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Is NOVOS a Good Supplement? An In-Depth Longevity Review

4 min read

According to NOVOS's own internal studies, which are not peer-reviewed, the combination of ingredients in NOVOS Core and Boost showed promising results for preventing DNA damage in human cells. But beyond company-led research, is NOVOS a good supplement for those serious about longevity? This review dives deep into the scientific claims and real-world considerations of the NOVOS product line.

Quick Summary

A detailed analysis of the NOVOS longevity supplement system, including Core, Vital, and Boost, examines ingredient quality, clinical evidence, cost-effectiveness, and customer experience.

Key Points

  • Robust Formulation: NOVOS Core contains a dozen science-backed ingredients targeting multiple aging pathways simultaneously.

  • Positive Evidence: Studies show the formulation can protect against cellular damage and extend lifespan in animal models, while many users report improved energy, sleep, and skin.

  • Questionable NMN Value: The NOVOS Boost supplement provides a relatively low dose of NMN for its price compared to competitors.

  • Not for the Budget-Conscious: The comprehensive product line and epigenetic tests are an expensive commitment, especially with a strict and unforgiving return policy.

  • Consult a Professional: Despite a good overall safety profile, consulting a physician is vital due to potential side effects or interactions with specific ingredients like nattokinase or microdosed lithium.

In This Article

Understanding the NOVOS Approach to Longevity

NOVOS is a company in the longevity space that distinguishes itself by combining multi-ingredient supplement formulations with optional epigenetic age testing. The core philosophy is to address the 12 recognized hallmarks of aging simultaneously rather than focusing on a single pathway. This contrasts with many competitors that may offer single-ingredient supplements or less comprehensive blends. The flagship product, NOVOS Core, is a powder mix containing a dozen ingredients, while other products like Vital and Boost offer targeted support.

NOVOS Core: The Foundational Mix

NOVOS Core is positioned as the central component of the system. It comes as a drink mix and contains a blend of 12 ingredients aimed at supporting multiple aspects of aging, including cellular health, DNA protection, and metabolism. Key ingredients include:

  • Alpha-Ketoglutarate (AKG): Studies have shown AKG can extend lifespan in animal models and may support healthy metabolism and muscle function in humans.
  • Fisetin: This flavonoid has shown potential as a senolytic in animal studies, helping to clear senescent cells, though human trials are ongoing.
  • Glycine: An amino acid that naturally declines with age, supplemental glycine has been linked to improved metabolic health and is a building block for collagen.
  • Rhodiola Rosea: An adaptogen used to combat stress, with some animal studies suggesting it can prolong lifespan.
  • Magnesium Malate: Essential for over 300 bodily processes, including sleep regulation, which is vital for long-term health.
  • Hyaluronic Acid: While known for skin health benefits, studies suggest oral hyaluronic acid may improve hydration and reduce wrinkles.
  • Pterostilbene: A powerful antioxidant, NOVOS uses this instead of resveratrol, noting better bioavailability.

Internal studies by NOVOS suggest that the combined formulation can be effective. For example, a mouse study demonstrated an 18% lifespan extension in aged mice, while human cell studies showed significant protection against DNA damage. Customer testimonials often report subjective benefits like increased energy, improved sleep, and better skin complexion within a few weeks to months.

Supporting Formulas: Vital and Boost

To complement the comprehensive Core, NOVOS offers two other supplements: Vital and Boost.

  • NOVOS Vital: These gummies are designed to support specific organs, with ingredients like trehalose, inulin (for gut health), and lutein (for eye health). It provides a more targeted approach than the broad-spectrum Core.
  • NOVOS Boost: This supplement contains Nicotinamide Mononucleotide (NMN), an NAD+ precursor important for mitochondrial function. However, at 250mg per dose, the NMN is at the lower end of clinically studied dosages, with some competitors offering higher amounts for a better price.

