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What Should Magnesium Be Taken With for Better Absorption?

4 min read

According to the NIH, a significant portion of the population may not meet the recommended daily intake of magnesium through diet alone. Maximizing the mineral's benefits means understanding what should magnesium be taken with for better absorption, including specific vitamins, minerals, and lifestyle factors.

Quick Summary

Taking magnesium with certain nutrients and following specific dietary practices can significantly improve its absorption. Pairing magnesium with vitamin D and vitamin B6, consuming it with food, and choosing the most bioavailable forms are all effective strategies. Avoiding absorption inhibitors like excessive calcium and high doses of zinc also plays a crucial role.

Key Points

  • Pair with Vitamin D and B6: Magnesium works synergistically with vitamin D and B6 to improve absorption and cellular utilization.

  • Take with Food: Consuming magnesium with a meal can increase absorption and prevent digestive side effects like diarrhea.

  • Choose Bioavailable Forms: Opt for highly absorbable forms like magnesium glycinate, citrate, or malate over less effective types like magnesium oxide.

  • Avoid Inhibitors: Separate high doses of calcium and zinc from your magnesium intake to prevent competitive absorption issues.

  • Support Gut Health: A healthy gut environment, fostered by prebiotics and probiotics, enhances overall nutrient uptake, including magnesium.

In This Article

Optimizing Your Magnesium Intake

Magnesium is an essential mineral involved in over 300 biochemical reactions in the body, impacting everything from nerve function and blood sugar control to muscle health and energy production. However, its absorption can vary depending on various factors, including the form of magnesium and what it is taken with.

Nutrient Partners That Enhance Absorption

One of the most effective ways to boost magnesium absorption is by creating a synergistic effect with other key nutrients. These nutritional partnerships help facilitate the mineral's journey from your digestive tract into your cells.

The Vitamin D Connection

Magnesium and vitamin D have a critical, interdependent relationship. Magnesium is required as a cofactor for the enzymes that activate vitamin D in your liver and kidneys. Without sufficient magnesium, vitamin D remains in an inactive storage form, essentially making it ineffective. In turn, active vitamin D stimulates proteins in the intestines that are responsible for transporting magnesium into the bloodstream, thereby increasing overall absorption.

The Role of B Vitamins and Zinc

  • Vitamin B6: This vitamin plays a key role in the cellular utilization of magnesium. It helps transport magnesium into the body's cells, ensuring it can perform its hundreds of functions effectively, especially in the muscles and nerves.
  • Zinc: While excessive doses of zinc can compete with and inhibit magnesium absorption, moderate amounts have a synergistic effect, supporting its transport within cells. It is important to maintain a healthy balance and, if supplementing with high doses of zinc, to take them at different times.

The Importance of Timing and Food

Magnesium absorption is not only about what you take but also when and how you take it.

Taking with Meals

For most people, it is beneficial to take magnesium supplements with a meal. This practice offers several advantages:

  • Prevents stomach upset: Some forms of magnesium, particularly less bioavailable ones like magnesium oxide, can cause digestive issues such as diarrhea and cramping when taken on an empty stomach.
  • Slows transit time: Having food in your gut slows down the digestive process, allowing more time for magnesium to be absorbed.

Mindful of Inhibitors

Just as certain nutrients enhance absorption, others can hinder it. To maximize your intake, be mindful of substances that interfere with magnesium uptake:

  • High-Dose Calcium: Calcium and magnesium compete for absorption pathways in the intestines. While both are essential, taking a large dose of calcium at the same time as magnesium can reduce the latter's absorption. For supplement users, spacing out calcium and magnesium doses is a good strategy.
  • High Fiber and Phytates: While fiber is important for gut health, high doses can bind to magnesium and reduce its absorption. Phytates, found in nuts, seeds, and whole grains, can also have this effect. Simply separating high-fiber meals from your magnesium supplement by a couple of hours is enough to avoid this interaction.

Bioavailability of Different Magnesium Forms

Not all magnesium supplements are created equal. Their bioavailability—the proportion of the mineral that is absorbed and utilized by the body—differs significantly depending on the form. Organic compounds are generally better absorbed than inorganic salts.

Comparison of Common Magnesium Forms

Magnesium Type Bioavailability Best For Potential Drawbacks
Glycinate High Promoting relaxation and sleep; gentle on the stomach Lower elemental magnesium content by weight
Citrate High Digestive health and relieving occasional constipation Possible laxative effect at higher doses
L-Threonate Very High (Brain) Enhancing cognitive function and memory More expensive; less research compared to other forms
Malate High Energy production and muscle fatigue Less calming effect than glycinate
Oxide Low Very limited absorption; mostly used as a laxative Poor bioavailability makes it ineffective for correcting deficiencies

Dietary Strategies and Gut Health

Beyond supplements, supporting magnesium absorption through diet and gut health is crucial. A healthy gut microbiome, supported by prebiotics and probiotics, can create a more favorable environment for mineral uptake.

Foods for Better Absorption

To naturally boost absorption, consume magnesium alongside foods rich in supporting nutrients:

  • Fatty Fish: Contains Vitamin D, which helps magnesium absorption.
  • Avocados: Offers healthy fats and Vitamin B6.
  • Yogurt: Provides probiotics for improved gut health.
  • Bananas: A source of Vitamin B6 and potassium.
  • Pumpkin Seeds: High in magnesium and also contain zinc.

Conclusion

For enhanced absorption, take magnesium with food and pair it with synergistic nutrients like vitamin D and B6. Choosing a highly bioavailable form, such as magnesium glycinate or citrate, is more effective than less soluble types like oxide for correcting deficiencies. Additionally, maintaining good gut health and being mindful of inhibitors like excessive calcium can optimize the benefits of this vital mineral. Always consult a healthcare provider before starting any new supplement regimen to determine the right dosage for your individual needs.

Frequently Asked Questions

Yes, taking magnesium and vitamin D together can be beneficial. Magnesium is necessary to activate vitamin D in the body, and vitamin D helps transport magnesium across the intestinal wall, creating a synergistic effect that boosts absorption.

It is generally recommended to take magnesium with food to improve absorption and prevent potential side effects like nausea or diarrhea. Taking it with a meal slows down digestion, allowing more time for absorption.

Pairing magnesium with foods rich in vitamin B6 (avocado, bananas) and vitamin D (fatty fish, eggs) can enhance absorption. Probiotic-rich yogurt also supports a healthy gut environment, which aids mineral uptake.

Highly bioavailable forms like magnesium glycinate, citrate, and malate are better absorbed by the body than less soluble forms such as magnesium oxide. Magnesium glycinate is often recommended for sensitive stomachs.

High doses of calcium can compete with magnesium for absorption in the intestines. If you take supplements of both, it is often best to space them out throughout the day to optimize the absorption of each mineral.

Factors that can inhibit magnesium absorption include excessive calcium intake, high doses of zinc, excessive caffeine and alcohol, and a diet very high in phytates and oxalates (found in some whole grains and leafy greens).

The consistency of taking magnesium is more important than the specific time of day. However, some prefer magnesium in the evening for relaxation, while others take it in the morning for sustained energy, depending on the form and individual goals.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.