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What drinks should I avoid mixing? A nutritional guide

4 min read

According to the Centers for Disease Control and Prevention (CDC), mixing alcohol and caffeine can mask the depressant effects of alcohol, leading people to drink more and engage in riskier behaviors. If you’ve ever wondered, “What drinks should I avoid mixing?” this guide provides essential nutritional and safety information to help you make informed choices.

Quick Summary

Several common beverage combinations can lead to negative health consequences, including heightened intoxication, dangerous side effects with medication, and digestive issues. Understanding the risks of pairing alcohol with energy drinks, diet sodas, and certain medicines is key to maintaining personal health and safety. The order and type of alcohol mixed can also affect your body's reaction and next-day hangover severity.

Key Points

  • Avoid Alcohol and Caffeine: The stimulant in energy drinks masks alcohol's sedative effects, leading to overconsumption, risky behavior, and heart strain.

  • Never Mix Medication with Alcohol: Combining alcohol with medications like NSAIDs, antidepressants, and opioids can cause severe side effects, internal bleeding, and overdose.

  • Be Aware of Diet Soda and Alcohol: Mixing alcohol with diet drinks can lead to a faster increase in blood alcohol concentration, causing quicker intoxication.

  • Be Cautious with Dairy and Acidic Juices: Combining milk with citrus juice can cause curdling in the stomach, leading to indigestion and bloating for sensitive individuals.

  • Understand the Role of Congeners: Mixing different types of alcohol, particularly darker spirits, increases the intake of congeners, which can lead to more severe hangovers.

  • Prioritize Hydration: Both alcohol and caffeine are diuretics; drinking water in between mixed drinks can help prevent dehydration and associated symptoms like headaches.

  • Monitor Sugary Mixers: High-sugar mixers in cocktails add empty calories and can mask the alcohol taste, leading to overconsumption and potential weight gain.

In This Article

The Dangerous Duo: Alcohol and Energy Drinks

One of the most widely recognized risky beverage combinations is mixing alcohol with energy drinks. While this mixture is common, especially among younger crowds, it carries significant health hazards. Caffeine, a potent stimulant, can mask the sedative effects of alcohol, which is a depressant. This counteractive effect can lead a person to feel less intoxicated and more alert than they truly are, which often results in drinking more alcohol than intended.

Why the combination is dangerous

  • Increased Binge Drinking: Feeling less drunk can lead to overconsumption and higher rates of binge drinking, which significantly increases the risk of alcohol poisoning.
  • Higher Risk of Injury: Impaired judgment combined with a false sense of alertness increases the likelihood of risky behaviors, such as drunk driving, fights, and accidents.
  • Cardiovascular Strain: Both caffeine and alcohol are diuretics and can lead to dehydration. Combining them places extra strain on the heart, potentially causing an irregular heartbeat (arrhythmia) and elevated blood pressure.

Unsafe Pairings: Alcohol and Medications

Mixing alcohol with medications, whether prescription or over-the-counter, can produce dangerous and sometimes life-threatening results. The liver is responsible for metabolizing both alcohol and many medications. When both are present, the liver’s ability to process them is impaired, which can increase the potency of the drug or make it less effective.

Common medication interactions

  • Painkillers (NSAIDs): Mixing alcohol with NSAIDs like ibuprofen can increase the risk of stomach bleeding and ulcers.
  • Antidepressants: Alcohol can worsen the side effects of antidepressants, including drowsiness, dizziness, and impaired concentration. It can also exacerbate feelings of depression and anxiety.
  • Antibiotics: Certain antibiotics, such as metronidazole, can cause unpleasant side effects like nausea, headaches, and palpitations when combined with alcohol. It is often recommended to wait several days after finishing a course before drinking again.
  • Opioid Painkillers: The combination of opioids and alcohol can dangerously slow breathing and heart rate, increasing the risk of overdose, coma, and death.

Surprising Combinations to Avoid for Digestive Health

Some beverage pairings can cause digestive discomfort and nutritional interference, even if they aren't immediately life-threatening. Certain acidic and dairy combinations, in particular, can be challenging for the stomach.

Milk and citrus juice

According to Ayurveda and some nutritionists, mixing milk with acidic juices like orange or lemon can cause the milk to curdle in the stomach, leading to indigestion, bloating, and potential acid reflux. This happens because the acid coagulates the milk's proteins. For those with sensitive digestive systems, it's best to allow a significant time gap between consuming these two types of beverages.

Mixing different types of alcohol

Contrary to popular myth, mixing different types of alcohol (e.g., wine and beer) doesn't inherently make you sicker than drinking the same quantity of a single type. However, the real danger lies in increased alcohol consumption and the presence of congeners—chemical byproducts of fermentation that contribute to hangovers. Darker liquors like whiskey and red wine have more congeners than lighter liquors like vodka. Mixing different types can lead to a higher intake of these chemicals, resulting in a more severe hangover.

