Skip to content

Are Steviol Glycosides Good or Bad for You?

4 min read

Over 50 countries have approved the use of high-purity steviol glycosides in food products, reflecting widespread regulatory acceptance. This has led many to question the definitive safety and health implications of steviol glycosides as a sugar substitute.

Quick Summary

This article explores the health effects of steviol glycosides, detailing their potential benefits for blood sugar management and weight control, while also addressing possible side effects and safety considerations.

Key Points

  • Approved Purity Matters: Only highly purified steviol glycoside extracts (95%+ purity) are considered safe for consumption by major regulatory bodies like the FDA, not raw leaves or crude extracts.

  • Zero Calorie and Blood Sugar Friendly: As a non-nutritive sweetener, purified steviol glycosides do not raise blood sugar or insulin levels, making them suitable for people with diabetes.

  • Aids in Weight Management: By replacing caloric sugar, steviol glycosides can assist with weight control by helping to reduce overall calorie intake.

  • Watch for Additives: Many commercial stevia products contain other ingredients like sugar alcohols (erythritol) or sugars (maltodextrin) that can cause digestive issues or affect blood sugar.

  • Potential for Medication Interactions: Due to effects on blood sugar and blood pressure, individuals on related medications should consult a doctor before incorporating steviol glycosides.

  • Mixed Findings on Gut Health: Some research suggests potential effects on the gut microbiome, but results are mixed and more studies are needed to determine the long-term impact.

  • Safe in Moderation: When consumed within the acceptable daily intake (ADI), purified steviol glycosides are considered safe for the general population, including children and pregnant women.

In This Article

What are Steviol Glycosides?

Steviol glycosides are the naturally occurring, intensely sweet compounds found in the leaves of the Stevia rebaudiana (Bertoni) plant. Native to South America, the stevia plant has been used for centuries by indigenous populations to sweeten food and drink. The sweetening power of these compounds is significant, with some being up to 400 times sweeter than table sugar (sucrose). After a processing and purification phase, these compounds become the zero-calorie sweetener known as stevia extract that is sold commercially.

The Purification Process

It is crucial to differentiate between raw stevia leaves and the highly purified steviol glycoside extracts found in approved food products. Regulatory bodies like the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA) only recognize the high-purity extracts (typically 95% or higher steviol glycosides) as Generally Recognized As Safe (GRAS). Raw stevia leaf and crude extracts are not approved for use in foods due to insufficient safety data.

Potential Health Benefits of Steviol Glycosides

For many, the main appeal of steviol glycosides is their zero-calorie nature, making them a useful tool for weight management and sugar reduction. However, research also points to other potential health benefits:

  • Blood Sugar Management: Numerous studies suggest that replacing sugar with steviol glycosides can help manage blood sugar levels in individuals with diabetes. Since the body does not metabolize them for energy, they do not cause a spike in blood glucose or insulin levels. A 2018 study even found a decrease in blood glucose levels in participants with chronic kidney disease who consumed stevia supplements.
  • Weight Control: By providing a sweet taste without the calories of sugar, steviol glycosides can help reduce overall calorie intake. This can be a beneficial strategy for people looking to lose or maintain weight. Randomized controlled trials have shown that sweeteners like stevia can assist with weight loss goals.
  • Dental Health: Unlike sugar, steviol glycosides are not fermented by oral bacteria, meaning they do not contribute to tooth decay or cavities. This makes them a great option for promoting better dental hygiene.
  • Blood Pressure: Some research indicates that steviol glycosides may have a positive effect on blood pressure by acting as a vasodilator, widening blood vessels. However, this is not a universally confirmed effect, and individuals with low blood pressure should be cautious.
  • Antioxidant and Anti-inflammatory Properties: The Stevia rebaudiana plant contains antioxidants like kaempferol and quercetin. While the purification process may reduce these, some evidence suggests steviol glycosides still offer antioxidant and anti-inflammatory benefits.

