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What is monolaurin found in? Exploring natural and supplemental sources

4 min read

A study published in the journal Nature in 2019 demonstrated that human milk contained significantly higher concentrations of glycerol monolaurate (GML), or monolaurin, than cow's milk. So, what is monolaurin found in, and what makes this natural compound a subject of interest in both nutrition and medicine? This fascinating molecule originates from a common dietary fatty acid and is available from several sources for those seeking its beneficial properties.

Quick Summary

Monolaurin is a chemical made from lauric acid, found abundantly in coconut oil, palm kernel oil, and human breast milk. It is also available as a dietary supplement for concentrated intake.

Key Points

  • Coconut Oil: The richest natural food source, containing high levels of lauric acid which the body converts into monolaurin.

  • Human Breast Milk: A significant natural source of monolaurin, providing antimicrobial protection to infants.

  • Supplements: Monolaurin is available in a concentrated capsule or pellet form derived from coconut oil for direct intake.

  • Antimicrobial Action: Monolaurin works by dissolving the fatty lipid membrane of many pathogens, including enveloped viruses, certain bacteria, and fungi.

  • Lauric Acid Precursor: The body produces monolaurin from the lauric acid consumed in foods like coconut oil, although supplementation offers a more direct route.

In This Article

The Primary Natural Sources of Monolaurin

Monolaurin is technically a monoglyceride, a compound formed from glycerol and lauric acid. While it exists naturally in some places, it is most often created in the body when digestive enzymes break down lauric acid from dietary fats. Therefore, the most important sources to consider are those rich in lauric acid.

Coconut Oil and Coconut Products

Coconut oil is, without a doubt, the single richest natural source of lauric acid. It is comprised of approximately 50% lauric acid, a 12-carbon medium-chain fatty acid. When consumed, the body processes this lauric acid and converts it into monolaurin, unlocking its powerful antimicrobial potential. Other coconut products also contain lauric acid, but in lesser quantities compared to the oil.

  • Coconut Oil: The most concentrated dietary source.
  • Fresh Coconut: Contains a significant amount of lauric acid in its meat.
  • Coconut Milk & Cream: Provides lauric acid, though in a more diluted form.

Human Breast Milk

One of the most notable natural occurrences of monolaurin is in human breast milk, where it plays a crucial role in supporting an infant's developing immune system. Studies have shown that the concentration of GML in human milk is significantly higher than in bovine milk. This highlights the compound's importance in providing natural, broad-spectrum protection against a variety of pathogens during a critical stage of development.

Other Sources

While less concentrated, lauric acid and its derivatives are also found in other foods and ingredients:

  • Palm Kernel Oil: Similar to coconut oil, palm kernel oil is another vegetable-based source of lauric acid.
  • Cow and Goat Milk: These milks contain small percentages of lauric acid, though in much lower concentrations than human breast milk.
  • Some Supplements: Saw Palmetto and Bitter Melon have also been mentioned as containing monolaurin, though sourcing is often from coconut oil.

Monolaurin Supplements and Formulations

For those seeking a targeted and concentrated intake, monolaurin is widely available in supplement form. Supplements offer a way to bypass the body's conversion process and deliver a consistent, therapeutic dose directly. These supplements are typically sold in capsule or pellet form and are derived from coconut oil. The United States Food and Drug Administration (FDA) has classified monolaurin as Generally Recognized as Safe (GRAS) for use in foods.

How Monolaurin Works as an Antimicrobial

Research has explored monolaurin's potent antimicrobial properties, observing its effects in test tubes and animal studies. Its mechanism of action is particularly effective against certain microbes:

  • Disruption of Viral Envelopes: Monolaurin attacks the lipid-protein envelope that surrounds many viruses, including herpes and influenza. By dissolving this protective layer, it prevents the virus from attaching to and entering host cells, effectively halting infection.
  • Antibacterial Action: It has been shown to be effective against certain bacteria, particularly Gram-positive types like Staphylococcus aureus (Staph), by disrupting their cell membranes.
  • Antifungal Activity: Monolaurin also acts as an antifungal agent, with studies showing its effectiveness against biofilms produced by Candida albicans, a common fungal pathogen.

Monolaurin vs. Lauric Acid: A Comparison

Understanding the distinction between monolaurin and lauric acid is key to appreciating their roles. While one is the precursor, the other is the active component responsible for most of the antimicrobial benefits.

Feature Monolaurin Lauric Acid
Chemical Type A monoglyceride (glycerol + 1 lauric acid) A medium-chain saturated fatty acid
Source Found in human breast milk; formed in the body from lauric acid Found naturally in high concentration in coconut oil and palm kernel oil
Primary Function Acts directly as a potent antimicrobial agent A precursor that is converted by the body into monolaurin
Absorption/Availability Delivered directly in supplement form for higher concentration Must be converted enzymatically within the body, with uncertain conversion rates
Therapeutic Efficacy Considered to be significantly more potent than lauric acid in its antimicrobial effects Less effective than monolaurin as a direct antimicrobial agent

Conclusion: A Natural Immune Aid

In summary, monolaurin is a naturally occurring monoglyceride that is primarily found in human breast milk and is created in the body from the lauric acid abundant in coconut and palm kernel oils. It is also widely available in supplemental form for those wishing to increase their intake directly. Its notable ability to disrupt the protective lipid layer of certain viruses and bacteria has led to growing interest in its use for immune support and overall wellness. While more human clinical research is needed, particularly regarding oral supplementation, the established antimicrobial actions and a history of safe use as a food additive make monolaurin a compelling natural ingredient. For centuries, coconut oil has been used in traditional medicine, but only recently has science pinpointed monolaurin as a key active compound.

One authoritative source on this topic is the National Institutes of Health, which hosts a number of relevant peer-reviewed studies, such as the review on clinical applications of monolaurin: The Clinical Use of Monolaurin as a Dietary Supplement.

Frequently Asked Questions

The primary natural food source is coconut oil, which is exceptionally high in lauric acid. The body's digestive enzymes then convert this lauric acid into monolaurin.

Yes, human breast milk contains a significant amount of monolaurin, which is thought to provide natural antimicrobial and immune support to infants.

Monolaurin supplements provide a concentrated dose of the active compound, bypassing the body's conversion process from lauric acid. This can be more effective for those seeking targeted therapeutic levels, as the body's conversion rate from coconut oil is unknown.

Lauric acid is the raw material found in foods like coconut oil. Monolaurin is the more potent, active monoglyceride that is produced when the body digests lauric acid.

Monolaurin is classified by the FDA as Generally Recognized as Safe (GRAS) for use in foods. It is generally well-tolerated, but it's always best to consult a healthcare provider before beginning any new supplement regimen.

Yes, other sources of lauric acid include palm kernel oil and small amounts in dairy from cows and goats.

Monolaurin supports the immune system primarily through its antimicrobial properties. It works by disrupting the protective lipid membranes of certain viruses and bacteria, preventing them from replicating and causing infection.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.