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What are the side effects of brominated vegetable oil?

4 min read

According to the U.S. Food and Drug Administration (FDA), recent studies have shown that brominated vegetable oil (BVO) is no longer considered safe for consumption. This decision, which has led to a nationwide ban effective August 2025, highlights the potential health risks and significant side effects of this once-common food additive.

Quick Summary

Brominated vegetable oil (BVO) can cause thyroid disruption and neurological symptoms, with risks increasing from long-term accumulation. The FDA has banned its use, citing evidence of adverse health effects discovered through recent animal studies, leading companies to reformulate beverages.

Key Points

  • Neurological damage: BVO consumption can lead to bromine accumulation in the nervous system, potentially causing headaches, memory loss, fatigue, and impaired coordination.

  • Thyroid interference: Bromine in BVO competes with iodine, disrupting thyroid function and potentially causing hormonal imbalances.

  • Organ accumulation: Studies have shown that brominated fats from BVO build up in body fat, as well as in the liver, heart, and brain tissue over time.

  • Banned globally: Following years of mounting health concerns, regulatory bodies in the UK, Europe, Japan, Canada, and the U.S. have banned or are phasing out the use of BVO.

  • Safer alternatives available: Food manufacturers have successfully replaced BVO with safe emulsifiers like sucrose acetate isobutyrate (SAIB) and glycerol ester of wood rosin (GEWR).

In This Article

What is Brominated Vegetable Oil?

Brominated vegetable oil, commonly abbreviated as BVO, is a vegetable oil modified with bromine. It has historically been used by the food and beverage industry as an emulsifier, primarily in citrus-flavored beverages like sodas and sports drinks. Its purpose is to prevent the citrus flavoring oils from separating from the water-based beverage, keeping the mixture uniform and preventing the flavor from floating to the top. The resulting solution has a stable, cloudy appearance that is consistent across the product shelf life. While BVO was useful for this technical function, decades of regulatory and scientific scrutiny have uncovered a range of concerning health effects associated with its consumption.

A History of Regulation and Scrutiny

BVO's regulatory journey is long and complex. Initially classified as 'generally recognized as safe' (GRAS) by the FDA in the 1950s, its status was revoked in 1970 after preliminary toxicity concerns emerged. Following manufacturer petitions, the FDA allowed BVO's continued use on an interim basis in limited quantities while further studies were conducted. Many international bodies acted more quickly, with the United Kingdom banning it in the 1970s, Europe banning it in 2008, and Japan following in 2010. Under mounting consumer pressure and new scientific evidence, major beverage brands began phasing out BVO voluntarily years ago. In 2023, California became the first U.S. state to ban BVO, prompting further federal action. The FDA ultimately finalized a federal ban in July 2024, effective August 2025, after concluding it is no longer safe for use.

Documented Side Effects of Brominated Vegetable Oil

Health concerns related to BVO are primarily associated with the accumulation of bromine in the body, which can interfere with essential bodily functions. Animal and case studies have linked BVO consumption to several adverse health outcomes, particularly with high, long-term exposure.

Neurological and Nervous System Damage

One of the most documented side effects involves the central nervous system. Bromine can accumulate in body fat and brain tissue, leading to neurological symptoms. Reported effects include headaches, fatigue, memory loss, and loss of coordination. A specific case involved a man who consumed excessive amounts of BVO-containing soda daily, eventually suffering from severe neurological issues like tremors and memory loss that required medical intervention.

Thyroid Function Disruption

Bromine's chemical similarity to iodine is a major cause for concern. When ingested, bromine can compete with and interfere with iodine absorption by the thyroid gland, which is crucial for producing vital hormones. This disruption can lead to a hormonal imbalance that affects metabolism, energy levels, mood, and reproductive health. Animal studies have shown increased levels of bromide in the blood and impacts on thyroid hormone levels following BVO exposure.

