Common Causes of Wine Headaches
Many people experience headaches after drinking wine, especially red wine, and several compounds are thought to be the culprits. However, the specific trigger can vary significantly from person to person.
Histamines
Histamines are natural compounds found in the skins of grapes, which are released during the fermentation process. Because red wines are fermented with the grape skins, they contain significantly higher levels of histamines than white wines, which are fermented with only the grape juice. In some individuals, particularly those with a sensitivity, high histamine levels can trigger symptoms like headaches, flushing, and sneezing. Taking a non-drowsy antihistamine before drinking has been anecdotally reported to help mitigate these effects.
Tannins
Tannins are polyphenols found in grape skins, seeds, and stems, which give wine its structure and a dry, mouth-puckering sensation. Red wines have higher tannin levels than white wines due to longer contact with the grape skins during fermentation. Some research suggests that tannins can cause a release of serotonin in the brain, which can induce headaches in certain people. Lighter, younger reds and most white wines will have lower tannin levels.
Sugar and Alcohol Content
High sugar content, especially in combination with high alcohol, can exacerbate headaches through dehydration. Alcohol is a diuretic, causing the body to lose fluids, and high-sugar wines compound this effect. When the body is already working to process alcohol, extra sugar can accelerate dehydration. Choosing drier wines with lower alcohol content, generally below 13% ABV, can help minimize these effects.
Sulfites and Additives
While often blamed for wine headaches, sulfites are not the primary cause for most people. A small percentage of the population has a severe sulfite allergy, which typically manifests as breathing problems or hives, not a headache. White wines often contain more added sulfites than reds to preserve their freshness, yet they are less frequently associated with headaches. However, mass-produced conventional wines may contain a variety of other additives that can affect sensitive drinkers. Some studies have suggested that in natural wines with less or no added SO2, there may be higher levels of biogenic amines, another potential headache trigger.
Which Wines are Least Likely to Trigger Headaches?
To minimize the risk of a wine headache, consider the following choices:
- White Wines: Generally lower in tannins and histamines than their red counterparts, white wines are a safer bet for many sensitive drinkers. Crisp options like unoaked Sauvignon Blanc or Pinot Grigio are excellent choices.
- Low-Tannin Red Wines: If you prefer red, opt for varieties made from thin-skinned grapes. Good examples include Pinot Noir, Gamay (Beaujolais), and Barbera. These wines offer fruit-forward flavors with a smoother texture.
- Organic and Biodynamic Wines: These wines typically contain minimal additives and lower levels of added sulfites, though they may contain higher amounts of other compounds like biogenic amines. Many sensitive drinkers report better experiences with these selections.
- Low-Alcohol Wines: Wines below 13% ABV will be less dehydrating. Look for labels that list alcohol content and choose a lighter option. German Rieslings, for example, are known for their lower alcohol content.
How to Drink Wine and Avoid a Headache
Besides choosing the right wine, several habits can help you enjoy a glass without the pain:
- Stay Hydrated: Drink a glass of water for every glass of wine you consume.
- Eat While You Drink: Food helps slow the absorption of alcohol, reducing its impact.
- Drink in Moderation: Limiting your intake is the most surefire way to avoid any alcohol-related headache.
Comparison of Wines for Headache Sensitivity
| Wine Type | Histamine Levels | Tannin Levels | Sugar Levels | Potential for Headache | 
|---|---|---|---|---|
| Crisp White Wine (e.g., Sauvignon Blanc, Pinot Grigio) | Low | Low | Low (Dry) | Low | 
| Light-Bodied Red Wine (e.g., Pinot Noir, Gamay) | Moderate | Low | Low (Dry) | Medium-Low | 
| Full-Bodied Red Wine (e.g., Cabernet Sauvignon, Shiraz) | High | High | Varies | High | 
| Sweet Wine (e.g., Dessert Wines) | Varies | Varies | High | Medium-High | 
| Organic/Natural Wine | Variable (often higher biogenic amines) | Low-Medium | Low (Dry) | Varies (Individual Sensitivity) | 
Conclusion
For those sensitive to wine-induced headaches, selecting the right bottle requires paying attention to key components like histamines, tannins, and sugar. The safest choices are typically dry white wines, like Sauvignon Blanc or Pinot Grigio, and lighter reds, such as Pinot Noir or Gamay, as they generally contain lower levels of these triggering compounds. Equally important are smart drinking habits, including hydration and moderation, which play a significant role in preventing discomfort. By being mindful of your triggers and making informed choices, you can enjoy wine with less risk of a headache.
Expert Recommendations for Sensitive Drinkers
To enjoy wine without the unwelcome side effects, consider focusing on lighter, fresher options and responsible consumption habits.
- Prioritize unoaked white wines: These wines have lower histamine and tannin content, reducing the likelihood of a headache.
- Choose light-bodied reds from thin-skinned grapes: Opt for Pinot Noir, Gamay, or Barbera over heavier reds like Cabernet Sauvignon.
- Ensure you stay hydrated: Alternate between glasses of wine and water to combat dehydration, a primary cause of alcohol-related headaches.
- Select drier wines with lower residual sugar: This helps to avoid the blood sugar fluctuations that can trigger headaches.
- Eat before and while drinking wine: Food can help slow alcohol absorption, mitigating its impact on your body.
- Experiment with different producers and regions: Not all wines of the same varietal are created equal. Trying options from different winemakers can help you pinpoint personal sensitivities.
Authoritative Source for Further Reading
For more in-depth information on wine headaches and their causes, a review of recent studies was published in Scientific Reports.
: https://www.dailymail.co.uk/health/article-12771203/Scientists-discover-people-headaches-drinking-red-wine-expensive-bottles-likely-cause-them.html : https://www.medicalnewstoday.com/articles/headaches-after-drinking-red-wine-flavanols-quercetin : https://hopefamilywines.com/why-do-some-wines-give-me-a-headache/ : https://kindofwildwines.com/blogs/blog/a-guide-to-avoid-the-wine-headache : https://brainhealthct.com/2409-2/ : https://daily.sevenfifty.com/what-new-research-about-wine-headaches-means-for-natural-wine/ : https://fermentationwineblog.com/2021/12/natural-wine-causes-more-headaches-for-wine-drinkers-and-natural-wine/ : https://www.health.harvard.edu/diseases-and-conditions/ask-the-doctor-what-causes-red-wine-headaches : https://www.foodandwine.com/wine/red-wine/why-does-wine-give-you-headache : https://www.drinkvinito.com/blogs/wine-tips/low-tannin-red-wines : https://boundbywine.com/collections/no-or-light-tannin-wines : https://kindofwildwines.com/blogs/blog/a-guide-to-avoid-the-wine-headache : https://www.reddit.com/r/wine/comments/1harh4g/red_wine_suggestions_headaches/ : https://www.winemag.com/recipe/wine-suggestions-from-michael-green/ : https://pullthecork.co.uk/why-do-some-wines-give-you-a-headache/ : https://www.youtube.com/watch?v=zIeHupLQaJo : https://www.foodandwine.com/wine/red-wine/why-does-wine-give-you-headache : https://www.bunnycupwinery.com/blog/The-Truth-about-Sulphates-in-winemaking--do-they-really-cause-headaches- : https://health.clevelandclinic.org/wine-headache : https://minuman.com/blogs/all/low-tannin-red-wine