How much protein is in an italian beef sandwich?

December 29, 2025 •

3 min read

With protein content that can vary dramatically based on the preparation and portion size, the classic Italian beef sandwich offers a range of nutritional profiles. A single sandwich can contain anywhere from 33 to over 78 grams of protein, making it a potentially significant source of this essential macronutrient. This variation depends on several factors, including the cut of beef, the amount of meat used, and whether additional ingredients like cheese are added.

Quick Summary

The protein content of an Italian beef sandwich varies significantly, ranging from approximately 33g to over 78g, based on beef quantity, cut, and toppings. Different recipes and restaurant preparations result in a wide nutritional spread. Customizing the sandwich's ingredients can easily modify its protein, calorie, and fat composition.

Key Points

High Variability: The protein content of an Italian beef sandwich can range from approximately 33g to over 78g, depending on the serving size and toppings.
Key Influencers: The primary factors affecting protein levels are the amount of beef, the specific cut of meat, and whether high-protein extras like cheese are included.
Restaurant Differences: Different restaurants have distinct preparations; a regular Portillo's sandwich has about 33g of protein, while a Lou Malnati's with cheese has closer to 78g.
Customization for Protein Goals: To increase protein, add more beef or cheese. For lower protein, opt for less meat and no cheese.
Comparison to Other Sandwiches: Italian beef sandwiches, especially larger or cheesy versions, often contain significantly more protein than standard fast-food burgers or hot dogs.

Italian Beef Protein: Understanding the Variance

Unlike a standardized product, the protein found in an Italian beef sandwich is not a fixed number. It's a variable influenced by the cook's choices, from the specific cut of beef used to the final portion size. For example, a sandwich from a popular chain like Portillo's may offer around 33g of protein, while a larger, mozzarella-laden version from Lou Malnati's could pack a much higher 78g. Understanding these variables is key to assessing how an Italian beef sandwich fits into your dietary goals.

Factors Influencing Protein Content

Several elements contribute to the final protein count of your Italian beef sandwich:

Amount of Beef: This is the most significant factor. A sandwich piled high with extra beef will naturally contain more protein than a standard serving. The weight of the cooked meat is the primary driver of protein content.
Cut of Beef: The type of beef roast, such as chuck or top round, can affect the protein-to-fat ratio. Leaner cuts provide a higher concentration of protein per gram of meat.
Added Cheese: Adding cheese like provolone or mozzarella significantly increases the overall protein. For instance, Lou Malnati's version with mozzarella has a higher protein count than leaner preparations.
Bread and Preparation: While the bread itself contributes some protein, the main source is the beef. The method of cooking the beef and the amount of au jus (beef broth) it's served with will affect its final weight and, by extension, its protein.

Example Protein Values from Popular Sources

To illustrate the wide range, here are some examples of the protein content found in Italian beef sandwiches from different sources:

Portillo's Italian Beef Sandwich: Approximately 33g of protein for a regular sandwich.
Lou Malnati's Italian Beef with Mozzarella: A robust 78g of protein.
Colorado Beef Council Recipe: A homemade recipe yields around 36g of protein per serving.
Generic Sandwich (Nutritionix): One generic Italian beef sandwich was reported to have 52g of protein.
Vienna Beef Italian Beef (Deli Meat): For just the beef, a 3 oz serving provides 18g of protein.

How to Adjust the Protein in Your Italian Beef Sandwich

For those looking to customize their intake, here are some ways to modify the protein in your sandwich:

To Increase Protein:

Add Extra Beef: Simply order or prepare your sandwich with a double portion of meat. This is the most direct method to boost the protein content.
Top with Provolone or Mozzarella: These cheeses are excellent sources of protein and will significantly raise the total count. For example, adding provolone can increase protein by several grams.
Include High-Protein Vegetables: While small, adding protein-rich vegetables like mushrooms (as some recipes suggest) can add a minor boost.

To Decrease Protein (and Calories):

Portion Control: Order a smaller sandwich or use less beef in your homemade version.
Skip the Cheese: Opting for a plain Italian beef will reduce both protein and fat.
Consider an Open-Face Sandwich: Using a single piece of bread can help reduce overall carbs and calories, though the protein from the meat remains.

Italian Beef vs. Other Sandwiches: A Protein Comparison


Sandwich Type	Typical Protein Range (grams)	Notes
Italian Beef Sandwich	33–78g+	Highly variable depending on meat portion, toppings like cheese, and restaurant.
Subway 6" Chicken Bacon Ranch Melt	25–42g	Standard 6-inch sub; double meat option significantly increases protein.
Subway 6" Supreme Meats	25–51g	Contains multiple Italian meats and cheese, so fat and protein are higher.
Wendy's Grilled Chicken Sandwich	34g	A leaner fast-food grilled chicken option.
Hamburger	~20g	Typically lower protein per serving than a large Italian beef, but varies by patty size.
Hot Dog	~5–10g	Much lower protein due to smaller size and processing.

Conclusion

The amount of protein in an Italian beef sandwich is not a simple figure but rather a range that depends heavily on how it is prepared and served. With protein values spanning from the mid-30s to nearly 80 grams, it can be a hearty, high-protein meal or a more moderate option. Homemade versions and specific restaurant preparations show the most significant variation, often influenced by the quantity of beef and the addition of cheese. By being mindful of these factors, you can enjoy this classic sandwich while controlling its nutritional impact.

For more detailed nutritional information on individual ingredients like different cuts of beef, you can consult resources such as the USDA FoodData Central database. [Citation needed]

Frequently Asked Questions

To make a higher-protein Italian beef sandwich at home, start with a larger, leaner cut of beef roast. Increase the amount of meat per serving and add provolone or mozzarella cheese. Using a high-quality broth can also enhance flavor without compromising the protein content.

Yes, adding cheese like provolone or mozzarella can significantly increase the protein. For example, a Lou Malnati's sandwich with mozzarella has a much higher protein count (78g) than a plainer version (33g).

A substantial Italian beef sandwich typically has more protein than a standard hamburger. While a hamburger has about 20g of protein, large or cheesy Italian beef sandwiches can offer over 50g, though this varies greatly by serving size and toppings.

To estimate the protein in a homemade sandwich, measure the cooked, shredded beef. A 3-ounce serving of lean Italian beef can provide around 18g of protein. Calculate based on how much meat you use, and add protein for any cheese or other toppings.

No, they are not equal. As shown by different brands like Portillo's and Lou Malnati's, protein counts vary significantly due to differences in portion sizes, types of beef, and the inclusion of toppings like cheese.

Chuck roast and top round are common cuts used for Italian beef. Leaner cuts like top round will have a slightly higher protein-to-fat ratio, but the overall protein is more dependent on the total quantity of meat used.

Yes, a larger, meat-heavy Italian beef sandwich can be an excellent source of protein for muscle building, especially if you are mindful of overall calories and fat intake. Opting for a leaner cut of beef can further support this goal.