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Are there any downsides to eating nutritional yeast? A comprehensive guide

4 min read

While lauded for its savory, cheesy flavor and B-vitamin content, studies suggest there are specific health conditions and sensitivities that warrant caution when consuming this popular food additive. So, are there any downsides to eating nutritional yeast? For some individuals, the answer is yes, depending on their health status and how much they consume.

Quick Summary

Nutritional yeast can cause digestive issues, trigger migraines in sensitive individuals, or lead to niacin flushing if consumed in large amounts. Certain medical conditions and medications require consulting a doctor before use.

Key Points

  • Digestive issues: Introduce nutritional yeast gradually to prevent bloating, gas, or cramping caused by its high fiber content.

  • Migraine trigger: The naturally occurring tyramine in nutritional yeast can trigger headaches or migraines in sensitive individuals.

  • Niacin flush: Fortified varieties with high levels of niacin can cause temporary skin flushing, tingling, or itching.

  • IBD flare-ups: Individuals with Inflammatory Bowel Disease like Crohn's may experience worsened symptoms after consuming nutritional yeast.

  • Medication interactions: Nutritional yeast is contraindicated for those taking MAOI antidepressants and requires caution with diabetes medication due to tyramine.

  • Fortification inconsistency: Relying on nutritional yeast as the sole source of B12 can be risky, as fortification levels can be unreliable.

  • Caution for specific conditions: People with glaucoma, high blood pressure, gout, and kidney issues should exercise caution or avoid it.

In This Article

What is Nutritional Yeast?

Nutritional yeast, often called "nooch," is a deactivated strain of Saccharomyces cerevisiae, the same type of yeast used in baking and brewing. Unlike its active counterparts, nutritional yeast is heat-treated to deactivate it, meaning it will not cause fermentation or act as a leavening agent. It is sold as a yellow powder or flakes and is beloved in plant-based diets for its nutty, cheesy, and savory umami flavor. While it's celebrated for being a good source of fiber, protein, and B vitamins (especially B12 in fortified varieties), it's important to understand that it's not without potential drawbacks for some people.

Potential Digestive Issues

One of the most common complaints about nutritional yeast, particularly when new to the diet or consumed in large quantities, is digestive upset. This is largely due to its high fiber content. A two-tablespoon serving can provide a significant portion of your daily recommended fiber intake. For individuals not used to a high-fiber diet, a rapid increase can lead to:

  • Bloating
  • Gas
  • Abdominal cramping
  • Diarrhea

To avoid these issues, experts recommend introducing nutritional yeast slowly and in small amounts, gradually increasing your intake as your body adjusts. Ensuring you drink plenty of water is also crucial when increasing dietary fiber.

Can Trigger Headaches and Migraines

Nutritional yeast contains tyramine, a naturally occurring amino acid that can affect blood pressure. While most people can consume tyramine-containing foods without issue, certain individuals, particularly those prone to migraines, may find that it acts as a trigger. The mechanism is still being studied, but it is believed that tyramine may cause a release of hormones that increase blood pressure, potentially leading to a migraine attack.

Risks Associated with High Niacin Content

Many nutritional yeast products are fortified with vitamins, including niacin (vitamin B3), to boost their nutritional profile. However, some fortified brands contain very high levels of niacin, sometimes exceeding the tolerable upper intake level in a single serving. Consuming excessively high doses of niacin can lead to a condition known as "niacin flushing," which involves:

  • A flush of red on the skin, especially on the face, chest, and arms
  • A burning, tingling, or itching sensation
  • Headaches and dizziness

While niacin flushing is generally harmless and temporary, it can be uncomfortable. It's important to check the nutrition facts, especially if you also take other supplements containing B vitamins.

Exacerbates Symptoms for Individuals with IBD

For some people with Inflammatory Bowel Disease (IBD), such as Crohn's disease, consuming nutritional yeast can worsen symptoms. Studies suggest that the yeast Saccharomyces cerevisiae can trigger an immune response in some IBD patients, potentially leading to a flare-up of their condition. The specific role and mechanism are still not fully understood, but individuals with IBD should be cautious and consult their doctor before adding nutritional yeast to their diet.

