Skip to content

What to do if your folate levels are low: Treatment, diet, and next steps

4 min read

A folate deficiency, which can be diagnosed through a blood test, can lead to various health complications, including a specific type of anemia called megaloblastic anemia. Knowing what to do if your folate levels are low is crucial for restoring your energy and overall well-being.

Quick Summary

Low folate levels can cause fatigue and weakness. Address a deficiency with dietary changes, folic acid supplements, and by treating any underlying health conditions.

Key Points

  • Consult a Doctor: A healthcare professional can confirm a folate deficiency with a blood test and rule out a co-existing vitamin B12 deficiency.

  • Increase Folate-Rich Foods: Incorporate dark leafy greens, legumes, and fortified grains into your diet to naturally boost folate intake.

  • Consider Supplements: Most people are prescribed folic acid tablets to quickly restore folate levels over a period of a few months.

  • Check Vitamin B12 Levels: Always check your vitamin B12 levels before starting folic acid treatment, as high folate intake can mask a B12 deficiency.

  • Address Underlying Causes: If a condition like celiac disease or excessive alcohol use is causing the deficiency, it must be treated to ensure long-term recovery.

  • Monitor Symptoms: Pay attention to symptoms like fatigue, paleness, or mouth sores, which can signal a folate deficiency.

In This Article

Understanding Folate Deficiency

Folate, or vitamin B9, is an essential nutrient needed for many vital bodily functions, including the production of red blood cells and the synthesis of DNA. When your body doesn't get enough folate, it can lead to a folate deficiency, which can have noticeable effects on your health.

Common causes of low folate levels include a diet poor in folate-rich foods, excessive alcohol consumption, and certain health conditions such as celiac disease or kidney disease. Some medications, like those for epilepsy, can also interfere with folate absorption. Pregnancy is another period of increased folate requirement, and a deficiency can lead to severe birth defects.

Recognizing the Symptoms

Symptoms of a folate deficiency often develop gradually and can be subtle at first. Since folate is critical for red blood cell production, many of the signs are related to anemia. These include:

  • Fatigue and lack of energy: A common and early symptom.
  • Paleness: Especially in the skin, gums, or nails.
  • Sore and red tongue: Known as glossitis.
  • Mouth ulcers or sores: Painful sores may appear in the mouth.
  • Irritability: Mood changes can occur.
  • Neurological issues: In more severe cases, problems with memory, concentration, and judgment may arise.

If you experience any of these symptoms, it's important to see a healthcare provider for a proper diagnosis through a blood test.

Dietary Strategies to Increase Folate Intake

One of the most effective ways to treat and prevent low folate levels is to increase your consumption of folate-rich foods. A varied and healthy diet can provide your body with the nutrients it needs to produce healthy red blood cells.

Folate-Rich Foods List

Here are some excellent sources of folate that you can incorporate into your daily meals:

  • Legumes: Lentils, black beans, chickpeas, and edamame.
  • Dark Leafy Greens: Spinach, romaine lettuce, asparagus, and broccoli.
  • Fortified Grains: Enriched breads, cereals, pasta, and rice often have folic acid added to them.
  • Fruits: Oranges, bananas, papayas, and avocados are good sources.
  • Nuts and Seeds: Peanuts, walnuts, and sunflower seeds contain folate.
  • Animal Products: Beef liver, seafood, eggs, and dairy also contain folate.

Since folate is sensitive to heat, cooking methods can affect its content. Steaming vegetables rather than boiling them can help preserve more of the folate.

Supplementing with Folic Acid

In addition to dietary changes, many people require supplementation to quickly restore their folate levels. Folic acid is the synthetic, more stable, and highly absorbable form of folate found in supplements and fortified foods. A healthcare provider will determine the appropriate supplementation approach and duration based on the severity of the deficiency and individual needs. Most people need to take supplements for several months to replenish their body's stores.

Folate vs. Folic Acid

While the terms are often used interchangeably, folate and folic acid are different forms of vitamin B9. Their primary difference lies in their source and how they are absorbed by the body. Read more on the distinction between the two from the National Institutes of Health.

Feature Folate (Natural) Folic Acid (Synthetic)
Source Found naturally in foods like leafy greens, legumes, and citrus fruits. Found in supplements and added to fortified foods like enriched grains.
Absorption Generally less stable and less readily absorbed by the body; absorption can be affected by cooking. Highly stable and easily absorbed by the body; absorption rate is high.
MTHFR gene Individuals with a certain MTHFR gene variant may have difficulty converting some forms of folate, but can still process folic acid. Effective even for those with an MTHFR variant, as it provides a direct source of B9.
Use Contributes to the daily nutrient intake from a balanced diet. Used for supplementation and food fortification to prevent deficiencies and associated health issues.

When to See a Doctor

It is crucial to consult a healthcare provider if you suspect a folate deficiency. A doctor can confirm the diagnosis with a blood test and rule out other potential deficiencies, especially a vitamin B12 deficiency. High-dose folic acid supplementation can mask a vitamin B12 deficiency, which could lead to irreversible nerve damage if left untreated. A doctor will also investigate and address any underlying causes, such as malabsorption issues or medication side effects.

Treating Underlying Causes

Addressing the root cause of the deficiency is as important as correcting the low folate levels themselves. This might involve:

  • Treating celiac disease: If a malabsorption issue is diagnosed, treating the underlying digestive disorder will be necessary.
  • Managing alcohol intake: Excessive alcohol consumption can interfere with folate absorption.
  • Adjusting medications: Your doctor may review your current medications and adjust them if they are the cause of the deficiency.

Conclusion: A Proactive Approach to Low Folate

Managing low folate levels is a straightforward process involving a combination of dietary adjustments and supplementation, guided by a healthcare professional. By incorporating more folate-rich foods into your diet and taking prescribed folic acid supplements, you can effectively restore your body's folate stores. Early detection and treatment are key to preventing the symptoms and long-term complications associated with a folate deficiency. Remember to consult your doctor for a proper diagnosis and treatment plan tailored to your specific needs, ensuring your overall health and well-being.

Frequently Asked Questions

Common symptoms include fatigue, a lack of energy, pale skin, a sore or red tongue, mouth ulcers, irritability, and in severe cases, neurological issues.

Excellent sources of folate include legumes (lentils, beans), dark leafy greens (spinach, asparagus), fortified cereals and grains, oranges, and avocados.

Folate is the naturally occurring form of vitamin B9 found in food, while folic acid is the synthetic form used in supplements and fortified foods, which is more readily absorbed by the body.

In most cases, a doctor will prescribe daily folic acid tablets to restore folate levels, especially if diet alone is insufficient to correct the deficiency.

Yes, a folate deficiency can lead to folate-deficiency anemia (also known as megaloblastic anemia), which results from the body producing abnormally large, poorly functioning red blood cells.

You can prevent low folate levels by eating a balanced diet rich in folate-containing foods and fortified grains. Women of childbearing age should also consider taking a daily folic acid supplement.

It's essential to check vitamin B12 levels because high-dose folic acid can correct the anemia symptoms of a B12 deficiency, but it will not treat the neurological damage, potentially allowing it to worsen undetected.

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.