Skip to content

What can cause loss of appetite and taste?

4 min read

According to the National Institute on Deafness and Other Communication Disorders (NIDCD), millions of Americans experience a chemosensory disorder affecting their sense of taste or smell, which often results in a loss of appetite. Understanding the root cause is the first step toward effective management and recovery.

Quick Summary

Loss of appetite and taste can stem from various causes, including infections like the common cold or COVID-19, certain medications, chronic illnesses, aging, and nutritional deficiencies. The interconnectedness of taste and smell means issues with one can affect the other, significantly impacting food enjoyment and intake.

Key Points

  • Infections are common culprits: Viral and bacterial infections like the common cold, flu, and COVID-19 frequently cause temporary loss of taste and appetite due to nasal congestion.

  • Medications can interfere: Numerous medications, including antibiotics, blood pressure drugs, and chemotherapy agents, are known to alter or diminish taste and appetite as a side effect.

  • Senses of taste and smell are linked: Your perception of flavor relies heavily on your sense of smell, so an issue with one often affects the other, making food unappealing.

  • Chronic diseases are a factor: Underlying health conditions such as diabetes, liver or kidney disease, and neurological disorders can cause persistent changes in appetite and taste.

  • Deficiencies play a role: A lack of essential nutrients, particularly zinc and Vitamin B12, can directly impact the function of your taste buds.

  • Aging affects senses: As a natural part of the aging process, a gradual decline in the number and function of taste buds can lead to reduced taste sensitivity, especially for sweet and salty flavors.

  • Seek medical advice for persistence: While temporary loss is common, persistent changes in appetite and taste should be evaluated by a doctor to rule out serious underlying causes.

In This Article

Infections and Viral Illnesses

One of the most common reasons for a sudden loss of appetite and taste is an infection. Many temporary illnesses cause inflammation and congestion in the nasal passages, which directly impacts your sense of smell, and in turn, your sense of taste.

The Link Between Smell and Taste

Your sense of taste is not just your tongue distinguishing sweet, sour, salty, bitter, and umami. It relies heavily on your sense of smell to perceive the complex nuances of flavor. When an infection blocks your olfactory sensory neurons, you may perceive food as bland or tasteless, leading to a reduced desire to eat.

Common culprits include:

  • Upper Respiratory Infections: The common cold, flu, and sinus infections often cause a diminished sense of taste and smell due to nasal congestion.
  • COVID-19: This virus is particularly well-known for causing a temporary or sometimes prolonged loss of taste (ageusia) and smell (anosmia).
  • Strep Throat: This bacterial infection can cause inflammation that affects your perception of taste.

Medications and Chemical Exposure

Many prescription and over-the-counter drugs list altered taste and decreased appetite as potential side effects. This can be due to the drug altering taste receptors, changing saliva composition, or interfering with nerve signals to the brain.

Medications that can cause taste disturbances:

  • Antibiotics: Certain antibiotics, such as ampicillin, metronidazole, and clarithromycin, are common offenders that can cause a metallic or unpleasant taste.
  • Blood Pressure Medications: ACE inhibitors like captopril and enalapril are known to alter taste.
  • Chemotherapy Drugs: Cancer treatments often damage rapidly dividing taste receptor cells, leading to severe taste changes.
  • Antidepressants: Some SSRIs and other antidepressants can cause a dry mouth or alter taste perception.

Beyond medicine, exposure to certain chemicals or toxins can also be a factor. For example, exposure to insecticides, paint solvents, or heavy metals can affect the senses. Smoking tobacco is another well-documented cause of dulled taste and appetite due to damage to taste buds. Quitting smoking can often lead to a restoration of these senses within 48 hours for some individuals.

Chronic Medical Conditions

Persistent loss of appetite and taste can be a symptom of a more serious, chronic medical condition. In these cases, the symptoms are often accompanied by other signs and may require a more thorough medical investigation.