Medication Interactions

The tyramine found in nutritional yeast can interact dangerously with certain medications, primarily an older class of antidepressants known as monoamine oxidase inhibitors (MAOIs). This interaction can cause a sharp and dangerous spike in blood pressure, potentially leading to severe headaches. Furthermore, nutritional yeast may not be recommended for individuals on medication for diabetes, and some sources suggest interactions with certain antifungal drugs. Anyone taking prescription medication, especially MAOIs, should speak with a healthcare provider before consuming nutritional yeast.

Fortification Levels are Inconsistent

While fortified nutritional yeast is a popular source of vitamin B12 for vegans, it is not a consistently reliable one. An independent group that tested various brands of nutritional yeast found that the nutrient levels listed on the labels were not always accurate. For individuals with a diagnosed vitamin B12 deficiency, relying on nutritional yeast alone may not be sufficient, and a standardized supplement may be more appropriate.

Comparison of Normal Use vs. Potential Risks

Feature Normal Consumption (for most people) Potential Risks (for some individuals)
Digestive System A great source of fiber that supports gut health. Can cause bloating, gas, or diarrhea if introduced too quickly due to high fiber content.
Flavor Adds a rich, umami, and cheesy flavor to dishes. No inherent risk, but individuals with MSG sensitivity should be aware of glutamate content.
Migraines Safe for the vast majority of people. Tyramine content can trigger headaches or migraines in susceptible individuals.
Niacin Provides a good source of B vitamins, including B3. Excessive amounts from fortified brands can cause temporary niacin flush (burning, itching).
IBD Can support immune function and gut health via beta-glucans. May worsen symptoms of Inflammatory Bowel Disease like Crohn's disease.
Medication Generally safe. Tyramine interacts dangerously with MAOI antidepressants, and caution is advised with diabetes medication.

Who Should Be Cautious?

While a fantastic food for many, certain people should be cautious or avoid nutritional yeast altogether. This includes:

  • Individuals with Inflammatory Bowel Disease (IBD) or Irritable Bowel Syndrome (IBS).
  • Those who experience migraines or tyramine sensitivity.
  • People taking MAOI medications.
  • Individuals with a diagnosed yeast allergy or sensitivity.
  • People with a history of glaucoma, high blood pressure, gout, or kidney stones should consult a doctor.

Conclusion

Nutritional yeast is a versatile and nutrient-dense condiment that offers numerous benefits for most people, especially those following vegan or vegetarian diets. However, it is not a one-size-fits-all superfood. The potential for digestive discomfort, migraine triggers, medication interactions, and exacerbated IBD symptoms highlights the need for a cautious approach, particularly for those with pre-existing health conditions or sensitivities. Introducing it slowly and in moderation is key to mitigating potential side effects. As with any significant dietary change, it is always wise to consult with a healthcare professional, especially if you have concerns or underlying health issues. By being aware of the potential downsides, you can enjoy nutritional yeast responsibly and ensure it aligns with your overall health goals. For more in-depth information, resources from reliable health organizations like WebMD provide further context.

Frequently Asked Questions

Yes, nutritional yeast can cause an upset stomach, especially when introduced too quickly or in large amounts. This is due to its high fiber content, which can lead to bloating, gas, cramping, or diarrhea if your digestive system isn't used to it.

While rare, it is possible to have an intolerance or allergy to yeast, including the Saccharomyces cerevisiae strain used in nutritional yeast. Symptoms would be similar to other food sensitivities and reactions.

Yes, nutritional yeast can interact with medications. The tyramine it contains can cause a dangerous blood pressure spike in individuals taking Monoamine Oxidase Inhibitors (MAOIs). Caution is also advised for people on diabetes or antifungal medications.

Nutritional yeast may not be safe for people with Inflammatory Bowel Disease (IBD), such as Crohn's disease. The yeast can potentially trigger an immune response and worsen symptoms, so it's best for individuals with IBD to consult their doctor before consuming it.

A hot or flushed feeling, known as niacin flushing, can occur if you consume a very high amount of niacin (vitamin B3) from fortified nutritional yeast. It is a temporary, though sometimes uncomfortable, side effect.

Yes, nutritional yeast naturally contains tyramine. For most people, this is not an issue, but for individuals who are sensitive to it or prone to migraines, it can act as a trigger.

Nutritional yeast contains purines, which can exacerbate gout or increase the likelihood of kidney stones in susceptible individuals. Those with a history of these conditions should consult a doctor.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.