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Which Magnesium Gets Rid of Headaches? A Guide to Effective Forms

4 min read

Research suggests that up to 50% of individuals with migraines may be deficient in magnesium, a vital mineral involved in over 300 biochemical reactions in the body. Selecting the right type of magnesium can be key to helping reduce the frequency and severity of headaches for many people.

Quick Summary

Different forms of magnesium offer unique benefits for headache and migraine prevention based on absorption and tolerability. Understanding the distinctions between options like magnesium glycinate, oxide, and citrate can help in selecting the most effective supplement for your specific needs, focusing on preventive strategies over acute relief.

Key Points

  • Magnesium Deficiency: Many migraine sufferers have low levels of magnesium, contributing to heightened nerve excitability and blood vessel changes.

  • Magnesium Glycinate: A highly bioavailable and gentle form, often recommended for overall headache prevention, anxiety, and sleep improvement without causing significant digestive upset.

  • Magnesium Oxide: An inexpensive option that is effective in some studies for migraine prophylaxis, but has low absorption and a strong laxative effect.

  • Magnesium Citrate: Highly absorbable and works well for migraine prevention, but its laxative properties can cause diarrhea and may not suit everyone.

  • Long-term Prevention: The effectiveness of magnesium supplements, regardless of the form, relies on consistent daily intake over several weeks or months, rather than immediate, acute relief.

  • Consult a Doctor: It's crucial to consult a healthcare provider before starting a magnesium supplement, especially with pre-existing conditions like kidney problems or for guidance on safe usage.

In This Article

The Link Between Magnesium and Headaches

Magnesium is an essential mineral that plays a crucial role in regulating nerve function, relaxing muscles, and controlling blood vessel tone. For individuals with a magnesium deficiency, these processes can become dysregulated, contributing to headaches and migraines. Low magnesium levels can increase nerve excitability and cause blood vessels in the brain to constrict, both of which are believed to be triggers for migraine attacks.

Unlike traditional pain relievers, magnesium works by addressing potential underlying causes rather than just masking symptoms. Supplementation is typically used as a preventive measure, built up over several months to achieve its full effect, rather than as an acute treatment for a headache already in progress. While a magnesium-rich diet is beneficial, supplements are often necessary to reach therapeutic levels recommended for migraine prevention.

Comparing Different Forms of Magnesium for Headache Relief

When choosing a magnesium supplement for headache relief, bioavailability (how well the body absorbs and uses the mineral) and potential side effects are the most important factors. Different forms of magnesium are bound to different substances, which influences these characteristics. Here is a breakdown of the most common types:

  • Magnesium Glycinate: This chelated form of magnesium is bound to the amino acid glycine. Glycinate is known for its high bioavailability and is gentle on the digestive system, making it a preferred choice for many seeking headache relief without the risk of stomach upset. The calming effect of glycine can also help with associated anxiety and sleep issues.
  • Magnesium Oxide: Although it is a common and inexpensive form, magnesium oxide has a lower absorption rate compared to other types. Its primary use is often as a laxative due to its strong stool-softening properties, and it may not be the most effective for raising systemic magnesium levels. However, some clinical trials have used magnesium oxide for migraine prevention with positive results.
  • Magnesium Citrate: This form is bound to citric acid and has high bioavailability. It is easily dissolved and absorbed by the body, but it also has a laxative effect. This can be beneficial for those who also experience constipation, but it may cause gastrointestinal discomfort in others.
  • Magnesium L-Threonate: One of the newer forms on the market, L-threonate is noted for its ability to penetrate the blood-brain barrier effectively. This makes it particularly promising for directly impacting neurological function and is studied for improving cognitive function, though it is often more expensive.