The Effect of Sugary Mixers and Diet Soda

Adding high-sugar mixers to alcoholic drinks, such as regular soda or fruit juices, can be detrimental to your health. The high calorie and sugar content can lead to weight gain and increase the risk of type 2 diabetes. Additionally, the sweetness can mask the alcohol's taste, causing you to drink more without realizing it.

Conversely, research shows that mixing alcohol with diet soda can lead to a quicker increase in blood alcohol concentration (BAC) compared to sugary mixers. This is because the body does not slow down absorption to process the sugar, causing the alcohol to enter the bloodstream more rapidly. This can make you feel intoxicated faster and impair your judgment sooner.

Comparison of Mixed Drink Risks

Combination Main Risk(s) Key Mechanism Best Avoided By
Alcohol + Energy Drink Increased binge drinking, cardiovascular strain, alcohol poisoning Stimulant masks alcohol's depressant effect; increases heart rate and blood pressure Young adults, binge drinkers, those with heart conditions
Alcohol + NSAIDs (Painkillers) Stomach bleeding, ulcers Alcohol and NSAIDs irritate the stomach lining Anyone, especially those with pre-existing digestive issues
Alcohol + Antidepressants Worsened side effects (drowsiness), ineffective medication Amplified sedative effects, potential for increased depression Individuals with mental health conditions on medication
Milk + Citrus Juice Indigestion, bloating, curdling Acid in juice coagulates milk proteins Individuals with sensitive stomachs or dairy intolerance
Mixing Types of Alcohol (Especially darks) More severe hangovers Higher intake of congeners, which are chemical byproducts Individuals prone to severe hangovers
Alcohol + Diet Soda Faster intoxication, impaired judgment Absence of sugar accelerates alcohol absorption Social drinkers trying to moderate intake

How to Drink Safely

  • Always check medication labels. If the label warns against consuming alcohol, take that advice seriously. If unsure, consult your doctor or pharmacist.
  • Stick to one type of alcoholic beverage for the night, especially if you're sensitive to congeners.
  • Avoid energy drinks as mixers with alcohol. Instead, use non-caffeinated and low-sugar alternatives like club soda or a splash of natural juice.
  • Stay hydrated by alternating alcoholic drinks with water to combat dehydration caused by both alcohol and caffeine.
  • Know your limits and pace yourself, regardless of the drink combination.

Conclusion

Understanding what drinks should I avoid mixing is a cornerstone of responsible and safe consumption. From the potentially dangerous masking effects of mixing alcohol with stimulants like caffeine, to the digestive turmoil caused by combining acidic juices with dairy, these dietary interactions have real consequences. By paying attention to these key combinations—and especially by heeding warnings about medication—you can protect your health, avoid uncomfortable side effects, and make smarter choices about what you drink.

Frequently Asked Questions

Mixing alcohol with diet soda can actually be less safe than using a sugary mixer. The absence of sugar allows alcohol to be absorbed into the bloodstream faster, leading to a more rapid increase in blood alcohol concentration (BAC) and quicker intoxication.

Energy drinks contain stimulants like caffeine, which can mask the depressant effects of alcohol. This makes you feel more alert even while intoxicated, often causing you to drink more than you can handle, increasing the risk of binge drinking, accidents, and heart strain.

While mixing different alcohols doesn't directly worsen intoxication, it can lead to a more severe hangover due to increased intake of congeners, which are chemical byproducts found in higher concentrations in darker liquors. The main issue is often the quantity consumed when mixing, rather than the act of mixing itself.

Mixing alcohol with medication is extremely dangerous and can cause severe health problems, including increased side effects, internal bleeding, and liver damage. It's crucial to check with a doctor or pharmacist about any medication you are taking, as even over-the-counter drugs can interact harmfully with alcohol.

The high acidity of citrus juice can cause the milk's proteins to coagulate, or curdle, inside your stomach. For many people, especially those with sensitive digestive systems, this can lead to indigestion, bloating, and upset stomach.

No, adding sugar to alcohol after fermentation does not increase its alcoholic strength (ABV). In fact, the sugar can sometimes slow down the absorption of alcohol into the bloodstream. However, sugary drinks often mask the taste of alcohol, which can lead to consuming more than you realize.

To drink safely, avoid mixing alcohol with medications or energy drinks, stick to one type of alcohol if prone to hangovers, and be mindful of sugary mixers. Always check medication labels and stay hydrated by drinking water throughout the night. It is most important to know and respect your own limits.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.