Potential Risks and Side Effects

Despite the benefits, there are important considerations and potential drawbacks associated with steviol glycoside consumption:

  • Digestive Issues: Some stevia products are blended with sugar alcohols, such as erythritol, to improve taste and bulk. These can cause gastrointestinal distress, including bloating, gas, and nausea in sensitive individuals.
  • Altered Gut Microbiome: While inconclusive, some studies suggest that zero-calorie sweeteners like steviol glycosides could potentially interfere with the balance of beneficial gut bacteria. The long-term effects of this are not yet fully understood.
  • Medication Interactions: Steviol glycosides can lower both blood sugar and blood pressure, potentially causing interactions with medications prescribed for diabetes and hypertension. It is important to consult a healthcare provider if you take these medications.
  • Hidden Additives: Many commercial stevia products are not 100% pure steviol glycosides. Always check the label for added sugars (like maltodextrin and dextrose) or other sweeteners, which can add calories or affect blood sugar levels.
  • Aftertaste: Some people find that stevia has a distinct, sometimes bitter, licorice-like aftertaste, especially in less refined products. This can be a deterrent for some consumers.

Comparison: Steviol Glycosides vs. Table Sugar (Sucrose)

Feature Steviol Glycosides Table Sugar (Sucrose)
Source Natural plant extract (Stevia rebaudiana) Naturally occurring in plants (sugar cane, beets)
Calories Zero Approximately 16 calories per teaspoon
Glycemic Impact No effect on blood sugar or insulin levels Rapidly raises blood sugar and insulin levels
Sweetness 200-400 times sweeter than sucrose Standard unit of comparison for sweetness
Dental Effects Non-cariogenic; does not cause tooth decay Major contributor to cavities and tooth decay
Weight Management Can aid in weight control by reducing calorie intake Excessive consumption linked to weight gain and obesity
Common Forms Highly purified extracts (Reb-A, Reb-M) Refined crystals
Potential Issues Aftertaste, potential gut microbiome effects Weight gain, diabetes, dental problems

Conclusion

In conclusion, the question of whether steviol glycosides are 'good' or 'bad' for you largely depends on context and product form. High-purity steviol glycoside extracts are approved by regulatory bodies worldwide, including the FDA, and are generally considered a safe, zero-calorie alternative to sugar. They can be a beneficial tool for managing blood sugar, controlling weight, and protecting dental health. However, the key is moderation and careful product selection. Blended stevia products containing other additives, such as sugar alcohols or sugars, can negate some of the health benefits and may cause side effects. Furthermore, individuals on certain medications for blood pressure or diabetes should consult a doctor due to potential interactions. While raw stevia leaves are not approved for food use and lack safety data, purified steviol glycosides offer a sweet taste without the caloric burden of sugar, representing a smart choice for many seeking to reduce their sugar intake. National Institutes of Health (NIH) on Steviol Glycosides

Frequently Asked Questions

Older concerns about stevia's effect on kidneys have largely been disproven by more recent studies. In fact, some research suggests stevia may have a protective effect on kidneys, but further research is needed.

Pure steviol glycosides are not typically associated with digestive problems. However, some commercial stevia products contain sugar alcohols like erythritol, which can cause bloating, gas, and nausea in some individuals.

Yes, highly purified steviol glycosides are generally considered safe for people with diabetes. They are zero-calorie and do not raise blood glucose or insulin levels, making them a good sugar alternative.

No, the FDA has not approved raw stevia leaves or crude extracts for use in food due to a lack of sufficient safety data. Only highly purified steviol glycoside extracts (95%+) have GRAS status.

By providing a sweet taste without calories, steviol glycosides can help reduce overall calorie intake when used as a sugar substitute, which can contribute to weight loss.

The acceptable daily intake (ADI) for steviol glycosides is set at 4 mg per kilogram of body weight per day (as steviol equivalents) by regulatory bodies like the WHO and EFSA.

Yes, steviol glycosides can potentially interact with medications for diabetes and high blood pressure, as they can lower both blood sugar and blood pressure levels. Consult a doctor if you are on these medications.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.