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What is Harmful About Red Dye?

4 min read

According to the FDA, red dye 3 was banned for use in foods and ingested drugs starting in January 2025 due to evidence linking it to cancer in animals. The question of what is harmful about red dye, however, extends beyond just one colorant, encompassing other dyes like red dye 40 and a range of health concerns.

Quick Summary

Several artificial red food colorings, derived from petroleum, have been linked to health concerns like hyperactivity in children, allergic reactions, and inflammation. Regulatory agencies have banned or restricted specific red dyes based on animal studies and accumulating evidence regarding their safety.

Key Points

  • Red Dye 3 Ban: The FDA announced a nationwide ban on red dye 3 for use in foods and ingested drugs, effective January 2025, due to evidence linking it to cancer in animal studies.

  • Red Dye 40 Concerns: Red dye 40 is linked to neurobehavioral issues, including hyperactivity and ADHD symptoms in sensitive children, as well as allergic reactions and gut inflammation.

  • Petroleum Derived: Both red dye 3 and red dye 40 are synthetic colorants derived from petroleum, with no nutritional value.

  • Contaminants: Red dye 40 contains trace amounts of carcinogenic contaminants like benzidine, raising long-term health concerns.

  • Global Discrepancy: Regulatory standards differ globally; Europe requires warning labels for red dye 40, while the U.S. is just now phasing out artificial dyes.

  • Avoidance Strategy: To avoid artificial red dyes, read ingredient labels carefully for specific dye names, choose products with natural colorants, and prioritize whole, unprocessed foods.

In This Article

Concerns Surrounding Red Dye 40

Red dye 40, also known as Allura Red AC, is a common artificial food coloring derived from petroleum. It has been linked to potential health risks, particularly in children.

Neurobehavioral Effects in Children

Studies suggest a link between artificial food dyes, including red dye 40, and adverse neurobehavioral effects in some children, such as increased hyperactivity and inattentiveness. Not all children are affected, but some may be particularly sensitive.

Allergic and Inflammatory Reactions

Red dye 40 may cause allergic reactions like hives or migraines in some individuals. Research in mice also suggests continuous exposure could lead to gut inflammation and alter the gut microbiome, raising questions about its long-term impact on human digestive health.

Carcinogenic Contaminants

The dye is known to contain trace amounts of cancer-causing substances like benzidine from the manufacturing process. While levels are low, long-term exposure is a concern.

The National Ban on Red Dye 3

FD&C Red No. 3 (Erythrosine) has been used in foods despite evidence of potential harm. Animal studies in the 1980s linked high doses to thyroid tumors in male rats. The FDA banned its use in cosmetics in 1990 but delayed action on food for decades. Following a California ban in 2023, the FDA announced a nationwide ban on red dye 3 in foods and ingested drugs, effective January 2025.

Understanding the Difference Between Red Dyes

Red dye 3 and red dye 40 have different primary concerns and regulatory statuses. Red dye 3 was banned due to its link to cancer in animal studies. Red dye 40 is primarily scrutinized for potential neurobehavioral and inflammatory effects and is not currently banned in the U.S., although a phase-out is planned. For a detailed comparison of red dye 40 and red dye 3, including source, status, concerns, and use, please see {Link: Drugs.com https://www.drugs.com/medical-answers/red-dye-40-bad-you-3579805/}.

Avoiding Artificial Red Dyes

Many choose to avoid artificial red dyes, especially for sensitive individuals, including children. To avoid artificial red dyes, steps include carefully reading ingredient labels for specific dye names, choosing natural alternatives, prioritizing whole foods, and cooking at home more often.

Conclusion: Navigating the Controversy

The science on artificial red dyes highlights proven risks and ongoing research. While red dye 3 is banned, concerns remain about red dye 40 and its effects. Consumers should be informed about potential health implications, especially for children. Reading labels and choosing whole, naturally-colored foods can help reduce exposure.

For additional information on food additives and children's health, consult reliable sources like the American Academy of Pediatrics.

Disclaimer: The information provided is for educational purposes only and is not a substitute for professional medical advice. Always consult a healthcare provider for any health concerns.

Natural Coloring Options

Natural alternatives for vibrant colors include beet juice (red), strawberry puree (pink), berry extracts (purple/blue), and turmeric or paprika (orange/yellow). Carmine is another red option derived from insects.

