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Incomplete Proteins: What Type of Protein Is Lacking One or Two of the Essential Amino Acids?

4 min read

According to the National Institutes of Health, there are nine essential amino acids that the human body cannot produce on its own. The type of protein that is lacking one or more of these essential amino acids is known as an incomplete protein.

Quick Summary

Incomplete proteins are missing one or more of the nine essential amino acids necessary for the body's functions, and are predominantly found in plant-based food sources. A balanced diet featuring a variety of plant proteins can supply all essential amino acids throughout the day.

Key Points

  • Incomplete Proteins Defined: These food sources lack one or more of the nine essential amino acids required by the human body.

  • Sources Are Primarily Plant-Based: Most incomplete proteins are found in plants like grains (low in lysine), legumes (low in methionine), and nuts and seeds (can be low in either).

  • Complementary Proteins:** By eating a variety of incomplete protein sources, such as rice and beans, over the course of a day, you can achieve a complete amino acid profile.

  • Certain Plants Are Complete: Some plant-based foods like quinoa, soy (tofu, tempeh), and buckwheat are naturally complete proteins and provide all essential amino acids.

  • Protein Combining Is Flexible: You do not need to combine specific complementary proteins at every meal; eating diverse protein sources throughout the day is sufficient.

  • Serious Deficiency Is Rare: For those with access to varied food, a deficiency is unlikely, but a prolonged imbalanced diet can lead to health issues such as edema, weakened immunity, and muscle loss.

In This Article

What Defines an Incomplete Protein?

Protein is a crucial macronutrient made up of building blocks called amino acids. Of the 20 amino acids used by the human body, nine are deemed "essential" because our bodies cannot synthesize them; they must be obtained from dietary sources. An incomplete protein is a food source that contains some, but not all, of these nine essential amino acids. These are different from "complete proteins," which provide all nine essential amino acids in sufficient quantities. The limiting amino acid in an incomplete protein is the essential amino acid that is in the shortest supply relative to the body's needs, and it dictates the overall rate of protein synthesis from that source.

Common Sources of Incomplete Proteins

Most incomplete proteins are plant-based, though not exclusively. Many staples of plant-based diets are incomplete, but can be combined to form a complete amino acid profile.

  • Legumes: Beans, lentils, and peas are classic examples. Their limiting amino acid is often methionine.
  • Grains: Rice, wheat, and corn are typically low in lysine.
  • Nuts and Seeds: These can be low in lysine or methionine.
  • Vegetables: Many vegetables are also considered incomplete sources, often lacking methionine.
  • Collagen: A unique example, collagen is an animal-based protein that is incomplete because it lacks the essential amino acid tryptophan.

The Concept of Complementary Proteins

For a long time, it was believed that vegetarians and vegans needed to carefully combine specific incomplete proteins at every meal to create a complete protein. This is known as protein complementation. Examples include pairing rice and beans or a peanut butter sandwich on whole-wheat bread. Modern nutritional science, however, has shown that our bodies can maintain a pool of amino acids from various meals throughout the day. This means it is sufficient to consume a variety of protein sources over the course of a day to ensure all essential amino acids are acquired.

How to Create a Complete Amino Acid Profile

To build a complete amino acid profile from plant-based foods, you need to combine different categories of foods that compensate for each other's missing essential amino acids.

  • Grains and Legumes: A timeless pairing. Grains like rice lack lysine, which is abundant in legumes such as beans.
  • Nuts/Seeds and Legumes: Combining seeds like pumpkin seeds with lentils creates a more complete profile. For instance, lysine in legumes complements the methionine often found in sufficient quantities in nuts and seeds.
  • Dairy and Grains/Legumes: For lacto-ovo vegetarians, dairy products like cheese or yogurt can provide the missing essential amino acids to complement plant-based meals.

Complete Proteins from Plant Sources

While most plant-based proteins are incomplete, some foods are naturally complete proteins and do not require combination. These are excellent choices for adding to a plant-based diet.

  • Quinoa: A gluten-free grain that is a complete protein.
  • Soy Products: Tofu, tempeh, and edamame contain all nine essential amino acids.
  • Buckwheat: Another complete plant-based protein source.
  • Hempseed: A nutritious complete protein often used in vegan diets.

Comparison: Complete vs. Incomplete Proteins

This table outlines the key differences between complete and incomplete proteins.

Feature Complete Proteins Incomplete Proteins
Definition Contains all nine essential amino acids in sufficient quantities. Lacks or is low in one or more of the nine essential amino acids.
Typical Sources Animal products (meat, fish, eggs, dairy) and a few select plant foods (soy, quinoa). Most plant-based foods, including grains, legumes, nuts, and vegetables.
Dietary Strategy Provides a complete amino acid profile in a single food item. Requires combining different sources over the course of a day to achieve a complete profile.
Amino Acid Profile Balanced and robust for immediate use in protein synthesis. One or more "limiting amino acids" restrict its full utilization if eaten alone.

The Health Implications of Incomplete Protein Intake

Consuming incomplete proteins as part of a varied diet is perfectly healthy and safe. The historical concern that vegans or vegetarians might be at risk of protein deficiency has largely been dispelled, as our bodies are efficient at assembling amino acids from diverse sources over time. However, a diet that consistently lacks a varied intake of essential amino acids can have health consequences. A consistent deficiency can hinder protein synthesis, compromising tissue repair and maintenance. In severe cases, this can lead to symptoms like edema (swelling), weakened immunity, muscle wasting, stunted growth in children, and even anemia. This is not a common issue for individuals with access to a variety of foods, but it highlights the importance of dietary diversity. A balanced and varied intake of plant foods throughout the day, rather than strict meal-by-meal pairing, is the recommended approach for meeting protein requirements.

Conclusion

An incomplete protein is a food source that lacks one or more of the nine essential amino acids. These are primarily plant-based foods, but a few animal proteins like collagen also fall into this category. The key to obtaining a complete protein profile on a plant-based diet is to consume a variety of incomplete protein sources throughout the day, allowing the body to assemble all the necessary amino acids. The myth that specific combinations must be eaten together at each meal has been debunked by modern nutritional understanding, which recognizes the body's ability to maintain an amino acid pool. Embracing a diverse array of grains, legumes, nuts, and seeds is a simple and effective strategy for ensuring adequate intake of all essential amino acids for optimal health and bodily function.

Visit the official website of the American Society for Nutrition for more information on protein complementation and dietary guidelines.

Frequently Asked Questions

The primary difference is the amino acid content. A complete protein contains all nine essential amino acids in adequate amounts, while an incomplete protein lacks one or more of them.

Generally, no. As long as they consume a varied diet that includes a wide range of plant-based protein sources, they can easily obtain all essential amino acids over the course of a day. The body maintains an amino acid pool it can draw from.

A limiting amino acid is the essential amino acid that is in the shortest supply within a food source. It dictates how efficiently the body can use that protein source for synthesis.

A classic example is rice and beans. The limiting amino acid in rice (lysine) is abundant in beans, and the limiting amino acid in beans (methionine) is found in rice, creating a complete amino acid profile when eaten together.

No. While most plant proteins are incomplete, there are notable exceptions. Quinoa, soy products (tofu, tempeh), and buckwheat are examples of complete plant-based proteins.

No, this is a myth. Scientific consensus states that it is not necessary to combine complementary proteins in a single meal. The body can use the pool of amino acids it gathers throughout the day from various food sources.

Yes, although it is rare. For example, collagen, which is derived from animal sources, is considered an incomplete protein because it lacks the essential amino acid tryptophan.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.