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What is the best drink for nitric oxide? A guide to boosting your intake.

4 min read

Studies show that supplementing with dietary nitrates, primarily from beetroot juice, can increase nitric oxide levels in the body by over 20% in as little as 45 minutes. This makes beetroot a strong contender when asking what is the best drink for nitric oxide, though other powerful options also exist to support cardiovascular health and athletic performance.

Quick Summary

This guide explores several drinks, including beetroot, pomegranate, and watermelon juice, known to naturally boost nitric oxide levels by providing nitrates, citrulline, or powerful antioxidants to support vascular health and exercise capacity.

Key Points

  • Beetroot is a top contender: Due to its high concentration of dietary nitrates, beetroot juice is highly effective for a rapid increase in nitric oxide production.

  • Watermelon provides citrulline: This amino acid is converted to arginine, a precursor for NO, offering a slower but sustained boost in nitric oxide levels.

  • Pomegranate protects nitric oxide: Rich in antioxidants, pomegranate juice helps preserve existing nitric oxide from oxidative damage, enhancing its biological actions.

  • Leafy green smoothies are a comprehensive option: Blending nitrate-rich greens like spinach and kale with vitamin C from citrus offers multiple pathways to support NO levels.

  • Timing can matter for goals: For an immediate boost before exercise, opt for high-nitrate beetroot juice. For general health, incorporating varied sources throughout the day is beneficial.

In This Article

The Science Behind Nitric Oxide

Nitric oxide (NO) is a crucial signaling molecule produced naturally in the body. It plays a vital role in vasodilation, the process of relaxing and widening blood vessels. This improved blood flow allows for more efficient delivery of oxygen and nutrients to muscles and organs. Because of its physiological effects, increasing nitric oxide levels is associated with several health benefits, including lower blood pressure, enhanced athletic endurance, and improved endothelial function. Diet is one of the most effective ways to naturally influence nitric oxide production, primarily by consuming foods rich in nitrates or amino acids like L-citrulline and L-arginine.

Leading Drinks for Boosting Nitric Oxide

Beetroot Juice: The Nitrate Powerhouse

Beetroot juice is arguably the most well-known drink for boosting nitric oxide, thanks to its exceptionally high concentration of dietary nitrates. When consumed, nitrates from beets are converted by bacteria in the mouth into nitrites, which are then converted into nitric oxide in the bloodstream. Research has repeatedly confirmed beetroot juice's efficacy, with studies showing significant increases in NO levels and subsequent improvements in blood pressure and exercise performance. The sustained nature of the NO increase and the relatively small volume needed make concentrated beetroot juice a highly convenient option.

Watermelon Juice: The Citrulline Supplier

Watermelon is one of nature's richest sources of the amino acid L-citrulline. The body converts L-citrulline into L-arginine, the primary substrate for nitric oxide production via the nitric oxide synthase enzyme. Research indicates that consuming watermelon juice can significantly improve nitric oxide bioavailability and enhance muscle oxygenation during exercise. However, achieving a high enough dose of citrulline from juice alone can sometimes be challenging, and some studies suggest that purified supplements might be more effective for boosting performance. The juice's hydrating properties and natural sweetness still make it a delicious and beneficial option.

Pomegranate Juice: The Antioxidant Protector

Pomegranate juice contains potent antioxidants called polyphenols, which play a different but equally important role in nitric oxide health. Instead of directly supplying nitrates, pomegranate's antioxidants protect the nitric oxide molecule from oxidative destruction, thereby increasing its total bioavailability in the body. This has been shown to enhance the vasodilation effects of NO and promote better blood flow. Studies have linked pomegranate juice to improvements in blood pressure and enhanced circulation, making it particularly beneficial for vascular health. For maximum effect, look for pure pomegranate juice with no added sugars.

