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What is the difference between calcium phosphate and calcium citrate?

4 min read

The National Institutes of Health reports that absorption efficiency of calcium supplements depends heavily on the form and intake amount. Understanding the nuances between popular options like calcium phosphate and calcium citrate is crucial for maximizing your intake and supporting bone health effectively.

Quick Summary

Key factors differentiating calcium citrate and calcium phosphate include bioavailability, elemental calcium concentration, dependency on stomach acid, and potential for gastrointestinal side effects.

Key Points

  • Absorption Differences: Calcium citrate is highly bioavailable and absorbed without stomach acid, making it ideal for those on acid-reducing medication, while calcium phosphate is also well-absorbed and doesn't require food.

  • Elemental Content: Calcium phosphate contains a higher percentage of elemental calcium (approx. 39%) compared to calcium citrate (approx. 21%), meaning fewer tablets are needed for the same dose.

  • Gastrointestinal Effects: Both calcium citrate and calcium phosphate are generally well-tolerated and cause fewer gastrointestinal side effects like constipation and gas compared to calcium carbonate.

  • Cost: Calcium citrate is typically more expensive than calcium phosphate, which is in turn more expensive than the most common form, calcium carbonate.

  • Specific Uses: Calcium citrate is the preferred choice for those with low stomach acid, whereas calcium phosphate provides both calcium and phosphorus, which could benefit individuals with a phosphorus deficiency.

  • Dosage Matters: For optimal absorption, split doses of calcium into 500 mg or less of elemental calcium throughout the day, regardless of the supplement form.

In This Article

Calcium is a vital mineral that plays a critical role in bone health, nerve transmission, and muscle function. When diet alone doesn't provide enough, many turn to supplements. However, not all calcium supplements are created equal, and the key differences between various forms, such as calcium phosphate and calcium citrate, can significantly impact their effectiveness and suitability for different individuals.

Understanding Elemental Calcium

When comparing calcium supplements, it's essential to look at the amount of 'elemental calcium' they contain, not just the total weight of the compound. Elemental calcium is the amount of pure calcium available for your body to absorb. The percentage of elemental calcium varies greatly between different compounds, influencing how many pills you may need to take to meet your daily requirements. This factor, combined with absorption efficiency, is a primary differentiator between calcium phosphate and calcium citrate.

Calcium Citrate: The Easily Absorbed Option

Calcium citrate is a form of calcium supplement known for its high bioavailability, meaning the body can absorb it readily. It is particularly beneficial for certain populations for several key reasons:

  • Doesn't require stomach acid for absorption: Unlike calcium carbonate, calcium citrate is water-soluble and does not depend on an acidic stomach environment to be broken down and absorbed. This makes it an ideal choice for older adults and those taking acid-reducing medications like proton pump inhibitors or H2 blockers.
  • Can be taken with or without food: Because of its high solubility, calcium citrate can be taken at any time of day, offering more flexibility than supplements that must be taken with meals.
  • Lower risk of GI side effects: Calcium citrate is less likely to cause common gastrointestinal issues such as constipation, gas, and bloating compared to calcium carbonate.
  • Lower elemental calcium: A drawback of calcium citrate is that it contains less elemental calcium by weight (around 21%). This means you may need to take more tablets to achieve the same dose as a higher-concentration supplement.

Calcium Phosphate: The Concentrated Alternative

Calcium phosphate, available as tricalcium phosphate in most supplements, offers a different set of benefits, particularly regarding its mineral composition and elemental concentration.

  • Higher elemental calcium: Calcium phosphate provides a high concentration of elemental calcium, approximately 39%. This allows for a higher dose of calcium in fewer tablets, which can be a compliance advantage for some.
  • Contains phosphorus: Unlike calcium citrate, calcium phosphate naturally includes phosphorus, another mineral crucial for bone health. This makes it a potential choice for those who may have a phosphorus deficiency, although most individuals in developed countries get enough phosphorus from their diet.
  • Good tolerance: Calcium phosphate is generally well-tolerated and does not typically cause the gas and constipation issues associated with calcium carbonate.
  • Absorption not dependent on food: Similar to calcium citrate, calcium phosphate does not require food for optimal absorption.

Comparison Table: Calcium Citrate vs. Calcium Phosphate

Feature Calcium Citrate Calcium Phosphate
Elemental Calcium % ~21% ~39%
Absorption Highly bioavailable, does not require stomach acid Well-absorbed, does not require food
Stomach Acid Required No No
GI Side Effects Low risk of gas and constipation Low risk of gas and constipation
Cost Generally more expensive than phosphate More expensive than carbonate, but less than citrate
Best For Individuals with low stomach acid or on acid blockers Individuals needing high elemental calcium doses or with phosphorus deficiency

Factors Influencing Supplement Choice and Absorption

Beyond the intrinsic properties of the supplement form, several other factors can affect absorption and guide your choice:

  • Splitting doses: Regardless of the form, your body absorbs calcium most efficiently in doses of 500 mg of elemental calcium or less. If your daily intake exceeds this, it is best to split the dose throughout the day.
  • Vitamin D: Adequate vitamin D intake is crucial for calcium absorption. Many supplements, particularly combination products, include vitamin D to enhance this process.
  • Individual health: A person's specific health conditions, such as inflammatory bowel disease or history of kidney stones, can influence the best type of calcium supplement for them. Consulting a healthcare provider is essential for determining the most appropriate and safest option.

Conclusion

Choosing between calcium phosphate and calcium citrate comes down to a balance of individual health needs, absorption efficiency, and elemental concentration. Calcium citrate offers superior absorption for those with low stomach acid and is less likely to cause side effects, though it requires more tablets per dose. Calcium phosphate, with its higher elemental calcium content, is a concentrated alternative that may also be beneficial for those with phosphorus deficiency. The best approach is to consider your personal health profile and lifestyle before selecting a supplement.

For more information on calcium intake and requirements, see the NIH Fact Sheet on Calcium.

Frequently Asked Questions

Calcium citrate is generally considered to be highly bioavailable, especially for people with low stomach acid. Calcium phosphate is also well-absorbed and doesn't require food.

No, calcium citrate does not require stomach acid for absorption and can be taken effectively with or without food.

For optimal absorption, the body is most efficient at absorbing calcium in doses of 500 mg or less at one time. Split larger daily needs into multiple doses.

Compared to calcium carbonate, calcium phosphate is less likely to cause gas and constipation and is generally well-tolerated by the digestive system.

Someone might choose calcium phosphate for its higher elemental calcium content or if they have a diagnosed phosphorus deficiency, as it provides both minerals.

Yes, calcium citrate is generally more expensive than calcium carbonate and often more expensive than calcium phosphate.

Vitamin D is crucial for the body's active transport of calcium and for maintaining adequate calcium levels in the blood. Many calcium supplements include vitamin D for this reason.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.