The Verdict: Weighing the Pros and Cons

Pros of NOVOS:

  • Comprehensive Formulation: The Core formula is robust and targets multiple aging pathways based on scientific principles.
  • Evidence-Backed Ingredients: Many ingredients in Core and Vital are supported by independent scientific research, though some dosages and combinations require more human study.
  • Tackles Multiple Hallmarks: Unlike single-molecule competitors, NOVOS addresses several facets of aging simultaneously.
  • Effective Combination: A mouse study showed impressive lifespan extension for the Core formula, and customer reports often note perceptible benefits.
  • Taste and Convenience: Core is offered as a convenient drink mix or powder, while Vital is a gummy, offering a pleasant alternative to swallowing many pills.

Cons of NOVOS:

  • High Cost: While competitive in the multi-ingredient category, the overall cost, especially with the optional epigenetic test, can be substantial.
  • Underdosed NMN: The NMN in NOVOS Boost is on the lower end of effective doses seen in research and is relatively expensive compared to other NMN suppliers.
  • Proprietary Research: Some of the most impressive results come from company-sponsored or non-peer-reviewed studies, which may have inherent bias.
  • Poor Return Policy: A strict return policy with high restocking and shipping fees means that dissatisfied customers cannot get their money back after trying the product.

Comparison of NOVOS Product Offerings

Feature NOVOS Core NOVOS Vital NOVOS Boost
Primary Goal Comprehensive anti-aging & cellular health Organ function support NAD+ boosting & energy support
Format Powder mix (orange or unflavored) Gummies Capsules
Active Ingredients 12 longevity ingredients 7 organ-specific ingredients 125mg NMN per capsule
Cost-Effectiveness Strong value for a comprehensive blend, competitive pricing Convenient and reasonably priced support for vital organs Weaker value proposition; lower dose and higher cost than some NMN competitors
Experience Tangy taste, minor GI issues possible initially Chewy, pleasant taste, low risk of discomfort Standard capsules, some users increase dosage for more energy

The Importance of Safety and Physician Consultation

While NOVOS's products generally have a good safety profile, some ingredients warrant consideration. Nattokinase, found in Vital, is derived from fermented soy and can cause an allergic reaction in those with soy sensitivity. A small percentage of users also experience minor stomach discomfort when starting Core or Vital as their digestive system adjusts. The microdose of lithium in Core is well below therapeutic levels but can still be a concern for some. It is crucial to speak with a healthcare provider before adding any new supplement, including NOVOS, to your regimen, especially if you have pre-existing health conditions or take other medications.

Conclusion

So, is NOVOS a good supplement? For individuals committed to a comprehensive longevity regimen and willing to invest in a multi-ingredient approach, NOVOS Core is a well-formulated, science-backed option with promising evidence and positive user feedback. However, for those primarily seeking NMN, NOVOS Boost offers less value compared to alternative products on the market. The high cost and unfriendly return policy are also notable drawbacks. Ultimately, NOVOS presents a strong contender in the longevity space for those who appreciate its integrated approach, but careful consideration of individual goals, budget, and potential side effects is essential before purchasing. To learn more about the specific ingredients and studies referenced in NOVOS's formulations, visit their website.

Frequently Asked Questions

Many users report experiencing noticeable benefits such as improved energy, mood, and skin health within 30 days of consistent use. Long-term benefits related to longevity and cellular health may not be immediately perceptible.

A small percentage of users report initial stomach discomfort. It is recommended to take the supplement with or after a meal, split the dose into smaller servings throughout the day, or mix it with more water.

The ingredients in NOVOS are generally recognized as safe (GRAS) by the FDA and have a low side effect profile. However, some ingredients lack extensive human data at the specific microdoses used, so consultation with a doctor is always recommended.

NOVOS claims its synergistic formulation provides more benefits than simply combining individual ingredients. The company also argues that purchasing their blend is more cost-effective than buying all 12 specialty ingredients separately.

The NOVOS Age test is an optional epigenetic test that uses the DunedinPACE algorithm to measure your rate of aging over time. It is considered highly relevant and accurate by many scientists in the field for measuring the impact of lifestyle interventions.

Yes, NOVOS Boost contains NMN. However, at 250mg per dose, it is on the lower end of studied dosages and is generally considered more expensive than other NMN supplements on the market.

NOVOS has a very strict and unfavorable return policy. Only unopened products can be returned within 30 days, and returns are subject to significant shipping and restocking fees, often making the return not financially worthwhile.

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.