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Is it okay to drink comfrey tea? A comprehensive safety guide

4 min read

According to the U.S. Food and Drug Administration (FDA), all oral comfrey products were advised to be removed from the market in 2001 due to serious health concerns, including severe liver damage. This warning applies directly to the practice of drinking comfrey tea, which contains toxic compounds known as pyrrolizidine alkaloids (PAs).

Quick Summary

Despite its long history in traditional medicine, oral consumption of comfrey tea is considered dangerous by health authorities due to toxic pyrrolizidine alkaloids (PAs). PAs can cause severe and irreversible liver damage, potentially leading to liver failure and cancer. The risks are dose-dependent, but all internal use is strongly discouraged. Comfrey is now recommended for external use only on unbroken skin, under strict precautions.

Key Points

  • Internal Use is Unsafe: Drinking comfrey tea is strongly discouraged due to the presence of toxic pyrrolizidine alkaloids (PAs).

  • Causes Liver Damage: Ingested PAs can cause severe liver damage, known as sinusoidal obstruction syndrome (SOS), and have been linked to liver failure and cancer.

  • FDA Warning Issued: In 2001, the FDA advised manufacturers to remove oral comfrey products from the market due to these dangers.

  • Risks are Insidious: The liver damage can develop slowly over weeks or months, making it difficult to detect and link to comfrey use.

  • Topical Use Has Precautions: While topical use on unbroken skin is generally considered safer, it should be limited and never applied to broken or damaged skin.

  • Safe Alternatives Exist: Safer herbal tea options like ginger, peppermint, and chamomile can be used for wellness and other benefits without the risk of comfrey.

In This Article

Why Drinking Comfrey Tea is Not Safe

While comfrey (Symphytum officinale) has a long history of use as an herbal remedy, modern scientific and regulatory bodies have issued strong warnings against its oral consumption, including as a tea. The primary reason for this is the presence of pyrrolizidine alkaloids (PAs), which are toxic compounds found in the plant's leaves and, in higher concentrations, its roots. When ingested, PAs are metabolized in the liver into highly toxic pyrrole metabolites. This can lead to serious and irreversible health problems.

The Dangers of Pyrrolizidine Alkaloids (PAs)

These alkaloids are responsible for several severe health risks associated with oral comfrey consumption:

  • Sinusoidal Obstruction Syndrome (SOS): Formerly known as hepatic veno-occlusive disease (VOD), this condition is the most recognized severe side effect of comfrey ingestion. It involves the obstruction of the liver's small veins, which can cause significant damage, fluid retention (ascites), and, in severe cases, liver failure.
  • Liver Damage and Carcinogenicity: The toxic metabolites from PAs can directly damage liver cells and DNA, leading to chronic liver damage and fibrosis. Animal studies have linked comfrey ingestion to liver cancer, leading regulators to classify it as a potential carcinogen.
  • Pulmonary Hypertension: In rare cases, comfrey poisoning has been linked to severe pulmonary hypertension, a condition affecting the arteries in the lungs.

Regulatory Actions and Warnings

The consensus among leading health agencies is to avoid internal comfrey use completely. This has led to regulatory actions globally.

  • In 2001, the U.S. FDA advised all dietary supplement manufacturers to remove comfrey products intended for oral consumption from the market.
  • Both Canada and Germany have also restricted the commercial sale and distribution of comfrey due to its proven toxicity.
  • The risks are particularly high for vulnerable populations, including pregnant or breastfeeding women, infants, and individuals with pre-existing liver or kidney conditions.

The Deceptive Nature of Comfrey Toxicity

The danger of comfrey is often insidious. Liver damage can occur over weeks or months and may not be immediately obvious. Symptoms such as jaundice, pain in the upper abdomen, nausea, and fluid retention can be slow to develop. This delayed onset makes linking the herb to the illness difficult, and many historical cases of comfrey poisoning may have gone undiagnosed. The PA content can vary significantly based on the plant part used (roots are more toxic than leaves), its age, and harvesting time, making the dosage unpredictable and dangerous.

External Use vs. Internal Ingestion

While drinking comfrey tea is unsafe, topical application of comfrey preparations is treated differently by health professionals.