What to Look For on Labels

Look for "FD&C Red No. 40," "FD&C Red No. 3," "Red 40," Allura Red AC (E129), or Erythrosine (E127). Natural colorants are often listed by their source, like "colored with beet juice."

The Ultra-Processed Food Connection

Artificial dyes are often in ultra-processed foods, which lack nutritional value. Avoiding these dyes often means avoiding foods high in added sugars, unhealthy fats, and sodium.

Future of Artificial Dyes

The regulatory landscape is changing, with the FDA banning red dye 3 and planning to phase out other artificial color additives by late 2026. This is pushing the food industry towards natural colorants.

Long-Term Health Impact

Beyond short-term effects, concerns exist about the long-term impact of synthetic food dyes. Research suggests potential DNA damage and inflammation. The full extent of these effects over a lifetime needs more study.

Regulatory Differences

Regulatory approaches differ globally. The EU requires warning labels for red dye 40, a more cautious approach than the historical U.S. stance. However, recent FDA actions show a shift towards aligning with global standards.

Making a Healthier Choice

Concerns about red dye and other artificial colorants are growing due to links to behavioral issues, allergies, inflammation, and potential long-term risks. The ban on red dye 3 and the planned phase-out of other dyes indicate a move towards safer practices. Choosing whole foods and reading labels are key steps.

Final Thoughts on Food Dyes

Artificial food colorings offer no nutritional benefit. Evidence of potential health risks strengthens the case for reducing reliance on these additives. Embracing the natural colors of food and choosing dye-free options supports a healthier diet overall.

Avoiding Dyes in Medications

Artificial colorants are also in many medications. Look for “dye-free” versions or check the inactive ingredients list. A pharmacist can help find dye-free options.

List of Products That Historically Contained Red Dye 3

  • Maraschino Cherries
  • Some Canned Fruit Cocktails
  • Certain Candies, like Conversation Hearts and Candy Corn
  • Chewable Vitamin Tablets
  • Select Cough Syrups and Liquid Medications
  • Certain Strawberry-flavored Drinks and Gelatins

What to Know About Red Dye 40 and ADHD

For parents concerned about ADHD, studies link red dye 40 to increased hyperactivity in sensitive children. Identifying sensitivities may involve a food diary and discussion with a healthcare provider.

Outbound Link

For a detailed scientific review on the toxicology of various food dyes, you can refer to this {Link: PubMed article https://pubmed.ncbi.nlm.nih.gov/23026007/}.

Frequently Asked Questions

The primary health risk associated with red dye 3 is its link to cancer. Animal studies in the 1980s showed it caused thyroid tumors in rats, leading to the FDA banning its use in cosmetics in 1990 and eventually in foods and ingested drugs in 2025.

Research has linked red dye 40 to increased hyperactivity and other neurobehavioral issues in some children, particularly those with ADHD. Some children appear sensitive, and removing the dye can sometimes improve symptoms.

No, red dye 40 is not currently banned in the U.S. However, in April 2025, the FDA announced plans to phase out all remaining artificial color additives, including red dye 40, by the end of 2026.

To avoid red dyes, carefully read ingredient labels for terms like "FD&C Red No. 40" or "Allura Red AC". Opt for products colored with natural alternatives like beet juice or paprika extract, and focus on consuming whole, unprocessed foods.

The key differences are their primary health risks and regulatory status. Red dye 3 was banned due to its link to cancer in animal studies, while red dye 40 is primarily associated with behavioral and inflammatory issues. Red dye 3 is banned in the U.S., but red dye 40 is currently still in use.

Yes, many natural alternatives are available, including beet juice, anthocyanins from berries like pomegranate or raspberry, and carmine, a red dye derived from cochineal insects.

Despite knowing since the 1980s that red dye 3 was a carcinogen in animals, the FDA did not act to ban it from food at the same time it banned it from cosmetics in 1990. It took over 30 years and a petition from consumer advocacy groups for the FDA to finally enforce the ban in 2025.

A 2012 review found that all nine FDA-approved dyes raised some level of health concern, including issues like cancer risk, allergic reactions, and genotoxicity. However, the severity and type of risk vary among different dyes.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.