What is another name for iron polysaccharide?
The most common alternative name for iron polysaccharide is polysaccharide-iron complex. This term refers to the same oral iron supplement, and the terms are often used interchangeably by healthcare providers and in medical literature. While polysaccharide-iron complex is the precise chemical name, iron polysaccharide is a simpler, more common generic designation.
Generic and brand names
In addition to its main alternative name, iron polysaccharide is sold under numerous brand names, which can sometimes lead to confusion. Some of the most recognized brand names in the United States and internationally include:
- Niferex: Available in capsule and elixir forms.
- Ferrex-150: A popular brand that comes in capsule form.
- NovaFerrum: Available in various strengths, including pediatric drops.
- Nu-Iron: Another common over-the-counter option.
- Hytinic: Mentioned in several pharmaceutical references as a brand containing polysaccharide iron.
- Poly-Iron: A straightforward brand name indicating the product contains iron polysaccharide.
The chemistry of polysaccharide-iron complex
To understand why it's called a 'complex,' it's helpful to know how the supplement is structured. Unlike older, simpler iron salts (like ferrous sulfate), polysaccharide-iron complex contains ferric iron ($Fe^{3+}$) atoms that are bound to large carbohydrate molecules called polysaccharides. This unique molecular structure is what gives it different properties compared to other iron supplements. The chelation of the iron by the polysaccharide makes it more stable in the gastrointestinal (GI) tract and less reactive with other substances, which is thought to be the reason for its reduced side effects.
Iron polysaccharide vs. other oral iron supplements
Iron polysaccharide is often a preferred option for patients who experience significant gastrointestinal side effects from traditional iron salts. Here is a comparison with the most common and inexpensive alternative, ferrous sulfate.
| Feature | Polysaccharide-Iron Complex (PIC) | Ferrous Sulfate |
|---|---|---|
| Elemental Iron | Typically contains a higher concentration of elemental iron per dose, but absorption can vary. | Standard elemental iron content, often less than PIC per dose. |
| Gastrointestinal (GI) Side Effects | Significantly fewer reported GI side effects, such as nausea, constipation, and stomach upset. | Higher incidence of GI side effects, a common reason for non-compliance. |
| Cost | Generally more expensive due to the more advanced formulation. | Relatively inexpensive and widely available. |
| Absorption | Absorbed less efficiently than ferrous sulfate in some studies, but often sufficient for treating deficiency. | Considered to have high absorption, especially when taken on an empty stomach. |
The choice between an iron polysaccharide complex and a ferrous salt often depends on a patient's tolerance. For those who cannot tolerate the GI discomfort caused by ferrous sulfate, the polysaccharide version provides a viable and often necessary alternative for successful treatment of anemia.
Proper usage and potential side effects
Dosage and administration
Oral iron supplements should always be taken under the guidance of a healthcare professional. Dosing for polysaccharide-iron complex, like other iron supplements, is usually based on the severity of the deficiency. It is typically recommended to take the supplement on an empty stomach for better absorption, though it can be taken with food if stomach upset occurs. This flexibility is a major benefit for many users.
Potential side effects
While generally well-tolerated, iron polysaccharide can cause some side effects, although typically less severe than other iron forms. Common side effects include:
- Dark-colored or tarry stools
- Upset stomach or mild nausea
- Constipation or diarrhea
It is crucial to be aware of the risk of iron overdose, which can be serious, particularly for young children. All iron supplements should be stored safely out of reach of children. Symptoms of an overdose may include fever, vomiting, stomach pain, and rapid heart rate.
The importance of iron supplements
Iron is an essential mineral required for many bodily functions, most notably the production of hemoglobin, the protein in red blood cells that carries oxygen throughout the body. When iron levels are insufficient, iron deficiency anemia can occur, leading to symptoms like fatigue, weakness, shortness of breath, and pale skin. The use of iron supplements, such as polysaccharide-iron complex, helps to replenish these low iron stores and resolve the symptoms of anemia.
For more in-depth information on the efficacy and safety of polysaccharide iron complexes, see this study published by the National Institutes of Health.
Conclusion
In summary, another name for iron polysaccharide is polysaccharide-iron complex. This supplement provides an effective oral treatment for iron deficiency and is known for being gentler on the stomach than older forms like ferrous sulfate. Due to its chelated structure, it minimizes the gastrointestinal side effects that often cause patients to discontinue treatment. For individuals with iron deficiency anemia who struggle with standard iron salts, exploring polysaccharide-iron complex options, such as the various brands available, can be a highly beneficial course of action under a doctor's supervision.
