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What are the sources of CLA?

3 min read

The average American diet supplies a relatively low amount of naturally occurring conjugated linoleic acid (CLA), typically between 15 and 174 mg daily. This essential omega-6 fatty acid is a component of healthy foods but is also widely available through dietary supplements for those seeking higher intake.

Quick Summary

An overview of CLA sources, focusing on natural dietary options from ruminant animals like grass-fed cattle and sheep, as well as plant-based sources and supplements derived from vegetable oils. Explores differences between natural and synthetic CLA forms.

Key Points

  • Ruminant Products are the Primary Natural Source: Meat and dairy from animals like cattle, sheep, and goats are the main natural dietary sources of CLA.

  • Grass-Fed is Key for Natural CLA: Animals raised on pasture have significantly higher CLA content in their meat and milk compared to grain-fed livestock.

  • Dairy Products Vary in CLA Content: The amount of CLA in dairy items like milk, cheese, and yogurt can vary depending on the animal's diet and processing methods.

  • Supplements are Derived from Plants: Most commercial CLA supplements are synthetically produced from vegetable oils, such as safflower oil, and have a different isomer profile than natural CLA.

  • Natural vs. Synthetic Isomers Differ: Natural CLA is mostly the c9,t11 isomer, while supplements typically provide a roughly 50:50 mixture of c9,t11 and t10,c12 isomers.

  • Cooking Increases CLA in Meat: The total CLA content in beef can increase during cooking due to moisture loss and the stability of CLA isomers at higher temperatures.

  • Limited Plant-Based Dietary Sources: Plant-based oils contain very low amounts of CLA, though they are a source of linoleic acid that gut bacteria can convert to CLA.

  • Higher Doses with Supplements: To achieve the higher dosage levels used in some research studies, supplementation is required as natural dietary intake is typically low.

In This Article

Ruminant-Derived Foods: The Primary Natural Sources

The main dietary sources of CLA are meat and dairy products from ruminant animals such as cows, sheep, and goats. These animals produce CLA through a process called biohydrogenation, performed by bacteria in their digestive systems. The amount of CLA in these foods is heavily influenced by the animal's diet, with grass-fed animals producing significantly higher concentrations than those fed a grain-based diet. The most common isomer found in naturally derived CLA is cis-9, trans-11.

Dairy Products

Dairy products represent a significant source of natural CLA for many people. The concentration can vary widely based on the animal's diet and the product itself. Products from grass-fed cows, sheep, and goats tend to have the highest levels. Cooking and processing methods can also influence the final CLA content, with some high-temperature processes potentially causing a slight increase.

  • Cheese: Particularly aged cheeses, which can see slightly elevated levels due to the fermentation process.
  • Butter: A concentrated source of milk fat, providing notable levels of CLA.
  • Yogurt and Fermented Milk: Lactic acid bacteria used in fermentation can enhance CLA production.
  • Milk: The CLA content of milk is affected by seasonal variations and the animal's pasture access.

Meats from Ruminants

Meat from ruminants, especially grass-fed, is another key source of naturally occurring CLA. Lamb, in particular, often has higher concentrations compared to beef. The fat content and cooking method can also affect the final amount available for consumption.

  • Beef: Grass-fed beef contains substantially higher CLA levels than grain-fed varieties.
  • Lamb: Often cited as one of the richest meat sources of CLA.
  • Veal: Also contains CLA, though typically in lower concentrations than beef and lamb.

Synthetic and Plant-Based Sources of CLA

For those who do not consume animal products or are seeking a higher concentration of CLA, other sources are available. These sources differ significantly from their natural counterparts in terms of isomer ratio and production methods.

CLA Supplements

Most CLA supplements on the market are not derived from animal fats but are chemically produced from linoleic acid found in vegetable oils. Safflower oil is a common starting material for this process. The resulting supplement contains a roughly 50:50 mix of the cis-9, trans-11 (c9,t11) and trans-10, cis-12 (t10,c12) isomers, which is different from the ratio found in nature.

Plant-Based Oils

While animal products are the richest source, some plant-based oils contain linoleic acid that can be converted into CLA by gut bacteria. However, the CLA content in vegetable oils themselves is very low. Oils high in linoleic acid include:

  • Sunflower oil
  • Safflower oil
  • Corn oil

Comparison of Natural vs. Synthetic CLA

Property Natural (Ruminant) CLA Synthetic (Supplement) CLA
Source Ruminant meat and dairy Vegetable oils (e.g., safflower)
Isomer Ratio Dominated by the c9,t11 isomer (80–90%) Approximately a 50:50 mix of c9,t11 and t10,c12 isomers
Availability Dependent on animal's diet (higher in grass-fed) Consistent and concentrated dosage in capsules or softgels
Intake Level Average dietary intake is typically low Supplemental intake can be much higher (e.g., 3–6 grams daily)
Potential Health Effects Associated with beneficial health outcomes in observational studies Research has shown mixed results, and high doses may have potential side effects
Consumer Perception Often viewed as more beneficial due to natural origin Offers convenience and higher dosage, but isomer differences exist

Conclusion

Conjugated Linoleic Acid (CLA) is primarily obtained from the fat of ruminant animals, such as dairy products and meat from grass-fed cattle and sheep. These natural sources contain a high proportion of the cis-9, trans-11 isomer, which many studies have explored for its health benefits. For those with dietary restrictions or seeking higher doses, CLA supplements are manufactured from vegetable oils, typically safflower oil, resulting in a different isomer ratio. While effective, the supplemental forms should be approached with an understanding of their compositional difference from natural food sources. Ultimately, incorporating a variety of naturally CLA-rich foods, particularly grass-fed options, is an excellent way to boost your dietary intake of this beneficial fatty acid.

For more detailed information on CLA's health effects and its different isomers, you can refer to the extensive review published in Nutrients.

Frequently Asked Questions

CLA, or conjugated linoleic acid, is an omega-6 polyunsaturated fatty acid found naturally in the meat and dairy products of ruminant animals. It is also available in supplement form, typically derived from vegetable oils.

Yes, grass-fed beef contains significantly higher concentrations of CLA—often 300–500% more—than beef from animals fed a grain-based diet. The animals' pasture-based diet provides the necessary precursors for CLA synthesis.

While natural dietary sources of CLA are primarily animal-based, trace amounts can be produced by gut bacteria from linoleic acid in plants. Some vegetable oils, such as safflower and sunflower oil, are rich in linoleic acid and are also used to create synthetic CLA supplements.

The CLA in supplements is usually chemically altered from vegetable oil, resulting in a different ratio of isomers (approximately 50% c9,t11 and 50% t10,c12) compared to natural CLA, which is predominantly the c9,t11 isomer (80–90%).

Yes, consuming more dairy products from ruminants, like cheese and butter, will increase your dietary CLA intake. For the highest levels, opt for dairy from grass-fed sources, as the animal's diet directly impacts the CLA content in milk fat.

Cooking meat can increase its total CLA concentration, largely because of moisture loss during the process. Studies show CLA isomers are stable under thermal processing, so cooking does not negatively alter the CLA content.

No, fish and poultry are not significant dietary sources of CLA, as they lack the ruminant digestive system necessary for natural CLA synthesis. Their CLA levels are typically very low compared to those found in beef and lamb.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.