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What is BV in nutrition? Exploring protein quality and Biological Value

4 min read

Protein quality can vary drastically, with some sources being far more efficient for the human body than others. This difference is measured by various methods, including the Biological Value (BV) score, which helps explain what is BV in nutrition by quantifying a protein's utility for growth and maintenance.

Quick Summary

BV, or Biological Value, measures the proportion of absorbed protein from a food that is retained and used by the body. A higher BV indicates a more efficiently utilized protein source, determined primarily by its amino acid composition and balance.

Key Points

  • Definition: Biological Value (BV) measures the proportion of absorbed protein that is used by the body for protein synthesis.

  • Amino Acid Balance: BV is heavily influenced by the essential amino acid (EAA) content and balance of a protein source.

  • Measurement: BV is calculated using nitrogen balance studies, comparing nitrogen absorbed versus nitrogen retained.

  • Animal vs. Plant Proteins: Animal proteins generally have a higher BV due to a more complete amino acid profile, but plant proteins can be combined to achieve a high-quality mix.

  • Modern Context: While foundational, BV has been largely replaced by more accurate human-centric metrics like PDCAAS and DIAAS, which account for digestibility and do not cap scores.

  • Dietary Strategy: To maximize protein quality, consume a diverse diet, and combine different protein sources to ensure a complete intake of essential amino acids.

In This Article

What is BV in nutrition?

Biological Value, or BV, is a system for rating the quality of a protein source based on how efficiently the human body can utilize it. It specifically measures the ratio of nitrogen absorbed by the body to the nitrogen retained, with the remainder being used for protein synthesis. A protein with a high BV score, such as whole egg, has an amino acid profile that closely matches the body's needs, allowing for maximum retention and use for building and repairing tissues. Conversely, a protein with a lower BV has a less ideal amino acid composition, resulting in less efficient utilization.

The role of amino acids

To understand BV, one must first grasp the concept of amino acids. Proteins are long chains of amino acids, and there are 20 different types used by the human body. Nine of these are considered 'essential' because the body cannot produce them on its own and must obtain them from the diet. The quality of a protein is largely determined by its essential amino acid (EAA) profile. If a protein source is missing or low in just one EAA, it can become a 'limiting amino acid,' restricting the body's ability to synthesize new proteins. A high BV protein supplies all EAAs in the proper proportions, ensuring that no bottleneck in protein synthesis occurs.

How is Biological Value measured?

The traditional method for determining BV involves a controlled study known as a nitrogen balance test.

  • Methodology: A test subject consumes a diet with only the protein being measured. Researchers carefully measure the nitrogen intake (from the food) and compare it to the nitrogen excreted (in urine and feces).
  • Calculation: The formula is relatively straightforward: $BV = \frac{\text{Nitrogen Retained}}{\text{Nitrogen Absorbed}} \times 100$. Nitrogen retained is calculated by subtracting excreted nitrogen from absorbed nitrogen.
  • Standardization: For comparison, a highly absorbable protein, typically egg, is often used as a benchmark with a relative BV of 100, although its true percentage BV is closer to 93.7%.

Factors affecting Biological Value

Several factors can influence a protein's BV, highlighting the complexity of protein metabolism beyond just amino acid content.

  • Food Preparation: Cooking, heating, and processing can affect the bioavailability of amino acids within a protein. For example, a raw soybean has lower protein bioavailability than a prepared soy protein isolate.
  • Dietary Context: The BV of a protein is not an absolute constant. When proteins are combined in a meal (e.g., rice and beans), they can complement each other, improving the overall amino acid balance and raising the effective BV.
  • Individual Metabolism: A person's metabolic rate, health status, and age can all impact how efficiently they use protein. For example, individuals with higher protein needs, such as growing children, have different requirements than adults.

High and low BV food examples

To give a practical understanding, here is a list of common foods and their typical BV scores. Note that BV values can vary based on specific preparation methods and reference scales.

  • High BV Foods:
    • Whey Protein Isolate: Often has a relative BV exceeding 100 due to its efficient absorption and amino acid profile.
    • Whole Egg: Considered the gold standard, with a high BV score.
    • Milk Protein (Casein and Whey): High-quality, complete protein with a high BV.
    • Fish and Meat: Generally high in BV, though slightly lower than eggs.
  • Medium BV Foods:
    • Soy Protein: A complete plant-based protein with a relatively high BV.
    • Quinoa: Another complete plant-based protein, with a decent BV score.
  • Low BV Foods:
    • Wheat Flour: Low in lysine, which makes it an 'incomplete' protein with a lower BV.
    • Gelatin: Lacks several essential amino acids, giving it a very low BV.

Comparing BV with newer protein scoring methods

Over time, limitations in the BV scoring method have led to the development of more advanced and comprehensive protein quality assessments. The FDA and WHO now recommend more modern methods that better reflect human needs.

Feature Biological Value (BV) Protein Digestibility Corrected Amino Acid Score (PDCAAS) Digestible Indispensable Amino Acid Score (DIAAS)
Focus Percentage of absorbed nitrogen retained. Corrected for human amino acid requirements and fecal digestibility. Corrected for human amino acid requirements and ileal digestibility.
Digestibility Does not account for digestibility. Accounts for fecal digestibility. Measures digestibility at the ileum, which is more accurate.
Reference Needs Based on animal studies; application to humans is limited. Based on human needs, typically a 2-5 year old child. More accurate human reference values.
Scoring Range Can go up to 100% or higher (relative). Capped at 1.0, limiting the comparison of high-quality proteins. Not capped at 100%, allowing for more precise differentiation.
Consideration An older and less relevant method for modern human nutrition. More relevant but still has limitations, such as score truncation. Considered the most accurate and advanced method today.

Conclusion

Understanding what is BV in nutrition provides a foundational perspective on protein quality, emphasizing the importance of a protein's amino acid profile for efficient bodily utilization. While the metric has limitations and has been largely superseded by more accurate methods like PDCAAS and DIAAS, the core principle remains valid. For a nutritionally sound diet, consuming a variety of protein sources, both animal and plant-based, ensures a complete and balanced intake of essential amino acids. By focusing on whole foods and smart food pairings, you can maximize your protein's effectiveness for muscle repair, growth, and overall health. For further reading, consult resources like the Food and Agriculture Organization (FAO) for protein quality evaluation guidelines.

Frequently Asked Questions

A protein source with a high Biological Value (BV) is one that has a balanced profile of all nine essential amino acids, allowing the body to efficiently use the absorbed protein. Animal-based proteins like whole eggs, whey, and milk are typically considered high BV sources.

A protein is considered 'incomplete' or to have a low BV if it is deficient in one or more of the nine essential amino acids that the body cannot produce itself. For example, wheat protein is low in the amino acid lysine.

No, BV only considers the protein that has been absorbed by the body. It does not account for the portion of protein that is not digested and is excreted as waste.

While it provides a foundational concept, BV is not the primary metric used today. More advanced and accurate scoring systems like PDCAAS and DIAAS have largely replaced it because they better reflect human protein needs and digestion.

By combining different plant-based protein sources, like pairing legumes with grains (e.g., rice and beans), you can achieve a complete amino acid profile similar to high-BV animal proteins. This is known as protein complementation.

The main difference is that PDCAAS (Protein Digestibility-Corrected Amino Acid Score) accounts for digestibility in humans and is based on human amino acid requirements, whereas BV focuses only on absorbed protein and was historically based on animal studies.

Yes, food preparation methods like cooking and heating can damage or alter amino acids, potentially affecting their availability and, consequently, the protein's overall Biological Value.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.