Green Leafy Smoothies: A Nitrate-Rich Blend

Many leafy greens, including spinach, kale, and arugula, are also high in dietary nitrates and other beneficial compounds. A green smoothie is an excellent way to incorporate a large volume of these vegetables into a single drink. Combining them with other NO-boosting ingredients like beetroot powder and citrus fruits (which provide vitamin C to aid absorption) creates a powerful, nutrient-dense beverage. This approach offers the benefits of nitrates along with a wide array of vitamins, minerals, and antioxidants.

Comparison of Nitric Oxide Boosting Drinks

Drink Primary NO Mechanism Key Compounds Fast-Acting? Long-Term Effects? Ideal For Notes
Beetroot Juice Provides high levels of dietary nitrates Nitrates, Betalains Yes (within ~45 mins) Yes (sustained effects) Athletes needing pre-workout boost; individuals managing blood pressure Highly effective, but some dislike the taste
Watermelon Juice Provides L-citrulline, a precursor to L-arginine L-Citrulline, Lycopene Slower (body conversion required) Yes General cardiovascular health support May require a higher volume or more concentrated form for significant effects
Pomegranate Juice Antioxidants protect existing NO from degradation Polyphenols, Punicalagins Indirect Yes Promoting endothelial function and vascular longevity Protects NO, but doesn't directly create a large boost like nitrate-rich sources
Green Leafy Smoothies Supplies high dietary nitrates and antioxidants Nitrates, Vitamin C, Vitamins K/A Yes Yes All-around health, comprehensive nutrient intake Can combine with other ingredients for synergistic effects

A Sample Nitric Oxide Booster Smoothie Recipe

This recipe combines some of the most effective ingredients to maximize nitric oxide production and bioavailability.

  • Ingredients:

    • 1/2 cup pure beetroot juice (or 1 tbsp beetroot powder)
    • 1 cup fresh spinach or kale
    • 1/2 cup watermelon, chopped
    • 1/4 cup pure pomegranate juice
    • 1/2 banana (for thickness and sweetness)
    • 1/2 cup coconut water or almond milk
    • Juice of 1/2 a lemon
    • Handful of ice (optional)
  • Instructions:

    1. Combine all ingredients in a blender.
    2. Blend on high until smooth and creamy.
    3. Drink immediately to get the full benefits of the fresh ingredients.

Conclusion

While beetroot juice often takes the crown for a rapid and potent boost in nitric oxide due to its high nitrate content, the best drink for nitric oxide is really a matter of combining the right ingredients for your goals. For a quick pre-workout boost, beetroot is the go-to. For long-term vascular health, incorporating a variety of sources like pomegranate and watermelon juice alongside a diet rich in leafy greens is a smart strategy. The synergistic effects of these different compounds, whether by providing raw materials (nitrates, citrulline) or protecting the final product (antioxidants), offer a comprehensive way to naturally support your body's nitric oxide levels through your diet. A balanced nutritional approach provides more benefits than relying on a single ingredient or supplement. For more in-depth research on the effects of nitric oxide supplementation, see the study on watermelon juice effects on blood flow.

Frequently Asked Questions

Studies show that beetroot juice can significantly increase nitric oxide levels in the body within 45 minutes to a few hours of consumption.

Yes, combining different drinks can be highly effective. For example, blending nitrate-rich greens with pomegranate juice can both supply new nitric oxide precursors and protect the resulting nitric oxide from breakdown.

Concentrated juices or powders often provide a higher dosage of nitrates in a smaller volume, making it easier to consume the amount needed for a significant effect.

While these natural drinks are safe for most people, individuals with certain medical conditions, especially those on blood pressure medication, should consult a doctor before making significant dietary changes.

Yes, high-heat cooking can reduce the nitrate content in vegetables. Raw or minimally cooked forms, such as juicing raw beetroot or blending raw spinach, are best for preserving nitrates.

The conversion of nitrates to nitrites relies on specific bacteria on the tongue. Using antibacterial mouthwash can kill these beneficial bacteria and inhibit the nitric oxide production pathway.

Yes, eating the whole foods provides the same precursors, along with added fiber. However, drinking concentrated juice can deliver a higher dose in a smaller, more convenient serving.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.