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Nutrition Diet: Understanding What are the side effects of sodium Phytate?

4 min read

Phytic acid, from which sodium phytate is derived, can make up to 1–7% of the dry weight of seeds and grains. Understanding what are the side effects of sodium phytate is crucial for those relying heavily on plant-based foods, as its mineral-binding properties can significantly influence nutrient absorption and overall dietary health.

Quick Summary

Sodium phytate is a salt of phytic acid found in many plant foods that impairs the absorption of key minerals like iron, zinc, and calcium, potentially leading to deficiencies in certain diets. However, this compound also offers notable health benefits, so a balanced perspective on its dietary effects is essential.

Key Points

  • Mineral Malabsorption: The primary side effect of dietary sodium phytate is the reduced absorption of minerals like iron, zinc, calcium, and magnesium due to its chelating action.

  • Risk for Specific Diets: Individuals on high-phytate, plant-based diets, such as vegetarians and vegans, are at higher risk for potential mineral deficiencies, particularly iron and zinc.

  • Preparation Mitigates Effects: Simple methods like soaking, sprouting, and fermenting grains and legumes significantly reduce phytate levels and enhance mineral bioavailability.

  • Beneficial Health Effects: Despite its 'antinutrient' label, phytic acid offers potent antioxidant, anti-inflammatory, and potentially anticancer properties, which benefit overall health.

  • Consider the Source and Dose: The side effects depend on the amount and form of phytate consumed. Moderate intake from a varied, balanced diet is generally not a concern, and benefits often outweigh the drawbacks.

In This Article

The Dual Nature of Sodium Phytate in Your Diet

Sodium phytate is the sodium salt of phytic acid, a compound found naturally in many plant-based foods, particularly whole grains, nuts, seeds, and legumes. In the context of diet, phytic acid is often labeled an “antinutrient” because of its strong chelating ability, which means it can bind to minerals in the digestive tract and inhibit their absorption by the body. For some, this effect can lead to nutritional concerns, while for others, especially those with balanced diets, the presence of phytates is not a problem. The potential side effects are influenced by various factors, including an individual's overall dietary pattern and methods of food preparation.

Adverse Side Effects on Mineral Absorption

The primary nutritional side effect associated with high consumption of phytic acid is reduced mineral absorption. Phytic acid molecules have a strong negative charge that attracts and binds to positively charged mineral ions, forming insoluble complexes that the body cannot absorb. This anti-nutrient effect can be a significant concern for certain minerals:

  • Iron: Phytate is a potent inhibitor of non-heme iron absorption, the type found in plant foods. This can put vegetarians and vegans, who rely on plant sources for iron, at a higher risk of developing iron deficiency anemia if not managed correctly.
  • Zinc: Zinc absorption is markedly affected by phytic acid. The issue is particularly notable in regions where cereal proteins are a primary food source, where zinc deficiency can be a public health concern.
  • Calcium and Magnesium: Phytic acid also binds with calcium and magnesium, reducing their bioavailability. While less pronounced than the effect on iron and zinc, it can still impact individuals with low intake or high nutritional needs. A high calcium-to-phytate ratio is often cited as a key indicator for adequate absorption.

Other Potential Dietary Effects and Concerns

Beyond mineral binding, research has explored other potential effects of phytic acid, though results are sometimes contradictory and depend on the form and concentration studied. In some animal studies, high doses of sodium phytate have been shown to impact growth performance and mineral homeostasis. Phytic acid can also interact with proteins and digestive enzymes like amylase, which might affect protein and starch digestibility, though the nutritional significance in humans is still under review. For most people following a varied and balanced diet, these effects are minimal and the health benefits often outweigh the drawbacks.

What About Sodium Phytate in Cosmetics and as a Supplement?

It is important to distinguish between dietary phytic acid from food and concentrated sodium phytate used in other applications. In cosmetics, where it is used as a chelating agent to bind metal ions, it is generally considered safe and non-comedogenic, meaning it won't clog pores. Adverse skin reactions are rare and mainly noted for individuals with high sensitivity. As for supplements, the effects can depend on the specific formulation. A study using sodium phytate supplements in rats suggested a potential impairment of calcium and phosphate reabsorption, highlighting the need to distinguish between phytate in its natural form (bound with minerals like calcium-magnesium) and isolated sodium salt.

