The Normal Serum Magnesium Range
For most healthy adults, the normal range for serum magnesium is approximately 1.7 to 2.2 milligrams per deciliter (mg/dL), or 0.70 to 1.15 millimoles per liter (mmol/L). However, it is important to remember that these ranges can have slight variations depending on the laboratory and individual health factors. Healthcare professionals assess these results in conjunction with a person's medical history and symptoms.
Why a Blood Test Isn't the Whole Picture
While a serum magnesium test is the most common method, it has limitations because it measures only the magnesium in your blood—a small fraction of the body's total amount. The majority of magnesium (50% to 60%) is stored in bones, and most of the rest is within cells in soft tissues. This means that a person could have normal serum levels while having a total body magnesium deficit. For this reason, assessing true magnesium status can be challenging, and a comprehensive evaluation may require looking at a variety of factors, including diet, symptoms, and other specialized tests.
Hypomagnesemia: When Levels Are Too Low
Low magnesium, known as hypomagnesemia, is surprisingly common, with studies indicating a significant portion of the population may not consume the recommended daily amount through diet alone. The body works hard to prevent a deficiency, with the kidneys conserving the mineral when intake is low. However, chronic low intake or other health issues can lead to depletion. Initial symptoms can be subtle and include:
- Fatigue and weakness
- Loss of appetite
- Nausea and vomiting
- Personality changes
If the deficiency worsens, more severe symptoms can develop, including:
- Muscle cramps and spasms
- Tingling or numbness
- Abnormal heart rhythms (arrhythmias)
- Coronary spasms
- Seizures
Common causes of hypomagnesemia include:
- Dietary factors: Not eating enough magnesium-rich foods.
- Gastrointestinal issues: Conditions like Crohn's disease, celiac disease, or chronic diarrhea can impair absorption.
- Chronic alcoholism: Poor dietary intake and increased urinary excretion contribute to depletion.
- Certain medications: Long-term use of diuretics, proton pump inhibitors (PPIs), and some antibiotics can increase magnesium loss.
- Kidney disease: The kidneys' ability to retain magnesium can be impaired.
- Diabetes: High blood glucose can lead to increased urinary magnesium loss.
Hypermagnesemia: When Levels Are Too High
An excessively high level of magnesium (hypermagnesemia) is much rarer than a deficiency and is typically caused by impaired kidney function or over-supplementation, not from food alone. In a healthy individual, the kidneys effectively filter and excrete excess magnesium. Symptoms of hypermagnesemia usually appear when levels significantly exceed the normal range and can include:
- Nausea and vomiting
- Low blood pressure (hypotension)
- Facial flushing
- Lethargy and drowsiness
- Muscle weakness
- Impaired breathing
- Severely high levels can lead to irregular heartbeat, coma, and even cardiac arrest.
Increasing Magnesium Naturally
The best way to manage your magnesium levels is through a healthy diet. Many common foods are excellent sources of this essential mineral. Foods rich in magnesium:
- Leafy Greens: Spinach, Swiss chard.
- Nuts and Seeds: Pumpkin seeds, chia seeds, almonds, cashews.
- Legumes: Black beans, edamame, lentils.
- Whole Grains: Brown rice, whole wheat bread, shredded wheat cereal.
- Other Sources: Dark chocolate, avocados, tofu, bananas, and salmon.
Magnesium Supplementation and Absorption
If dietary changes are not enough, a healthcare provider may recommend a supplement. It's crucial to choose the right form, as some are absorbed more effectively than others. Excessive supplementation can lead to gastrointestinal side effects like diarrhea. For adults, the upper intake level (UL) for magnesium from supplements is 350 mg per day.
| Magnesium Form | Primary Use/Benefit | Absorption Rate | Common Side Effects | 
|---|---|---|---|
| Magnesium Glycinate | May improve sleep and anxiety. | Higher absorption; well-tolerated. | Generally mild; less likely to cause diarrhea. | 
| Magnesium Citrate | Often used as a laxative. | Higher absorption rate. | Can cause gastrointestinal distress and diarrhea. | 
| Magnesium Oxide | Common and inexpensive; used for heartburn/constipation. | Lower absorption rate. | Can cause laxative effects. | 
| Magnesium Lactate | Often used to treat deficiency. | Higher absorption rate; well-tolerated. | Minimal side effects; good for sensitive individuals. | 
| Magnesium Chloride | Often used topically or in mineral water. | Well-absorbed. | Can cause diarrhea in some individuals. | 
Understanding Your Magnesium Test Results
If your doctor has ordered a magnesium test, it is likely because you have symptoms of a possible imbalance or a pre-existing condition that puts you at risk, such as kidney disease, diabetes, or alcoholism. While a simple serum test is a starting point, other methods may be used to get a more accurate picture of your overall magnesium status, including:
- Red Blood Cell (RBC) Magnesium Test: Measures magnesium within red blood cells, which can provide a better indicator of cellular magnesium stores.
- 24-Hour Urine Test: Measures how much magnesium your kidneys excrete over a day.
- Magnesium Loading Test: Evaluates how the body absorbs and retains a dose of magnesium, offering insights into whole-body status.
Always discuss any test results with your healthcare provider. They will provide the most accurate interpretation based on your health history and individual circumstances. For general information on nutrition, the National Institutes of Health's Office of Dietary Supplements offers extensive resources.
Conclusion
Understanding what range your magnesium should be starts with knowing the normal serum levels, but it's equally important to recognize the limitations of a single test. The body's magnesium is tightly regulated, but factors like diet, chronic disease, and medication can disrupt this balance, leading to either deficiency or, less commonly, excess. By consuming a diet rich in magnesium-containing foods and consulting with a healthcare professional about appropriate supplementation or specialized testing when necessary, individuals can effectively manage their magnesium status and support their overall health and well-being.