Accumulation in Organs and Tissue

Research indicates that brominated fat molecules from BVO can build up in body fat, as well as vital organs including the liver, heart, lungs, and brain. While moderate intake may not cause immediate harm, this long-term accumulation poses a significant health risk, justifying the FDA's decision to ban the additive.

Bromism and Other Irritation

Chronic, high-level exposure to bromine can lead to a condition known as bromism, which is characterized by symptoms such as fatigue, severe headaches, and memory loss. Additionally, some individuals may experience skin irritation, rashes, or irritation of mucous membranes (the lining of the nose, mouth, and stomach) from consuming products containing BVO.

Safer Alternatives to BVO

Fortunately, food manufacturers have already transitioned to safer, well-vetted alternatives to achieve the same emulsifying effect without the associated health risks. These alternatives are considered safe by regulatory bodies and are now widely used in beverages around the world.

Comparison of BVO vs. Alternatives

Feature Brominated Vegetable Oil (BVO) Sucrose Acetate Isobutyrate (SAIB) Glycerol Ester of Wood Rosin (GEWR)
Function Emulsifier, density adjusting agent Emulsifier, clouding agent Emulsifier, stabilizer
Health Concerns Thyroid disruption, neurological damage, tissue accumulation None at currently approved levels None at currently approved levels
Ingredient Basis Vegetable oil reacted with bromine Sucrose, acetic acid, and isobutyric anhydride Derived from pine trees (wood rosin)
Regulatory Status (US) Banned effective August 2025 Approved for food use Approved for food use
Regulatory Status (EU) Banned since 2008 Approved for food use Approved for food use

Common Safer Emulsifiers

  • Sucrose Acetate Isobutyrate (SAIB): A synthetic compound that effectively stabilizes emulsions in beverages and is widely approved for food use.
  • Glycerol Ester of Wood Rosin (GEWR): Derived from pine trees, this additive works well as a stabilizer in citrus-flavored products.
  • Gum Arabic: A natural gum sourced from the acacia tree, known for its emulsifying properties and smooth mouthfeel.
  • Modified Cellulose: A plant-derived polysaccharide that provides excellent stability and is non-toxic.

Conclusion

The extensive health risks associated with brominated vegetable oil, particularly its potential to disrupt thyroid function and cause neurological issues, led to its removal from the U.S. food supply. The FDA's recent final rule banning BVO follows decades of scientific research and public health advocacy, culminating in a significant victory for food safety. With a variety of safe and effective alternatives now in use, consumers can rest assured that this harmful additive is being phased out of popular beverages. To avoid BVO and other potentially harmful additives, checking ingredient labels and opting for whole, fresh foods remains the most reliable strategy.

Authoritative Source

EWG: FDA finds brominated vegetable oil no longer safe for use in food

Frequently Asked Questions

BVO is considered dangerous because its bromine content can accumulate in body tissues over time, leading to potential health problems such as neurological damage and disruption of the thyroid's hormonal balance.

Bromism is a condition caused by excessive, long-term exposure to bromine, which was a component of BVO. It is characterized by symptoms including fatigue, headaches, and memory loss.

While moderate consumption of BVO was less likely to cause severe, immediate harm, the primary concern was the long-term accumulation of brominated fats in the body, which was linked to health issues over time.

BVO was most commonly found in citrus-flavored beverages, including some sodas, sports drinks, and fruit-flavored drinks. However, most major brands voluntarily removed the additive years ago.

The FDA's ban took effect in August 2024, but companies have until August 2025 to comply and deplete their inventory. This means some older stock containing BVO may still be on shelves, and consumers should check ingredient labels.

Manufacturers have switched to safer alternatives like sucrose acetate isobutyrate (SAIB) and glycerol ester of wood rosin (ester gum), which serve the same emulsifying purpose without the health risks.

The best way to avoid BVO is to check the ingredient list on packaged drinks, especially citrus-flavored ones. Choosing fresh, whole foods and water is also an effective way to minimize exposure to additives.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.