What is Jubilance?
Jubilance is a nutritional supplement created by Terra Biological LLC specifically for women experiencing emotional symptoms of Premenstrual Syndrome (PMS). It is not a drug, but a vegan, hormone-free, and non-GMO product intended to provide relief from mood-related issues such as anxiety, stress, irritability, and sadness before and during a menstrual cycle.
The primary active ingredient in Jubilance is a patented compound called Thermally Stabilized Oxaloacetate (OAA). This ingredient is paired with Vitamin C to ensure maximum bioavailability, or the efficient absorption and utilization of the compound by the body. The supplement is designed to be taken once daily throughout the entire month for proactive and consistent support.
How Oxaloacetate Works to Alleviate PMS
The science behind Jubilance centers on the role of OAA in brain energy and glucose regulation. During PMS, some women experience hormonal fluctuations that cause the brain, particularly the cerebellum, to demand more sugar for energy. This erratic energy demand can lead to emotional volatility and classic PMS mood symptoms like irritability or sadness.
Oxaloacetate is a key metabolite involved in cellular energy production (the Krebs cycle) and gluconeogenesis, the process of creating new glucose. By supplementing with thermally stabilized OAA, Jubilance helps the liver maintain a steady supply of glucose to the brain. This steady energy supply helps prevent the drastic "sugar crash" that often follows carbohydrate cravings, smoothing out mood swings.
Furthermore, OAA has been shown in animal studies to affect the balance of two key brain chemicals: glutamate and GABA. An imbalance in this ratio can exacerbate emotional conditions. OAA works to balance these chemicals by lowering excess glutamate levels and increasing GABA, which helps calm the brain and regulate mood.
Scientific Backing and Claims
Jubilance is backed by gold-standard, peer-reviewed clinical trials demonstrating its effectiveness in reducing PMS-related mood symptoms. The studies showed significant improvements in anxiety, gloominess, stress, and irritability after just one month of daily use. As a result of this research, the U.S. Food and Drug Administration (FDA) has recognized a Structure/Function claim for oxaloacetate in Jubilance: "Oxaloacetate may help alleviate the mild to moderate psychological and/or behavioral symptoms associated with Premenstrual Syndrome (PMS)".
It is important to note that while the clinical trials showed strong results, individual responses can vary. Some users report life-changing relief, while others find the effects less pronounced or experience mild side effects, such as bloating. The product is intended for those with mild to moderate symptoms and is not a treatment for more severe conditions like Premenstrual Dysphoric Disorder (PMDD).
Is Jubilance the Right Choice for You?
Choosing a PMS supplement depends on your specific needs, and Jubilance offers a distinct, non-hormonal approach. Here is a comparison to highlight its unique position in the market:
| Feature | Jubilance (Oxaloacetate) | Traditional Herbal Remedies (e.g., Chasteberry) | OTC Pain Relievers (e.g., Ibuprofen) |
|---|---|---|---|
| Mechanism | Targets brain glucose and neurotransmitter balance. | Often works by influencing hormonal pathways. | Addresses physical symptoms by reducing prostaglandins. |
| Primary Target | Emotional and psychological symptoms (mood swings, anxiety). | Can address both physical and emotional symptoms, but efficacy varies. | Physical symptoms (cramps, headaches). |
| Clinical Evidence | Backed by multiple double-blind, peer-reviewed clinical trials. | Research and clinical support is less consistent and often less rigorous. | Widely proven for pain relief. |
| Ingredients | Thermally Stabilized Oxaloacetate and Vitamin C; vegan, non-GMO. | Varies widely; herbs, vitamins, minerals. | Active ingredients like ibuprofen or naproxen sodium. |
| Daily Dosage | One capsule daily, all month long. | Varies; may be taken only during symptomatic days. | Taken on an as-needed basis for pain. |
| Side Effects | Few reported; mild side effects like digestive upset are possible. | Varies depending on ingredients; potential hormonal effects. | Potential for digestive issues, especially with prolonged use. |
It is clear that Jubilance, with its focus on the underlying neurological mechanisms rather than hormone manipulation, presents a novel option for those whose main PMS struggles are emotional. Its clinical backing adds a layer of reassurance often missing from other supplements.
Conclusion
Jubilance is a clinically proven, non-hormonal nutritional supplement formulated to combat the emotional and psychological symptoms of PMS. By using a patented form of oxaloacetate, it targets the root cause of mood swings, stress, anxiety, and gloominess by stabilizing brain glucose levels and balancing key neurotransmitters. Unlike traditional hormonal therapies, it offers a different approach for women seeking a more balanced emotional state throughout their menstrual cycle. While individual results can differ, its foundation in scientific research provides a compelling case for its consideration as an effective and safe option for managing mild to moderate PMS mood symptoms. For more detailed information on the clinical studies, you can refer to the National Institutes of Health research on oxaloacetate supplementation for PMS, archived on their website.
