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What are common limiting amino acids?

3 min read

According to the European Union's Knowledge for Policy portal, four amino acids are most likely to be limiting in a diet: lysine, methionine, threonine, and tryptophan. A limiting amino acid is an essential amino acid present in a food source in an insufficient quantity to support optimal protein synthesis. Understanding these deficiencies is crucial for planning a balanced diet.

Quick Summary

Limiting amino acids are essential amino acids in short supply within a protein source, hindering the body's overall protein synthesis. This guide details the most common limiting amino acids and provides strategies for ensuring adequate intake, especially for those on plant-based diets.

Key Points

  • Essential Amino Acids: Your body needs nine essential amino acids from your diet, as it cannot produce them itself.

  • The Limiting Factor: A limiting amino acid is the essential amino acid in shortest supply within a specific food, capping the body's ability to synthesize new proteins.

  • Common Deficiencies: Lysine is often limiting in grains, while methionine is typically limiting in legumes.

  • Complementary Proteins: Combining incomplete plant proteins, like grains and legumes, ensures you get all essential amino acids.

  • No Meal Pairing Necessary: You do not need to pair complementary proteins in the same meal; a varied diet over the course of a day is sufficient.

  • Plant-Based Success: Plant-based diets can easily meet all amino acid needs by incorporating a variety of different plant protein sources.

In This Article

Understanding the Limiting Amino Acid Concept

To understand what common limiting amino acids are, one must first grasp the concept of essential amino acids. The human body requires 20 different amino acids to function correctly, but it can only produce 11 of them. The other nine, known as essential amino acids (EAAs), must be obtained through diet. The limiting amino acid is the essential amino acid found in the lowest concentration relative to the body’s needs within a particular food source. This concept is often explained using the “barrel” analogy, where the shortest stave of the barrel (the limiting amino acid) determines how much water (protein) the barrel can hold. Without a sufficient supply of all EAAs, protein synthesis is limited to the level of the least available amino acid, regardless of how abundant the others are.

Common Limiting Amino Acids and Their Sources

The specific amino acid that is limiting varies depending on the food source. While a complete protein source like meat or eggs contains all essential amino acids in adequate proportions, many plant-based proteins are considered incomplete because they are deficient in one or more.

  • Lysine: This is a key limiting amino acid in cereal grains like wheat, rice, and corn. For vegans and vegetarians, pairing grains with lysine-rich foods is essential for a balanced diet.
  • Methionine: Soybeans and most legumes, including beans and peas, are often low in the sulfur-containing amino acids, methionine and cysteine. This is a common consideration for those following plant-heavy or vegan diets.
  • Threonine: Found to be a limiting amino acid in some grains and legume products, threonine is necessary for forming structural proteins like collagen and elastin.
  • Tryptophan: Some sources indicate that tryptophan can be limiting in plant-based diets, though it is often found in nuts, seeds, and tofu.

Limiting Amino Acids in Animal vs. Plant Protein

Animal proteins are typically complete, providing all essential amino acids in sufficient amounts, while plant proteins are often incomplete, requiring a variety of sources for complete intake.

Achieving Complete Protein Through Complementary Foods

While historically thought to require combining in the same meal, consuming a variety of plant-based proteins throughout the day is sufficient to meet amino acid needs. Complementary pairings include grains with legumes (e.g., rice and beans), nuts/seeds with legumes (e.g., hummus), and vegetables with grains or nuts/seeds.

The Role of Limiting Amino Acids in Protein Synthesis

Protein synthesis requires all essential amino acids simultaneously. A limiting amino acid restricts this process, impacting the body's ability to build and repair tissues.

Comparison of Common Limiting Amino Acids in Food Sources

Food Category Primary Limiting Amino Acid(s) Complementary Food Sources Examples of Complementary Meals
Grains (e.g., wheat, rice, corn) Lysine, Threonine Legumes, soy, quinoa Rice and beans, corn tortilla with beans, lentils with whole wheat bread
Legumes (e.g., beans, lentils, peas) Methionine (+ Cysteine) Grains, nuts, seeds Hummus (chickpeas and sesame), peanut butter on whole wheat bread
Nuts & Seeds Lysine Legumes, soy Trail mix with nuts and roasted chickpeas
Vegetables Methionine Grains, nuts, seeds Tofu and rice with mixed veggies

Conclusion: Strategic Eating for Optimal Health

Understanding common limiting amino acids is crucial for a balanced diet. While animal products provide complete proteins, plant-based diets can easily achieve this by combining various plant foods throughout the day, ensuring a steady supply of all essential amino acids for vital bodily functions. Dietary diversity is key to avoiding deficiencies and maintaining health. For more information on balanced vegan diets, the National Institutes of Health is a valuable resource.

Frequently Asked Questions

A limiting amino acid is an essential amino acid that is found in the lowest concentration relative to the body's needs within a particular food source, restricting the body's overall rate of protein synthesis.

The essential amino acid lysine is most commonly limiting in cereal grains such as wheat, corn, and rice.

Methionine is the amino acid typically found in short supply in legumes and other plant proteins like soybeans and peanuts.

No, it is not necessary to combine complementary proteins in the same meal. As long as a variety of protein sources are consumed throughout the day, the body can acquire all the essential amino acids it needs.

Examples include eating rice and beans, hummus with pita bread (chickpeas and wheat), or a peanut butter sandwich on whole wheat bread. The combination helps to cover the limiting amino acids in each food source.

Animal proteins like meat, eggs, and dairy are generally considered complete proteins, meaning they contain all nine essential amino acids in sufficient amounts and are not typically limited.

By eating a varied diet that includes a wide range of plant-based protein sources, such as combining grains, legumes, nuts, and seeds, vegans and vegetarians can easily meet all their essential amino acid needs over the course of a day.

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.