Common Herbs High in Coumarin
Coumarin is present in various herbs and plants, with concentrations varying widely. Cassia cinnamon is a well-known source, containing significantly higher levels than Ceylon cinnamon. Other plants with notable coumarin content include tonka beans, sweet clover, and sweet woodruff.
Cassia Cinnamon
This common, inexpensive cinnamon (Cinnamomum cassia) found in many grocery stores has coumarin levels up to 10,000 mg/kg. Due to this high concentration, health authorities advise against excessive consumption, particularly for children and sensitive individuals who could exceed the tolerable daily intake (TDI).
Sweet Clover
Historically used in herbal medicine, sweet clover (Melilotus officinalis) contains a coumarin glycoside. When dried or wilted, this can convert into the anticoagulant dicumarol, which caused hemorrhagic disease in livestock. Dried sweet clover can have a coumarin concentration of 0.4% to 1%.
Sweet Woodruff
Sweet woodruff (Galium odoratum) is used to flavor drinks and, like sweet clover, releases coumarin and its characteristic scent primarily when dried.
Other Notable Plants
Other plants containing coumarin include Tonka beans (very high levels), lavender, green tea, celery and parsley (containing furanocoumarins), fenugreek, licorice root, and citrus peels (bergamot, grapefruit, lemon) which contain coumarins and furanocoumarins.
Health Implications of Coumarin
Moderate dietary coumarin intake is generally safe for most people. The European Food Safety Authority (EFSA) sets a Tolerable Daily Intake (TDI) of 0.1 mg/kg body weight. Risks arise with very high consumption of Cassia cinnamon or concentrated herbal supplements over time.
The primary concern is liver damage, which is typically reversible. In most people, coumarin is metabolized into a harmless compound, but in sensitive individuals or those with reduced CYP2A6 enzyme activity, a potentially toxic metabolite can be produced.
Table: Coumarin Content Comparison
| Herb Source | Botanical Name | Coumarin Level (Typical Range) | Primary Use | Associated Health Risks (High Intake) |
|---|---|---|---|---|
| Cassia Cinnamon | Cinnamomum cassia | Very High (up to 10,000 mg/kg) | Spice, flavoring | Liver damage, especially in sensitive individuals |
| Ceylon Cinnamon | Cinnamomum verum | Very Low (trace amounts) | "True" cinnamon, baking | Generally considered safe for moderate to high intake |
| Sweet Clover | Melilotus officinalis | High (0.4–1%) | Herbal remedy, anticoagulant precursor | Liver damage, hemorrhagic disease (when dried/fermented) |
| Sweet Woodruff | Galium odoratum | High (when dried) | Flavoring agent (drinks) | Liver damage with high intake |
| Tonka Bean | Dipteryx odorata | Very High (1–3%) | Fragrance, flavoring | Liver damage, restricted in food use in some regions |
| Celery | Apium graveolens | Low (furanocoumarins) | Culinary herb | Photosensitivity with high intake |
Recommended Precautions and Alternatives
To minimize potential risks, especially for those with liver issues, consider these steps:
- Choose Ceylon Cinnamon: Use Ceylon cinnamon, which has minimal coumarin, particularly for frequent consumption. Always check product labels.
- Moderate Intake: Limit high-coumarin foods if you regularly consume large amounts of items like baked goods with Cassia cinnamon.
- Consult a Professional: If you have liver disease or are on anticoagulant medication, speak to a healthcare provider before using coumarin-rich herbs or supplements.
Conclusion
Coumarin is a natural compound in many plants and herbs, including Cassia cinnamon, sweet clover, and sweet woodruff. While generally safe in moderation, high intake, particularly from Cassia cinnamon, can pose a risk of liver damage for some individuals. Choosing low-coumarin alternatives like Ceylon cinnamon and being mindful of consumption levels are key to enjoying the flavors of these herbs while minimizing potential health concerns. For most people, dietary coumarin is within safe limits, but awareness allows for informed choices about herbal and spice use.
The European Food Safety Authority (EFSA) provides detailed information on coumarin metabolism and safety.