The Dominance of Carbazole Alkaloids
Carbazole alkaloids are a significant group of nitrogen-containing compounds in curry leaves and are considered primary bioactive constituents. These compounds are associated with several medicinal properties, including potential anticancer, hepatoprotective, and antimicrobial effects. Key carbazole alkaloids identified in curry leaves include mahanimbine, known for potential antidiabetic and anticancer properties, girinimbine, noted for antioxidant and anti-inflammatory activities, mahanine, linked to inducing apoptosis in cancer cells and antioxidant effects, and murrayanine and murrayacine, which possess antibacterial and antifungal properties.
The Volatile Compounds of Essential Oils
The distinctive fragrance of curry leaves stems from their essential oils, a mix of volatile compounds that varies based on factors like origin and maturity. Major components include various terpenoids and monoterpenes. α-Pinene and β-Pinene contribute to the characteristic aroma, while sabinene adds a woody, spicy note. β-Caryophyllene provides a peppery and woody scent. Linalool offers a floral aroma, and elemol is another significant sesquiterpene alcohol in some varieties.
Flavonoids and Phenolic Compounds
Curry leaves are rich in phenolic compounds, potent phytonutrients known for their antioxidant properties that help combat oxidative stress. Notable flavonoids include quercetin, recognized for antioxidant and anti-inflammatory effects, myricetin, offering significant antioxidant and potential anticancer activities, and rutin, which also contributes to the plant's antioxidant capacity. Other phenolic acids like gallic acid, ferulic acid, and vanillic acid further enhance the leaves' ability to scavenge free radicals.
Other Chemical and Nutritional Components
Beyond the primary bioactive compounds, curry leaves provide essential nutrients. Per 100 grams, they offer carbohydrates, fiber, and protein, with low fat content. They are a good source of provitamin A (beta-carotene), vitamin C, and B vitamins, as well as minerals like calcium, phosphorus, iron, and magnesium. The seeds contain furocoumarins such as xanthotoxin and isobyakangelicol, and the leaves also contain oxalic acid and resin.
Comparison of Fresh vs. Dried Curry Leaves
Both fresh and dried curry leaves contain similar compounds, but their properties differ. Drying impacts the volatile oil content, altering the flavor and aroma. However, the nutritional and phenolic content often remains substantial.
| Feature | Fresh Curry Leaves | Dried Curry Leaf Powder | 
|---|---|---|
| Aroma | Pungent, intense, and fresh | Less intense, more subtle | 
| Moisture Content | Higher (approx. 63.8g/100g) | Lower (approx. 5.86g/100g) | 
| Volatile Oils | Higher concentration and complexity | Reduced concentration due to evaporation | 
| Nutritional Density | Lower on a per-gram basis | Higher due to reduced water content | 
| Culinary Use | Ideal for tempering and fresh dishes | Excellent for spice blends and flavoring powdered foods | 
Conclusion: A Complex Phytochemical Profile
Curry leaves possess a complex chemical profile beyond their culinary use. The combination of carbazole alkaloids, terpenoid-rich essential oils, flavonoids, and other phenolic compounds forms the basis for their traditional medicinal applications. The specific composition can vary based on genetics and environment, contributing to a broad range of reported biological activities including antioxidant, antimicrobial, and anti-inflammatory effects. Ongoing research continues to explore the therapeutic potential of these compounds. For further details, scientific reviews on the plant's properties are available.