Is There Caffeine in EGCG? Unpacking the Difference

December 9, 2025 •

3 min read

According to scientific research, epigallocatechin gallate (EGCG) is a plant compound, while caffeine is a separate stimulant, though both are famously found in green tea. This fundamental distinction is key to understanding whether there is caffeine in EGCG and how to manage your intake of each.

Quick Summary

EGCG and caffeine are distinct compounds often found together in green tea and its extracts. While EGCG is a polyphenol and antioxidant, caffeine is a stimulant. The presence of caffeine depends on the source, whether it's brewed tea or a supplement, and how it is processed.

Key Points

Distinct Compounds: EGCG is a polyphenol antioxidant, while caffeine is a stimulant; they are chemically different molecules.
Varying Content: The amount of caffeine accompanying EGCG depends on the source, such as brewed green tea, matcha, or supplements.
Decaffeinated Sources: You can find EGCG without the stimulant by choosing decaffeinated green tea or targeted supplements.
Synergistic Effects: EGCG and caffeine can work together, and their combination is often studied for its effect on metabolism and weight loss.
Label Reading is Key: Always check product labels, especially for concentrated green tea extracts, to know the precise caffeine and EGCG content.

Understanding EGCG and Caffeine: The Chemical Distinction

EGCG (Epigallocatechin gallate) is a specific type of plant-based antioxidant, known as a catechin, which is a subgroup of polyphenols. Its molecular formula is C22H18O11. Caffeine, conversely, is a naturally occurring stimulant alkaloid with the molecular formula C8H10N4O2. They are two entirely different molecules with separate chemical structures and effects on the body. The confusion often arises because they are both naturally present in the leaves of the Camellia sinensis plant, the source of green tea.

EGCG vs. Caffeine: Key Differences

Molecular Structure: EGCG is a complex polyphenol, while caffeine has a distinct and much simpler alkaloid structure.
Primary Function: EGCG is primarily known for its powerful antioxidant properties. Caffeine is a central nervous system stimulant that affects alertness.
Source: Both are found in tea leaves but are not bound and can be separated. EGCG is also in some fruits and nuts without caffeine.
Effects on the Body: EGCG supports health through antioxidant action. Caffeine provides an energy boost and can increase heart rate.

Sources of EGCG and Their Caffeine Content

EGCG sources have varying caffeine levels.

EGCG from Brewed Green Tea

An 8-ounce cup of green tea has 30 to 50 mg of caffeine and significant EGCG. Amounts depend on factors like leaf type, water temperature, and steeping time. Matcha has higher EGCG and caffeine as the whole leaf is consumed.

EGCG from Green Tea Extract Supplements

These offer concentrated EGCG, but caffeine content varies. Some extracts are decaffeinated, while others are high in caffeine. Check the label for specific content.

EGCG from Decaffeinated Green Tea

Decaf green tea has most caffeine removed but retains beneficial EGCG and polyphenols. It's good for those sensitive to caffeine. Natural decaffeination preserves more compounds.

EGCG from Other Foods

Besides green tea, smaller EGCG amounts are in:

Blackberries
Strawberries
Pecans
Hazelnuts
Avocados
Kiwi

How to Separate EGCG and Caffeine

Techniques like macroporous resin adsorption, chromatography, and liquid-phase extraction separate EGCG from caffeine for pure EGCG production.

Comparison of EGCG and Caffeine in Different Products


Product	EGCG Content	Caffeine Content	Key Takeaway
Brewed Green Tea (8 oz)	Moderate (50–100 mg)	Moderate (30–50 mg)	Both compounds are present; quantities vary by brewing and type.
Matcha Green Tea	Higher concentration than brewed tea	Higher concentration than brewed tea	Made from the whole leaf, so you consume more of both compounds.
Green Tea Extract (Capsule)	Varies widely (e.g., 325 mg+)	Varies widely (e.g., 0 to 200 mg+)	Check the label for specific amounts of EGCG and caffeine.
Decaffeinated Green Tea	Reduced, but still present	Minimal (2–5 mg)	Suitable for those sensitive to caffeine.

Synergistic and Independent Effects of EGCG and Caffeine

EGCG and caffeine can act together. Research on weight loss explores their synergistic effect on thermogenesis, though studies have varying conclusions on the significance and which compound is more responsible. Other studies show a stronger synergistic effect with low doses.

For those with health conditions or caffeine sensitivity, understanding individual effects is vital. Decaffeinated EGCG offers antioxidants without caffeine's stimulant effect. For a metabolic boost, a product with both is better. Consult a healthcare professional to determine appropriate dosage and products.

Conclusion: Navigating EGCG and Caffeine Intake

EGCG is a distinct antioxidant catechin separate from caffeine. Their presence together in tea and supplements can be confusing, but product choices allow control over intake. Green tea or matcha provides both. Decaf tea and specific supplements offer EGCG without caffeine. Awareness of product formulation is key for personal health goals.

The Difference Between EGCG and Caffeine

EGCG and caffeine are distinct molecules: EGCG is an antioxidant polyphenol, whereas caffeine is a stimulant.
Green tea contains both: The tea plant Camellia sinensis naturally produces both compounds.
Caffeine levels vary: The amount of caffeine in a product depends on the source and processing method.
Decaffeinated options exist: It is possible to consume EGCG with minimal caffeine through decaf tea or specific supplements.
Synergy in supplements: In some cases, EGCG and caffeine are combined in supplements to enhance certain effects.
Check the label: Always read labels carefully to understand the exact EGCG and caffeine content.
Consult a professional: If you are sensitive to caffeine or have health concerns, consult a healthcare provider for guidance.

Frequently Asked Questions

No, EGCG and caffeine are two entirely different chemical compounds. EGCG is an antioxidant polyphenol found in tea, while caffeine is a stimulating alkaloid also found in tea, but they are not the same molecule.

Yes, decaffeinated green tea still contains EGCG and other beneficial polyphenols. While some compounds might be lost during the decaffeination process, a significant amount of EGCG remains.

A standard 8-ounce cup of green tea typically contains between 30 and 50 mg of caffeine. This can vary based on the brewing method, leaf type, and steeping time.

The caffeine content in green tea extract supplements varies widely. Some products are specifically decaffeinated, while others may contain significant amounts. It is essential to check the product's label for details.

While green tea is the most potent source, EGCG is also found in smaller concentrations in other foods, such as blackberries, strawberries, pecans, hazelnuts, and avocados.

Yes, EGCG and caffeine can be separated through industrial and laboratory processes, such as chromatography and selective extraction, allowing for the production of pure EGCG or decaffeinated extracts.

Both EGCG and caffeine are thought to contribute to green tea's metabolic effects. Some research suggests a synergistic action between the two, though more research is needed to fully clarify their individual and combined roles.