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Nutrition Diet: What is the best way to take zinc?

4 min read

Over 17% of the global population is estimated to be at risk for zinc deficiency, underscoring the importance of proper intake. Whether you are considering supplements or boosting your diet, knowing what is the best way to take zinc can significantly impact its absorption and overall benefits for your health.

Quick Summary

Optimizing zinc intake involves prioritizing high-bioavailability food sources like meat and shellfish. For supplements, timing and form are crucial for absorption and reducing side effects. It is important to space zinc intake from other minerals and certain foods that can interfere with its efficacy.

Key Points

  • Prioritize Food Sources: The most natural and bioavailable zinc is found in animal products like oysters, meat, and shellfish.

  • Choose Absorbable Forms: For supplements, opt for highly-absorbed forms like zinc picolinate, citrate, or glycinate over less-absorbed options like zinc oxide.

  • Watch Your Timing: For optimal absorption, take zinc supplements on an empty stomach, but take with food if you experience nausea.

  • Avoid Mineral Conflicts: Do not take high-dose zinc, calcium, and iron supplements at the same time, as they compete for absorption; space them at least two hours apart.

  • Stay Within Limits: Limit total zinc intake to below the daily upper limit (40 mg for adults) to avoid potential side effects like copper deficiency.

  • Dietary Strategies for Plant-based Diets: Vegetarians and vegans can enhance absorption from legumes and grains by soaking, sprouting, or fermenting to reduce phytates.

  • Consult a Professional: Always talk to a healthcare provider before beginning high-dose zinc supplements, especially if you take other medications.

In This Article

Prioritizing dietary zinc for optimal absorption

For most individuals, the single most effective way to obtain zinc is through a well-balanced diet rich in zinc-containing foods. The zinc from animal-based foods, in particular, is more easily absorbed by the body due to the absence of inhibitory compounds found in some plant-based sources. While vegetarians and vegans can meet their needs, they may require careful planning to overcome absorption inhibitors.

Excellent dietary sources of zinc

  • Oysters: The richest source, with a 3-ounce serving providing a significant portion of the daily value.
  • Meat and Poultry: Red meat, particularly beef, is a robust source. Poultry, like turkey and chicken, also contributes substantial zinc.
  • Shellfish: Other shellfish such as crab, lobster, and mussels are excellent options.
  • Legumes: Beans, lentils, and chickpeas are good plant-based sources, although they contain phytates that can hinder absorption. Soaking and cooking can help reduce phytate content.
  • Nuts and Seeds: Cashews, pumpkin seeds, and hemp seeds are convenient and nutritious sources.
  • Dairy Products: Milk, cheese, and yogurt contain bioavailable zinc.
  • Whole Grains: Oats, quinoa, and brown rice provide zinc, but again, contain phytates.

When and how to take zinc supplements

While diet is the best primary source, supplements are necessary for those with deficiencies or specific health needs. For supplementation, the form of zinc and its timing are key considerations.

Timing for supplements

For maximum absorption, many experts recommend taking zinc supplements on an empty stomach, either 30 minutes before or two hours after a meal. However, some people experience nausea or stomach upset when taking zinc this way. If this occurs, taking the supplement with food is a better option, though it may slightly reduce absorption.

Avoiding common absorption inhibitors

Several factors can interfere with zinc absorption from supplements and diet:

  • Phytates: Found in plant-based foods like legumes, nuts, and whole grains, phytates bind to zinc and reduce its absorption.
  • High-dose minerals: Calcium and iron, when taken in high doses simultaneously, can compete with zinc for absorption. It is best to space these supplements out by at least two hours.
  • Certain Medications: Some antibiotics and arthritis medications can interact with zinc supplements, reducing their effectiveness. Always consult a healthcare provider regarding potential interactions.

Pairing zinc with absorption enhancers

  • Protein: A diet rich in protein, particularly animal protein, can enhance zinc absorption.
  • Amino Acids: Organic acids like citrate and picolinic acid, which bind to zinc in supplement form, are known to increase absorption.
  • Vitamin C: Some evidence suggests that combining vitamin C with zinc can provide synergistic immune benefits and improve absorption.

Forms of zinc supplements: a comparison

Not all zinc supplements are created equal. Different forms have varying bioavailability and potential for side effects. For example, zinc oxide, commonly used in topical products, has poor absorption when taken orally and is not recommended as a dietary supplement.

Form of Zinc Bioavailability Best For Potential Side Effects
Zinc Picolinate High Treating deficiency; general supplementation. Less likely to cause nausea than some other forms.
Zinc Citrate High General supplementation; less stomach upset than zinc sulfate. Can still cause nausea in sensitive individuals.
Zinc Glycinate Potentially very high Those seeking maximum absorption; minimal GI side effects. Generally well-tolerated.
Zinc Gluconate Good Common in lozenges for colds; general supplementation. Nausea and stomach irritation, especially on an empty stomach.
Zinc Acetate Good Often used in lozenges for colds; specific medical conditions like Wilson's disease. Can cause stomach upset and metallic taste.
Zinc Sulfate Lower than chelated forms Less expensive option; may require higher dose. Higher risk of stomach upset and nausea.

Long-term supplementation and safety

While zinc is essential, excessive long-term intake can be dangerous and lead to copper deficiency and a weakened immune system. The tolerable upper limit (UL) for adults is 40 mg per day from all sources, unless medically directed otherwise. Stick to the Recommended Dietary Allowance (RDA) of 11 mg for men and 8 mg for women, or slightly higher during pregnancy and lactation, unless a deficiency is confirmed by a healthcare professional. Nasal zinc sprays are explicitly discouraged due to the risk of permanent loss of smell.

Conclusion

The best way to take zinc is by first focusing on a diet rich in bioavailable sources like meat, shellfish, and dairy. For those who require supplementation, taking a highly absorbable form like zinc picolinate, citrate, or glycinate on an empty stomach can maximize its benefits, provided it doesn't cause gastric distress. If nausea is an issue, taking it with food is a viable alternative. Always be mindful of timing to avoid interactions with other minerals like calcium and iron. A comprehensive approach combining dietary diligence with a smart supplementation strategy, guided by a healthcare provider, will ensure you get the most out of this vital mineral for your health.

For more detailed information on mineral interactions, you can consult the National Institutes of Health.

Frequently Asked Questions

For maximum absorption, it is best to take zinc on an empty stomach (30 minutes before or 2 hours after a meal). However, if it causes stomach upset, taking it with food is a better alternative to minimize digestive discomfort.

Highly bioavailable forms of zinc include zinc picolinate, zinc citrate, and zinc glycinate. These are often better absorbed than zinc sulfate or zinc oxide, especially in supplement form.

Be cautious when taking zinc with other minerals like iron and calcium, as they can compete for absorption. It is best to take them at different times, separated by at least two hours.

Oysters are the richest source of zinc, followed by red meat, shellfish, and dairy products. Plant-based sources include legumes, nuts, seeds, and whole grains.

The Recommended Dietary Allowance (RDA) is 11 mg for adult men and 8 mg for adult women. Pregnant and breastfeeding women have slightly higher needs.

Excessive zinc intake (above 40 mg daily for adults) can cause side effects like nausea, vomiting, headaches, and abdominal cramps. Long-term high doses can lead to copper deficiency.

Some studies suggest that taking zinc lozenges or syrup at the first sign of a cold can help reduce its duration and severity. Nasal zinc sprays, however, are not recommended due to safety concerns.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.