizin; they often use anise oil for flavor. Genuine black liquorice, some herbal teas, and certain health supplements do contain real liquorice root and its active compounds. Deglycyrrhizinated licorice (DGL) products are processed to remove most of the glycyrrhizin, offering a safer alternative for those seeking the potential benefits of liquorice without the associated risks.
Comparison Table: Standard vs. Deglycyrrhizinated (DGL) Liquorice
| Feature | Standard Liquorice (Glycyrrhiza glabra) | Deglycyrrhizinated Liquorice (DGL) |
|---|---|---|
| Glycyrrhizin Content | Present in varying, often high, concentrations. | Glycyrrhizin removed to negligible levels. |
| Primary Risks | High blood pressure, low potassium (hypokalemia), water retention, cardiac issues. | Risks are significantly lower; generally considered safe. |
| Common Uses | Candy flavoring, some herbal teas, traditional remedies. | Heartburn relief, stomach ulcers, digestive support. |
| Recommended Intake | Health authorities advise caution; suggested limit is ~100mg glycyrrhizin daily, but lower intake is prudent. | Higher doses can be used safely for longer periods under medical supervision. |
| Who Should Avoid? | High-risk groups including pregnant women and those with heart or kidney conditions. | Most people tolerate DGL well; consultation advised for specific conditions. |
What to Do If You've Had Too Much
If you consume a large amount of genuine liquorice and experience symptoms like swelling, weakness, or heart palpitations, stop immediately and seek medical attention. A doctor can assess the electrolyte imbalance and recommend treatment, likely involving potassium replacement. While recovery usually follows stopping liquorice intake, hormone levels may take weeks or months to normalize.
Conclusion: Moderation is Key for Liquorice Consumption
Liquorice's safety is primarily linked to its glycyrrhizin content, which can affect blood pressure and potassium. Read labels carefully; most 'licorice-flavored' candies lack real liquorice, but black licorice, teas, and supplements often contain it. Consume glycyrrhizin products only occasionally and moderately, or use deglycyrrhizinated licorice (DGL) for benefits without the risks. Consult a healthcare professional about liquorice safety, especially if pregnant, have health conditions, or take medications. For more information on licorice root, see {Link: NCCIH https://www.nccih.nih.gov/health/licorice-root}. Potential signs of excessive liquorice intake include swelling, headaches, tiredness, muscle issues, and heart palpitations. Those with heart, blood pressure, or kidney issues, pregnant women, or those on certain medications should avoid it. Checking labels for 'licorice extract' or 'glycyrrhizin' helps identify true liquorice, and DGL is a safer alternative. Safe practices include using DGL, starting with small amounts of true liquorice, and limiting prolonged use. Always follow medical advice regarding liquorice consumption. Report any concerning symptoms to a doctor.