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What's Better, AG1 or Seed? A Comprehensive Supplement Comparison

4 min read

According to a 2025 Healthline dietitian's take, Seed and AG1 are fundamentally different supplements, with Seed focusing on prebiotics and probiotics while AG1 offers a broad greens-based formula. Determining what's better, AG1 or Seed, depends entirely on whether you need a comprehensive nutritional boost or a targeted gut health solution.

Quick Summary

This article provides a head-to-head comparison of AG1 and Seed DS-01, detailing their ingredients, specific benefits, costs, and primary focus to help consumers make an informed decision based on their individual health objectives.

Key Points

  • Purpose: AG1 is a broad, all-in-one greens and nutrient supplement, while Seed DS-01 is a highly specific, targeted synbiotic for gut health.

  • Ingredients: AG1 features 75+ ingredients, including vitamins, minerals, and adaptogens, while Seed contains 24 clinically-studied probiotic strains and a prebiotic.

  • Cost: AG1 is significantly more expensive per serving (~$3.30 vs ~$1.67), making Seed the more budget-friendly option for targeted gut health.

  • Probiotic Potency: Seed DS-01 provides a higher, clinically-researched dose of specific strains, measured in AFUs, ensuring potency and efficacy for gut health.

  • Transparency: Seed offers greater transparency by detailing its specific probiotic strains, whereas AG1 uses proprietary blends, which obscures exact ingredient doses.

In This Article

What is AG1?

AG1, formerly known as Athletic Greens, is a comprehensive nutritional supplement in a powder format, designed to replace multiple supplements in one daily scoop. It boasts a formula with over 75 vitamins, minerals, and whole-food sourced ingredients, targeting foundational health pillars like energy, immunity, and hormonal support.

AG1 is not just a greens powder; it also includes adaptogens to help manage stress, a nutrient-dense complex, and a digestive enzyme and super mushroom complex. The formula is NSF Certified for Sport, a significant third-party certification that verifies safety and quality. It is vegan, non-GMO, and free from gluten and artificial ingredients, making it suitable for a range of dietary patterns. However, a key limitation noted by dietitians is the use of proprietary blends, which means the exact dosage of many ingredients is not disclosed, making it hard to evaluate their efficacy. The inclusion of probiotics is also part of a larger blend, which contrasts with Seed's specialized, targeted approach.

What is Seed DS-01 Daily Synbiotic?

Seed DS-01 is a daily synbiotic—a supplement that combines a probiotic with a prebiotic—focused specifically on gut health. It is a two-in-one capsule designed to ensure the probiotic strains survive the digestive process and reach the colon intact. Seed's formulation is backed by extensive scientific research and is transparent about its contents, detailing the 24 specific probiotic strains and their clinically verified potencies (measured in AFUs, or Active Fluorescent Units).

Unlike AG1's broad spectrum of vitamins and nutrients, Seed's purpose is singular and focused: to support the gut microbiome for improved digestive health. Seed DS-01 is third-party tested and adheres to strict quality and testing standards, exceeding U.S. requirements. While it contains a powerful and well-researched probiotic, it does not offer the wide array of vitamins, minerals, or adaptogens found in AG1. For individuals with existing vitamin routines or those whose primary concern is gut health, this targeted approach can be a major advantage.

AG1 vs. Seed: Head-to-Head Comparison

Feature AG1 (Greens Powder) Seed DS-01 (Daily Synbiotic)
Primary Purpose Comprehensive foundational nutrition, multi-nutrient support. Targeted gut microbiome and digestive health support.
Ingredients 75+ vitamins, minerals, adaptogens, superfoods, and some probiotics. 24 clinically-studied probiotic strains plus prebiotic fiber.
Format Powder mixed with water. Capsule-in-capsule system.
Probiotic Focus Includes a modest amount of probiotics as part of a larger formula. Exclusive, high-potency focus on specific, clinically-backed strains.
Third-Party Testing NSF Certified for Sport. Adheres to FDA requirements, exceeds US standards.
Cost (approximate) ~$3.30 per serving (subscription). ~$1.67 per serving (subscription).
Transparency Uses proprietary blends for some complexes, obscuring ingredient amounts. Highly transparent, detailing specific strains, potencies, and benefits.
Best For Individuals seeking an all-in-one nutritional boost to fill gaps. Those specifically targeting gut health with a premium, researched probiotic.

Which Supplement is Right for You?

Choosing between AG1 and Seed DS-01 requires evaluating your personal health goals and priorities. There is no universally 'better' product, as they serve different needs effectively. The ideal choice depends on what you're hoping to achieve with your supplement routine.

Choose AG1 if:

  • You want an all-in-one supplement: AG1's comprehensive formula can replace a multivitamin, separate probiotics, and other foundational supplements, simplifying your daily routine.
  • You need general nutritional support: If your diet is inconsistent, AG1 provides a wide safety net of vitamins, minerals, and superfoods to help fill potential nutrient gaps.
  • You are an athlete: The NSF Certified for Sport status ensures it's free of banned substances, making it a safe choice for competitive athletes.

Choose Seed DS-01 if:

  • Your primary concern is gut health: If you already take a multivitamin or have a generally healthy diet, Seed offers a highly targeted, potent, and scientifically backed probiotic for optimal gut microbiome support.
  • You prefer dosage transparency: Seed discloses the exact strains and quantities in its formula, providing confidence that you are getting clinically-backed doses.
  • You are cost-conscious about specific needs: Seed is less expensive per serving than AG1, and is the better value if your sole goal is premium probiotic support, rather than a broad-spectrum supplement.

Conclusion: The Right Choice is a Personal One

Ultimately, the question of what's better, AG1 or Seed, is a question of purpose. AG1 is the Swiss Army knife of supplements, offering a broad range of nutritional support in one drink, albeit at a higher cost and with less ingredient transparency. Seed DS-01 is a precision-engineered tool for a single, vital purpose: optimizing gut health with a research-backed, high-potency synbiotic. Before starting any new supplement, consider your current diet, health goals, and budget, and consult a healthcare professional to ensure the product is right for you. For more information on the efficacy and safety of different probiotic strains, consulting a reliable medical resource like the National Institutes of Health can be beneficial.

Frequently Asked Questions

Seed DS-01 is likely more effective for targeted gut health. While AG1 includes probiotics, Seed is a specialized synbiotic formulated with a greater variety of clinically-studied strains and a specific delivery system to ensure potency and survival through the digestive tract.

AG1 holds the NSF Certified for Sport designation, which means it has been tested for banned substances, making it a safer and more comprehensive option for competitive athletes who need broad nutritional support.

The value depends on your needs. AG1 offers a wider range of ingredients for a higher price. Seed provides a highly focused, premium probiotic for significantly less money per serving, offering better value if your goal is exclusively gut health.

Consulting a healthcare professional is best before combining supplements. Since both contain probiotics, it's possible to over-supplement or for the strains to interact. However, some people may use AG1 for overall nutrition and Seed for a more targeted probiotic boost.

Neither supplement is a replacement for a healthy diet rich in whole foods, fruits, and vegetables. They are designed to complement and support your nutritional intake, not to replace meals or balanced eating habits.

Some users of AG1 report mild digestive issues like bloating or stomach upset, particularly when first starting. Similarly, some Seed users experience initial bloating or gas as their body adjusts to the new probiotic strains.

No, the FDA does not approve supplements in the way it does drugs. However, Seed does adhere to FDA requirements regarding ingredients and claims, and performs testing that exceeds US standards.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.