  • Topical Application: Comfrey ointments, creams, and poultices have been used for decades to treat skin abrasions, sprains, bruises, and inflammatory conditions like osteoarthritis. These products may offer mild analgesic and anti-inflammatory effects.
  • Absorption Risk: The risk of PA absorption through the skin is considered lower but not non-existent. Therefore, comfrey should only be applied to unbroken skin for limited durations, typically less than 10 days. It is strictly cautioned against use on open wounds, damaged skin, or over long periods.

Comparison of Comfrey Risks: Internal vs. External

Feature Internal Use (e.g., Comfrey Tea) External Use (e.g., Cream/Poultice)
Toxicity Risk Extremely High. Direct and efficient absorption of PAs into the bloodstream and liver. Low, but present. Limited absorption of PAs through unbroken skin.
Main Danger Severe liver damage, sinusoidal obstruction syndrome (SOS), potential carcinogenicity. Potential for systemic toxicity if absorbed through broken skin, or skin irritation.
Health Agency Stance Strongly advised against, restricted, or banned in many countries. FDA recommends removal from market. Generally permitted, but with strict precautions. Use only on unbroken skin for short periods.
Associated Symptoms Jaundice, abdominal pain, nausea, weight gain from fluid retention. Skin irritation, itching, rashes, burning sensations.
Primary Goal No safe therapeutic use supported for oral intake. Anti-inflammatory and wound-healing properties, but evidence for efficacy is limited and use must be cautious.

Safe Alternatives to Comfrey Tea

For those seeking alternatives for internal wellness or inflammatory issues, many safe herbal teas can be substituted:

  • Ginger Tea: Known for its anti-inflammatory and digestive benefits.
  • Peppermint Tea: Excellent for bloating and digestive discomfort.
  • Chamomile Tea: A popular choice for its calming properties.
  • Turmeric Tea: Contains powerful anti-inflammatory compounds.
  • Nettle Leaf Tea: A nutritious tea used traditionally for a variety of ailments.

Note: Always consult a healthcare professional before starting any new herbal regimen, especially if you have pre-existing health conditions, are pregnant, or are taking other medications.

Conclusion

In summary, the internal consumption of comfrey tea is not recommended and is considered unsafe by major health agencies, including the FDA. The presence of toxic pyrrolizidine alkaloids (PAs) poses a significant risk of severe and potentially fatal liver damage. While comfrey has a long history of traditional use, the understanding of its chemical toxicity has evolved, leading to modern-day warnings against ingestion. For topical application on unbroken skin, it carries a much lower risk but still requires caution. Given the availability of numerous safe and effective herbal alternatives, drinking comfrey tea for any perceived internal health benefit is an unnecessary and dangerous risk.

Frequently Asked Questions

Comfrey tea is dangerous to drink because it contains toxic compounds called pyrrolizidine alkaloids (PAs). When ingested, these alkaloids are metabolized into substances that can cause severe and irreversible liver damage, liver failure, and potentially liver cancer.

While not an outright ban, in 2001 the U.S. FDA issued an advisory recommending that all dietary supplement manufacturers remove products containing oral comfrey from the market due to its toxicity. Numerous countries, including Canada and Germany, have restricted its sale and use.

Comfrey is possibly safe for external use on unbroken skin for short periods (typically less than 10 days). However, it should never be applied to broken, damaged, or open skin, as the toxic PAs can be absorbed into the bloodstream.

Symptoms of oral comfrey poisoning can include jaundice, pain in the upper right abdomen, nausea, and weight gain due to fluid retention (ascites). These symptoms may develop insidiously over time.

The only modern application of comfrey considered possibly safe is topical use on unbroken skin, typically for bruises or sprains, and only for short-term periods. However, due to safety concerns and better alternatives, many herbalists still recommend caution.

For a safe and beneficial herbal tea, consider alternatives such as ginger, peppermint, chamomile, or turmeric. These herbs offer various health benefits without the serious risks associated with comfrey.

Pyrrolizidine alkaloids (PAs) are a class of toxic compounds found in various plants, including comfrey. When metabolized in the liver, PAs become highly reactive and toxic, damaging liver cells and small veins, leading to severe health complications.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.