The Health Benefits of Phytates

Despite its 'antinutrient' label, phytic acid offers a range of scientifically recognized health benefits, making it a valuable dietary component. These benefits include:

  • Antioxidant Properties: Phytic acid is a potent antioxidant that can chelate iron, which helps prevent the formation of harmful hydroxyl radicals that cause oxidative damage.
  • Cardiovascular Health: Some studies suggest phytate can help lower blood lipids like cholesterol and triglycerides, reducing the risk of heart disease.
  • Blood Sugar Control: Phytate may help regulate blood glucose response by slowing down the digestion of starch, which is beneficial for managing diabetes.
  • Kidney Stone Prevention: Evidence suggests that higher phytate intake is linked to a lower risk of forming kidney stones by inhibiting the crystallization of calcium salts.
  • Anticancer Potential: Phytic acid and its derivatives have shown potential anticancer effects in various studies, affecting cell signaling and growth pathways.

Mitigation Techniques for Phytate-Rich Foods

For those concerned about mineral absorption, particularly individuals on a vegetarian or vegan diet, several traditional food preparation methods can effectively reduce phytic acid content and enhance mineral bioavailability:

  • Soaking: Soaking legumes, grains, and nuts in water for several hours or overnight can significantly decrease their phytate levels.
  • Sprouting: Germination activates the enzyme phytase, which breaks down phytic acid.
  • Fermentation: The fermentation process, such as in making sourdough bread, utilizes beneficial bacteria to promote phytate breakdown.
  • Cooking: Standard cooking methods like boiling can also reduce phytic acid, with some reports suggesting reductions of up to 80%.

Comparison of Phytate in Different Food Preparations

Feature Unprocessed, High-Phytate Foods (e.g., raw nuts, uncooked beans) Prepared, Low-Phytate Foods (e.g., soaked/sprouted legumes, sourdough bread)
Mineral Bioavailability Low (Iron, zinc, calcium, magnesium are bound) High (Minerals are more readily available for absorption)
Enzyme Inhibition Potential for inhibition of digestive enzymes (amylase, pepsin) Minimal to no inhibition of digestive enzymes due to phytate breakdown
Nutritional Impact Concern for mineral deficiencies if diet is restricted or inadequate Generally enhanced nutritional value with higher mineral uptake
Digestibility Can be more difficult to digest for some individuals Improved digestibility and reduced potential for digestive discomfort

Conclusion

While the chelating properties of sodium phytate can reduce the absorption of certain minerals, its role in nutrition is complex and multifaceted. The 'side effects' of phytic acid are not significant for most individuals with a varied and balanced diet. For those at risk of mineral deficiencies, particularly vegetarians and vegans, simple preparation techniques like soaking, sprouting, and fermentation can effectively mitigate the anti-nutrient effect. Moreover, the compound possesses important health benefits, including antioxidant and anti-inflammatory properties, making a balanced intake from a diverse diet of nutrient-dense, plant-based foods a net positive for overall health. The key is understanding its role and adopting simple strategies to maximize nutritional value without forgoing these beneficial foods altogether.

Dietary Roles of Phytate and Phytase in Human Nutrition

Frequently Asked Questions

Sodium phytate is the salt of phytic acid, a natural compound found in the seeds, nuts, whole grains, and legumes of plants. It is often used as a food additive and in cosmetics due to its stabilizing properties.

While it can inhibit the absorption of minerals like iron, zinc, and calcium, this is rarely an issue for those on a balanced diet. Deficiencies are primarily a concern for individuals with high-phytate, restricted diets or in cases of malnutrition.

You can significantly reduce phytate content by soaking legumes and grains overnight, sprouting seeds and grains, or fermenting foods like sourdough bread. Cooking also helps break down phytates.

Yes, phytic acid is also a powerful antioxidant and has been linked to numerous health benefits. These include potential protection against certain cancers, heart disease, diabetes, and the formation of kidney stones.

Yes, for topical application, sodium phytate is considered safe for most skin types and is non-comedogenic. It is used as a chelating agent and antioxidant in cosmetics, though patch testing is recommended for sensitive skin.

No, phytic acid primarily affects the absorption of non-heme iron, which comes from plant sources. The heme iron found in meat and other animal products is not significantly affected.

No, avoiding all phytate-rich foods would mean giving up many nutrient-dense foods like whole grains and legumes. Instead, focus on preparation methods to reduce phytate levels and maintain a varied diet to ensure adequate nutrient intake.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.