Neurological Disorders

  • Alzheimer's and Parkinson's Disease: A diminished sense of smell can be an early indicator of neurodegenerative diseases.
  • Multiple Sclerosis (MS): This condition can damage the nerves involved in taste and smell.
  • Head Injury: Trauma to the head can damage the olfactory nerve, which carries scent information to the brain, directly affecting taste and appetite.

Other Systemic Diseases

  • Diabetes: Poorly managed blood sugar levels can affect nerves and lead to altered taste perception.
  • Kidney or Liver Disease: Advanced conditions can cause a buildup of toxins in the body, leading to a metallic taste and loss of appetite.
  • Cancer: Cancers affecting the head, neck, or digestive system, as well as their treatments, can severely impact appetite and taste.
  • Hypothyroidism: An underactive thyroid can slow metabolism and reduce hunger signals.

Nutritional Deficiencies and Lifestyle Factors

Certain deficiencies can impair the function of taste receptors and nerves. A lack of proper nutrients can cause a cycle where poor appetite leads to further deficiencies.

  • Zinc Deficiency: Zinc is crucial for taste bud development and function. A deficiency can directly cause a loss or distortion of taste.
  • Vitamin B12 Deficiency: Low levels of B12 have been linked to a decline in taste and smell function.
  • Aging: As people grow older, their total number of taste buds can decrease, and the remaining ones may not be as sharp, often affecting the ability to taste sweet and salty flavors first.

Comparison: Temporary vs. Chronic Causes

Feature Temporary Causes (e.g., Cold, Flu) Chronic Causes (e.g., Diabetes, Cancer)
Onset Often sudden, coinciding with the illness. Can be gradual over weeks, months, or years.
Duration Typically resolves within a few days to weeks after recovery. Can be long-lasting or permanent; linked to ongoing health issues.
Associated Symptoms Usually include fever, congestion, cough, or sore throat. May include fatigue, unexplained weight loss, or pain.
Treatment Focus Addressing the infection with rest, hydration, and over-the-counter remedies. Treating the underlying medical condition; symptom management.
Recovery Senses of taste and smell typically return to normal. Recovery depends on the underlying condition and its treatment.

Conclusion

Loss of appetite and taste are symptoms, not diseases, and can have a wide array of underlying causes, from minor viral infections to more complex chronic conditions. While a simple cold may temporarily dull your senses, persistent or sudden changes warrant a consultation with a healthcare provider to rule out more serious issues. By identifying and treating the root cause, whether it's a medication side effect, a nutritional deficiency, or an underlying illness, you can work towards restoring your enjoyment of food and maintaining good health.

For more information on the link between taste and general health, you can visit the Johns Hopkins Medicine website.

Frequently Asked Questions

Yes, persistent or sudden loss of appetite and taste can be a symptom of a serious illness, including certain types of cancer, neurological conditions like Parkinson's, or chronic diseases such as kidney or liver failure. It's important to consult a doctor if the symptoms last longer than a couple of weeks.

For most common viral illnesses like the cold or flu, your sense of taste and appetite should return to normal within a few days to a week after recovering. If symptoms persist, other factors may be at play.

A wide range of medications can affect your sense of taste, including many antibiotics (like metronidazole), blood pressure drugs (like captopril), certain antidepressants, and chemotherapy agents.

Yes, quitting smoking can have a positive impact on your senses. Smoking can damage taste buds, and many people report an improvement in their sense of taste within 48 hours of quitting.

Deficiencies in key nutrients, particularly zinc and Vitamin B12, have been associated with a loss or alteration of taste. Proper nutrition is essential for maintaining healthy taste function.

A gradual decrease in taste sensitivity can occur with aging due to a natural decline in the number of taste buds. However, a significant or sudden change should not be assumed to be normal and should be evaluated by a healthcare provider.

Medically, anorexia is the term for a loss of appetite, which is an involuntary symptom. The term is often confused with the eating disorder 'anorexia nervosa,' which is a psychological condition involving the intentional restriction of food intake.

References

  1. 1
  2. 2
  3. 3

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.