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Who Should Not Take Ashitaba? A Comprehensive Guide to Safety

4 min read

While often praised as a health-boosting superfood, ashitaba is not suitable for everyone. A traditional Japanese herb, it is known for its regenerative properties and chalcone compounds, but certain individuals must exercise caution or avoid it entirely due to potential side effects and interactions.

Quick Summary

This guide details the specific medical conditions and circumstances under which ashitaba should be avoided, such as pregnancy, breastfeeding, and interactions with certain medications. It also explains the potential side effects and why caution is necessary for these groups.

Key Points

  • Blood Thinner Users: Ashitaba has antithrombotic properties, which can dangerously enhance the effects of blood-thinning medication.

  • Bleeding Disorder Patients: Individuals with conditions that affect blood clotting should avoid ashitaba due to an increased risk of bleeding.

  • Pregnant or Breastfeeding Women: There is insufficient safety data for ashitaba during pregnancy and lactation, so avoidance is strongly recommended.

  • Diabetics on Medication: Ashitaba can lower blood sugar, which could lead to hypoglycemia when combined with diabetes drugs.

  • Liver Condition Patients: The herb's metabolism by the liver can interfere with prescription medications and may pose a risk to those with liver impairment.

  • Individuals with Allergies: Those with a known hypersensitivity to plants in the Apiaceae family (like celery) should exercise caution.

  • Those with Sensitive Stomachs: Some users report gastrointestinal discomfort or upset stomach after taking ashitaba.

  • Pre-Surgery Patients: Due to its blood-thinning effects, ashitaba should be stopped prior to any surgical procedure.

In This Article

Who Should Not Take Ashitaba?

Ashitaba (Angelica keiskei) is a plant native to Japan, revered for centuries as a folk remedy and health-promoting vegetable. It is rich in vitamins, minerals, and unique compounds called chalcones. While generally considered safe for healthy individuals, there are several key groups who should either avoid ashitaba or consult with a healthcare provider before use due to potential contraindications and risks.

1. Individuals on Blood Thinners or with Bleeding Disorders

One of the most significant contraindications for ashitaba is its potential interaction with blood-thinning medications, also known as anticoagulants. Research indicates that certain chalcones found in ashitaba have antithrombotic properties, meaning they can inhibit platelet aggregation and reduce the risk of blood clots. While this might sound beneficial, it can be extremely dangerous when combined with prescription blood thinners like warfarin (Coumadin) or aspirin, as it can increase the risk of bleeding or bruising. For this reason, anyone with a pre-existing bleeding disorder or who is scheduled for surgery should also avoid ashitaba supplements.

2. Pregnant and Breastfeeding Women

Health experts and herbalists strongly advise against the oral consumption of ashitaba during pregnancy and breastfeeding. The primary reason for this caution is the lack of sufficient reliable scientific information and clinical studies on its effects on fetal development or infants. Since the potential risks are not yet fully understood, avoiding ashitaba is the safest approach for both the mother and the baby. This precautionary principle is standard for many herbal supplements where safety data is incomplete.

3. People with Diabetes on Medication

Ashitaba has been shown to have anti-diabetic properties, including the ability to lower blood glucose levels and enhance insulin sensitivity. While promising for diabetes management, this effect can be problematic for individuals already taking diabetes medications, such as insulin or oral hypoglycemic drugs. Combining ashitaba with these prescriptions could cause an additive effect, potentially leading to hypoglycemia (dangerously low blood sugar). Close medical supervision is essential before incorporating ashitaba into the diet of anyone managing diabetes.

4. Individuals with Liver Conditions

Ashitaba contains compounds that are metabolized by the liver, specifically through cytochrome P450 enzymes. This process is critical for breaking down many prescription drugs. For people with existing liver impairment, taking ashitaba could slow down this metabolism, increasing the effects and potential side effects of medications processed by the liver. In some animal studies, high doses of ashitaba have even been flagged with a black box warning related to potential liver harm, emphasizing the need for caution.

5. Those with Hypersensitivity to Apiaceae Family Plants

Ashitaba belongs to the Apiaceae family, which also includes common vegetables like celery, parsley, and carrots. Individuals who have a known allergy or hypersensitivity to any plants in this family should be cautious about taking ashitaba, as they may experience an allergic reaction. Symptoms could range from a mild rash to more severe allergic responses.

