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What's the best supplement to take at night?

4 min read

Over one-third of American adults report not getting enough sleep on a regular basis. For those seeking a natural edge, understanding what's the best supplement to take at night is the first step toward achieving better, more restorative rest.

Quick Summary

This guide compares popular nighttime supplements, including magnesium, melatonin, L-theanine, and ashwagandha. It breaks down their individual benefits for relaxation and sleep to help you make an informed choice.

Key Points

  • Magnesium Glycinate: Ideal for physical and mental relaxation and stress-related tension.

  • Melatonin: Best for resetting your circadian rhythm due to jet lag or shift work, not for chronic insomnia.

  • Ashwagandha: An adaptogenic herb that helps lower cortisol to combat stress-induced sleeplessness.

  • L-Theanine: Promotes a calm, non-drowsy mental state by boosting alpha brain waves, perfect for an overactive mind.

  • Glycine: An amino acid that helps lower core body temperature, a key mechanism for promoting sleep.

  • Timing Matters: Avoid stimulating supplements like B12 and high-dose multivitamins at night to prevent sleep disruption.

  • Choose Wisely: Look for third-party tested products to ensure quality, and consult a healthcare provider before starting any new regimen.

In This Article

Understanding Your Nighttime Needs

Before choosing a supplement, it's crucial to identify the root cause of your sleep problems. Are you looking for something to help you fall asleep faster, or to improve the quality of your deep sleep? Is stress keeping you up, or is it muscle tension after a hard workout? Different supplements target different issues, so matching the solution to the problem is key.

Leading Nighttime Supplement Options

Magnesium

Magnesium is a mineral involved in over 300 biochemical reactions in the body, many of which are related to sleep and relaxation. It helps regulate neurotransmitters that quiet the nervous system, and studies suggest it can improve sleep quality and reduce insomnia severity, especially in older adults.

  • Magnesium Glycinate: A form of magnesium bound with glycine, an amino acid with calming properties. It's known for being gentle on the stomach and is a top choice for promoting physical and mental relaxation.
  • Magnesium L-Threonate: This unique form can cross the blood-brain barrier more effectively, potentially offering more direct benefits for brain health, cognitive function, and the regulation of sleep cycles.

Melatonin

Melatonin is a hormone your body naturally produces to regulate the sleep-wake cycle. It signals to the body that it's time to sleep. Supplemental melatonin is most effective for conditions related to circadian rhythm disruption, such as jet lag, delayed sleep-wake phase disorder, or shift work.

  • Usage: Low amounts are often sufficient and can be taken before bed. Taking more is not necessarily more effective and can lead to side effects like grogginess the next day.
  • Safety: Melatonin is generally considered safe for short-term use, but long-term safety data is limited. It can also interact with certain medications, including blood thinners and antidepressants.

L-Theanine

Found primarily in green tea, L-theanine is an amino acid that promotes relaxation without sedation. It works by increasing alpha brain waves, which are associated with a state of calm alertness, and boosts calming neurotransmitters like GABA. It can improve sleep quality, but it won't knock you out like a sedative. It's a great option for individuals whose sleep is disrupted by stress or an overactive mind.

  • Usage: Research suggests effective use involves taking L-theanine before bedtime.

Ashwagandha

Ashwagandha is an adaptogenic herb used in Ayurvedic medicine to help the body manage stress. High cortisol levels from chronic stress can disrupt sleep. Ashwagandha has been shown to reduce cortisol, which can help improve sleep quality, especially for those experiencing stress-related insomnia.

  • Forms and Timing: Supplements often use root extract (like KSM-66) or root and leaf extracts (like Shoden). It may take several weeks of consistent use to see significant effects on sleep and stress levels.

Comparing Top Nighttime Supplements

Supplement Primary Benefit Best For Onset Considerations
Magnesium Glycinate Relaxation, muscle tension Stress-related tension, general relaxation 1-2 weeks for effects Very gentle on the digestive system
Melatonin Regulates sleep-wake cycle Jet lag, shift work, delayed sleep phase Relatively quick Start with low amount; short-term use recommended
L-Theanine Mental calmness, focus Racing mind, stress-related sleep disruptions Relatively quick Promotes relaxation without sedation
Ashwagandha Stress reduction, cortisol lowering Insomnia linked to chronic stress Several weeks for significant results Long-term safety data is limited
Glycine Lowers body temperature for sleep Improving sleep quality, reducing daytime sleepiness Relatively quick Can be effective

What to Avoid at Night

Just as important as knowing what to take is understanding what to avoid. Some supplements are energizing and can disrupt your sleep cycle.

  • Vitamin B12: This vitamin is crucial for energy production, and taking it at night can stimulate the central nervous system, interfering with sleep.
  • Vitamin C: While beneficial, its stimulating properties can cause excitability and gastrointestinal discomfort for some when taken too close to bedtime.
  • High-Dose Multivitamins: Many multivitamins contain B vitamins and can be stimulating. They are also often best taken with food for optimal absorption of fat-soluble vitamins, making them a better morning choice.

Considerations and Precautions

Before starting any new supplement regimen, especially if you have pre-existing health conditions or are taking other medications, it's essential to consult a healthcare provider. The supplement industry is not tightly regulated by the FDA, so choosing products that are third-party tested by organizations like NSF or ConsumerLab.com is wise to ensure product quality and accurate labeling. Always follow label directions.

The Final Verdict: Choosing the Best Nighttime Supplement

Ultimately, there is no single best supplement for everyone, but rather the best option for your individual needs. If stress and tension are your primary culprits, magnesium glycinate or ashwagandha are excellent choices. If you're struggling to regulate your sleep-wake cycle due to travel or an irregular schedule, melatonin is a targeted option for short-term use. For those with a racing mind that prevents sleep, L-theanine can provide a calm state of mind. Combining certain supplements, like L-theanine with magnesium, can also produce synergistic effects. Listening to your body and consulting with a professional is the surest path to discovering your best nighttime supplement. For more information on safe practices and sleep hygiene, consider reviewing resources from the Sleep Foundation.

Frequently Asked Questions

Identify your primary sleep issue first. If it's stress, consider ashwagandha or magnesium. For an overactive mind, L-theanine may be best. If it's a disrupted sleep-wake cycle, try melatonin for short-term use.

Yes, many people combine them. Magnesium helps with relaxation, while melatonin regulates the sleep cycle. However, always check with a healthcare provider to ensure there are no contraindications with your specific health status or other medications.

Yes. Melatonin can cause next-day grogginess or vivid dreams, especially with higher amounts. Some forms of magnesium may cause digestive issues with higher amounts. Always start with a lower amount to assess your tolerance.

Expert consensus suggests melatonin is safe for short-term use, but long-term safety data is limited. It's recommended to address the underlying cause of sleep issues rather than relying on a supplement indefinitely.

Magnesium glycinate is often recommended for sleep due to its relaxing effects and high bioavailability, along with the calming amino acid glycine. Magnesium L-threonate is a good alternative for those also seeking cognitive support.

Ashwagandha is an adaptogen and its effects are not immediate. Many studies show significant benefits for sleep and stress after a few weeks of consistent, daily use.

Yes, it is highly recommended to speak with a healthcare provider, especially if you are pregnant, breastfeeding, have pre-existing conditions, or are taking other medications, as supplements can interact with prescription drugs.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.