How Magnesium Works to Get Rid of Headaches

Magnesium's effectiveness in preventing and reducing headaches is rooted in several physiological mechanisms:

  • Neurotransmitter Regulation: Magnesium helps control neurotransmitters like serotonin, which can play a significant role in migraine attacks. By stabilizing nerve cells, it can reduce the neuronal excitability that can lead to headaches.
  • Vasodilation and Blood Flow: As a natural calcium channel blocker, magnesium helps to relax and dilate blood vessels. This can counteract the vasoconstriction (narrowing of blood vessels) and vasodilation (widening) cycle that is associated with migraines, thereby improving blood flow to the brain.
  • Anti-inflammatory Effects: Magnesium possesses anti-inflammatory properties that can help reduce the inflammatory response involved in migraine attacks. Chronic inflammation is a known contributor to headache disorders.
  • Preventing Cortical Spreading Depression (CSD): CSD is the wave of electrical activity across the brain that is thought to be responsible for the aura experienced during migraines. Magnesium has been shown to block CSD by regulating glutamatergic neurotransmission, which plays a key role in pain transmission.

Choosing the Right Magnesium for You

Determining the best form of magnesium requires considering your individual health goals and tolerability. For most people, a highly bioavailable form with minimal side effects is ideal for long-term prevention. Here is a table to help compare your options:

Feature Magnesium Glycinate Magnesium Oxide Magnesium Citrate Magnesium L-Threonate
Bioavailability High Low High Very High (Brain-Specific)
Side Effects Gentle on stomach; may cause mild digestive issues Strong laxative effect; can cause diarrhea and stomach upset Laxative effect; can cause diarrhea Generally low digestive side effects
Best For Overall headache prevention, anxiety, and improving sleep Inexpensive option; constipation relief alongside migraine prevention Fast-absorbing option; constipation relief is also desired Targeting brain function and memory; potentially more effective for aura
Cost Mid to High Low Mid High

The Importance of Consistency and Usage

For those considering magnesium for headache and migraine prevention, consistency is essential. The effects of oral supplementation are not immediate and require a progressive buildup in the body over several weeks to months. It is often recommended to start with a lower amount and gradually increase it under the guidance of a healthcare professional.

Conclusion

While no single form of magnesium works universally for everyone, research confirms its effectiveness in migraine prevention for many individuals, particularly those with a deficiency. Magnesium glycinate is often a top recommendation due to its high bioavailability and gentleness on the stomach, making it suitable for long-term use. Other options like magnesium oxide and citrate may be better suited for those who also need help with constipation. For those targeting neurological function more directly, magnesium L-threonate is an option worth exploring. The key to successful prevention lies in choosing the right form for your body, maintaining a consistent daily intake, and discussing your regimen with a healthcare provider. While not a cure-all, magnesium represents a safe, inexpensive, and well-tolerated addition to a headache management plan.

For more detailed clinical information on magnesium's role in headache disorders, consult the American Migraine Foundation resource library.

Disclaimer: This information is for general knowledge and should not be taken as medical advice. Consult with a healthcare professional before starting any new supplement regimen.

Frequently Asked Questions

Magnesium glycinate is frequently recommended for migraine prevention due to its high bioavailability and gentle effect on the digestive system, making it easier to tolerate long-term without causing stomach upset.

Oral magnesium is most effective for prevention and is not recommended as an acute treatment for a headache that has already started. For acute relief, magnesium sulfate administered intravenously by a doctor may be effective, especially for migraines with aura.

It can take several weeks or even months of consistent, daily supplementation before you notice a significant reduction in the frequency and severity of headaches. Regular buildup in the body is required for its preventive effects.

Magnesium oxide has been used in some clinical trials for migraine prevention and can be a low-cost option. However, it has lower bioavailability and a stronger laxative effect than forms like glycinate, which may cause digestive issues.

The most common side effect of oral magnesium supplements is diarrhea and other gastrointestinal distress, especially with higher amounts or with forms like oxide and citrate. This is often related to the amount taken and can be managed by adjusting the usage or switching to a gentler form.

Foods high in magnesium include leafy green vegetables like spinach, nuts, seeds, whole grains, and dark chocolate. Incorporating these into your diet can help support your overall magnesium levels.

Magnesium supplements are generally considered safe for long-term daily use for headache prevention, but it is important to discuss this with your healthcare provider to ensure it is appropriate for you, especially if you have existing health conditions.

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.