Evion, a popular Vitamin E supplement, is a common name in health and beauty routines, but many users question the origin of its active ingredient. The answer is critical for consumers who prioritize either natural or synthetic sources for their supplements. To determine if Evion is natural or synthetic, one must first understand the fundamental molecular differences between the two types of Vitamin E.
What is Evion's active ingredient?
Evion capsules contain Tocopheryl Acetate. The full chemical name is all-rac-α-tocopheryl acetate or dl-alpha tocopheryl acetate. The dl- prefix indicates a synthetic origin, manufactured in a lab, rather than directly from a natural plant source. Some descriptions may use the general term "natural antioxidant", but this doesn't denote its source.
Natural vs. Synthetic Vitamin E: A Molecular Difference
The key difference between natural and synthetic Vitamin E lies in their molecular structure and how the body utilizes them. Alpha-tocopherol is the primary form associated with biological activity.
Molecular structure
- Natural Vitamin E: Known as d-alpha-tocopherol or RRR-alpha-tocopherol, this single isomer is found in plant oils and seeds. The body's transport proteins recognize this structure efficiently.
- Synthetic Vitamin E: Labelled as dl-alpha-tocopherol or all-rac-alpha-tocopherol, it is a mix of eight stereoisomers, only one matching the natural form.
Bioavailability and body retention
The body's ability to absorb and use Vitamin E is impacted by its structure. The liver selectively transports the natural d-alpha form, leading to better retention. Natural Vitamin E is approximately twice as bioavailable as synthetic Vitamin E, meaning a higher dose of the synthetic form is needed for equivalent effect.
The use of esters like Tocopheryl Acetate
Using tocopheryl acetate instead of pure tocopherol improves stability and extends shelf life by preventing degradation from oxygen. The body breaks down the acetate ester in the gut to absorb the free tocopherol.
Comparison of Natural and Synthetic Vitamin E
| Feature | Natural Vitamin E (d-alpha) | Synthetic Vitamin E (dl-alpha) |
|---|---|---|
| Source | Plant oils (e.g., sunflower, soybean) | Petrochemicals, manufactured in a lab |
| Molecular Structure | Single isomer (RRR-alpha-tocopherol) | Racemic mixture of eight isomers |
| Bioavailability | Higher, roughly twice as potent | Lower, less efficiently utilized by the body |
| Cost | Typically more expensive due to extraction process | Less expensive due to industrial manufacturing |
| Stability | Less stable in its pure form, but acetate ester is stable | Stable, especially in its acetate ester form |
Why choose one over the other?
Both natural and synthetic Vitamin E offer antioxidant benefits. The choice often depends on cost and preference for natural sources. The higher bioavailability of the natural form may be preferred for perceived potency. The synthetic option is a stable and more affordable alternative. Dietary sources of natural Vitamin E include wheat germ oil, sunflower seeds, almonds, and spinach. For more details, consult resources like the Office of Dietary Supplements at the National Institutes of Health.
Conclusion
Evion contains dl-alpha-tocopheryl acetate, a synthetic, lab-manufactured Vitamin E. It differs from natural d-alpha-tocopherol found in foods, primarily in its molecular structure and lower bioavailability. This information helps consumers make informed choices based on their priorities and preferences for supplement sources.