6. People with Gastrointestinal Discomfort

While ashitaba is sometimes used to aid digestive health, some individuals report experiencing gastrointestinal discomfort as a side effect. This can include symptoms like upset stomach or indigestion. If you have a sensitive stomach or a history of digestive issues, it is wise to start with a very small dose or avoid it altogether.

Comparison: Ashitaba with vs. without Medical Supervision

Feature Taking Ashitaba with Medical Supervision Taking Ashitaba without Medical Supervision
Safety for at-risk groups Significantly safer; a healthcare provider can monitor for drug interactions, side effects, and adjust dosage accordingly. High risk, especially for those on blood thinners, diabetic medication, or with liver issues; potential for serious adverse effects.
Usage during pregnancy/breastfeeding A doctor's consultation would reinforce avoidance due to insufficient safety data. Avoidance is crucial; taking without consultation can lead to unknown risks to the fetus or infant.
Personalized dosage Dosage can be tailored based on your health status, existing medications, and desired outcome. Dosage is often generic and may not be suitable for your specific health profile, increasing risk.
Side effect management Any adverse effects can be discussed with and managed by a professional immediately. Individuals may not recognize side effects or know how to manage them, potentially leading to complications.
Benefit assessment A doctor can help weigh the potential benefits against the risks for your specific situation. Benefits are often taken at face value without considering individual health risks.

Summary of Cautions

For most healthy adults, consuming ashitaba in moderation may offer potential health benefits. However, the available scientific research is still limited, especially concerning long-term use and high-dosage therapeutic applications. The lack of comprehensive safety data means that prudence is necessary for certain groups. The interaction with medications and the potential effects on conditions like bleeding disorders and liver function are significant concerns that should not be overlooked. The absolute recommendation for avoidance in pregnant and breastfeeding women is a standard and critical safety precaution.

Conclusion

While the folklore and potential health benefits of ashitaba are compelling, a responsible approach to supplementation requires an understanding of its contraindications. The crucial takeaway is that anyone with pre-existing medical conditions, particularly those on blood thinners or diabetes medication, and all pregnant or breastfeeding women should avoid ashitaba. For these individuals, a conversation with a healthcare provider is not merely a suggestion but a necessary step to ensure safety and prevent potentially serious health complications. The limited research available means that those in high-risk categories should always err on the side of caution.

Disclaimer

This article is for informational purposes only and is not medical advice. Always consult with a qualified healthcare professional before starting any new dietary supplement, especially if you have pre-existing health conditions or are taking medications.

Authoritative Source

The National Institutes of Health (NIH) is a leading source for research on dietary supplements, including traditional herbs.

Frequently Asked Questions

No, it is not recommended to take ashitaba if you are on blood thinners. Ashitaba possesses antithrombotic properties that can enhance the effects of these medications, significantly increasing the risk of dangerous bleeding or bruising.

No, pregnant and breastfeeding women should avoid taking ashitaba. There is not enough reliable scientific information to determine its safety for the developing fetus or infant, making avoidance the safest option.

For individuals with diabetes, ashitaba can lower blood glucose levels. If you are already taking medication for diabetes, combining it with ashitaba could lead to hypoglycemia (low blood sugar), so it should only be used under strict medical supervision.

Yes, ashitaba may interact with medications processed by the liver's cytochrome P450 enzymes. This can increase the effects and potential side effects of those drugs. Always consult a doctor if you are on any prescription medication.

While often well-tolerated, some users may experience side effects such as gastrointestinal discomfort, including an upset stomach. Individuals with known allergies to related plants in the carrot family might also experience a reaction.

Yes, due to its potential antithrombotic (blood-thinning) effects, it is crucial to stop taking ashitaba well in advance of any scheduled surgery. This helps prevent excessive bleeding during and after the procedure.

Those with liver or kidney impairment should proceed with caution and consult a healthcare professional. The herb is metabolized by the liver, and high doses in some animal studies have raised concerns about potential hepatic risks.

Like many traditional herbal supplements, the therapeutic use of ashitaba has not been extensively studied in large-scale human clinical trials. Most evidence comes from traditional use, animal studies, or in vitro research, leading to a gap in comprehensive safety data.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.