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Beyond the Basics: What should I take besides a multivitamin?

4 min read

According to a 2017 report, global sales of probiotic supplements reached $3.7 billion in 2016, a testament to the fact that many people seek to augment their nutrition beyond basic multivitamins. For those looking to optimize their health, understanding what should I take besides a multivitamin is a crucial next step.

Quick Summary

Optimizing nutrition often requires more than a daily multivitamin. Key supplements to consider include Vitamin D for immune and bone health, Omega-3 fatty acids for heart and brain function, and Magnesium for relaxation and energy. Probiotics and Coenzyme Q10 offer additional targeted benefits for gut and cardiovascular health.

Key Points

  • Start with the basics: While a multivitamin is a good foundation, many people need targeted supplements like Vitamin D, Omega-3s, and Magnesium to meet their specific needs.

  • Boost bone health with a duo: Pair Vitamin D with Magnesium and Vitamin K2 for optimal calcium absorption and bone density.

  • Support your heart and brain: Omega-3 fatty acids (EPA and DHA) from fish oil or algae are crucial for cardiovascular and cognitive function.

  • Improve sleep and stress response: Magnesium is a powerful mineral that promotes relaxation, aids sleep, and supports muscle function.

  • Enhance gut flora: Probiotics can help restore the balance of beneficial bacteria in your gut, which impacts immunity and digestion.

  • Consider specific health goals: Supplements like Coenzyme Q10 can support heart health, especially for older adults or those on statins.

In This Article

A daily multivitamin is a great nutritional starting point for many, but it is rarely a comprehensive solution for optimal health. Many people, especially those with certain dietary restrictions, age-related changes, or health goals, can benefit from targeted supplementation. By focusing on specific nutrients, you can address potential deficiencies and enhance your well-being. This guide explores key supplements to consider adding to your routine, alongside dietary sources to complement your intake.

The Power Trio: Vitamin D, Omega-3s, and Magnesium

Vitamin D: The Sunshine Vitamin

Often called the 'sunshine vitamin,' Vitamin D is crucial for bone strength because it helps your body absorb calcium. A significant portion of the population is deficient, especially during darker months or with limited sun exposure. Vitamin D also plays a vital role in immune function, mood regulation, and reducing inflammation.

  • Dietary Sources: Few foods naturally contain high levels, but options include oily fish (salmon, sardines), fortified foods (milk, cereal), and egg yolks.
  • Supplementation: Many health experts recommend a Vitamin D3 supplement, often taken with Vitamin K2 to improve calcium regulation and direct it to the bones.

Omega-3 Fatty Acids: For Your Heart and Mind

Omega-3s, particularly EPA and DHA found in fatty fish, are essential polyunsaturated fats that support heart, brain, and joint health. The body can convert plant-based ALA into EPA and DHA, but at a very low rate, making direct dietary intake or supplementation of EPA and DHA important.

  • Dietary Sources: Excellent sources include fatty fish like salmon, mackerel, and sardines. Plant-based sources of ALA include flaxseed, chia seeds, and walnuts.
  • Supplementation: High-quality, third-party tested fish oil or algal oil (for vegans) can provide the recommended 500–1,000 mg of EPA+DHA daily.

Magnesium: The Relaxation Mineral

Magnesium is involved in over 300 enzymatic reactions in the body, influencing everything from energy production and muscle function to sleep and relaxation. Chronic stress, certain medications, and poor diet can all contribute to low magnesium levels.

  • Dietary Sources: Magnesium-rich foods include leafy greens, nuts, seeds, and whole grains.
  • Supplementation: Different forms of magnesium have different benefits. Magnesium glycinate is often recommended for sleep and stress, while magnesium citrate can help with digestion.

Specialized Supplements for Targeted Goals

Probiotics for Gut Health

The gut microbiome is a complex ecosystem of microbes that influences digestion, immunity, and even mood via the gut-brain axis. An imbalance can lead to various health issues. Probiotics introduce beneficial bacteria to help rebalance the gut's environment.

  • Dietary Sources: Fermented foods like yogurt, kefir, sauerkraut, kimchi, and kombucha are natural probiotic sources.
  • Supplementation: Look for products with specific, proven strains like Lactobacillus and Bifidobacterium, and check that they contain 'live and active cultures'.

Coenzyme Q10 for Cardiovascular Support

Coenzyme Q10 (CoQ10) is a potent antioxidant that supports cellular energy production, particularly in high-energy organs like the heart. Levels naturally decline with age and can also be affected by statin use.

  • Dietary Sources: Organ meats, fatty fish, nuts, and some oils contain CoQ10, but typically in lower concentrations than supplements.
  • Supplementation: Taking a CoQ10 supplement, especially in the more bioavailable ubiquinol form, can help maintain optimal levels, potentially benefiting heart health.

Food vs. Supplements: Making the Right Choice

Ideally, the majority of your nutrients should come from a varied and healthy diet. Foods offer a complete package of vitamins, minerals, fiber, and other beneficial compounds that work synergistically. However, in cases of specific deficiencies, malabsorption, or higher-than-average needs, supplementation can be a powerful tool to fill the gaps. Before adding supplements, it is always best to consult with a healthcare provider to ensure you choose the correct form and dosage for your individual needs.

Comparing Key Supplements

Supplement Primary Benefits Common Food Sources Considerations Recommended Pairings
Vitamin D Bone health, immune support, mood regulation Oily fish, fortified dairy, eggs Limited sunlight exposure is a risk factor Magnesium, Vitamin K2
Omega-3s Heart, brain, and joint function Fatty fish, flaxseed, walnuts, chia seeds Algal oil is a vegan alternative to fish oil Vitamin D
Magnesium Relaxation, sleep, muscle function, energy Leafy greens, nuts, seeds, whole grains Deficiency is common, especially with stress Vitamin D
Probiotics Gut health, immune function, digestion Yogurt, kefir, sauerkraut, kombucha Look for products with 'live and active cultures' Prebiotic fiber to feed good bacteria
Coenzyme Q10 Heart health, antioxidant protection, energy Organ meats, fatty fish, nuts Levels decline with age and statin use Healthy fats for improved absorption

Complementing Your Diet for Optimal Health

Ultimately, supplements are meant to complement, not replace, a nutritious diet rich in whole foods. A foundation of a healthy eating pattern, combined with targeted supplementation based on individual needs and health goals, is the most effective approach. For example, a vegetarian or vegan might need to focus on iron and Vitamin B12, often found in animal products. Older adults may face challenges with nutrient absorption and require increased intake of certain vitamins and minerals. Consulting a healthcare provider or a registered dietitian is the best way to tailor a plan to your unique requirements.


The information in this article is for informational purposes only and does not constitute medical advice. Consult a healthcare professional before starting any new supplement.

Frequently Asked Questions

Beyond bone health, Vitamin D plays a significant role in immune system function, regulating mood and energy, and reducing inflammation.

Yes. The body converts plant-based ALA to EPA and DHA at a very low rate, so vegans and vegetarians should seek supplements like algal oil or ensure high intake of ALA sources like flaxseed.

Magnesium glycinate is often recommended for its calming properties that aid relaxation and sleep. Magnesium L-threonate also shows promise for cognitive benefits and sleep.

The best time to take a probiotic depends on the product, but many can be taken with food. Fermented foods offer a natural, less concentrated source of beneficial bacteria.

Older adults and individuals taking statin medications may benefit from CoQ10 supplementation, as both age and these medications can deplete the body's natural levels.

It is often difficult to get all necessary nutrients from diet alone due to factors like food processing, nutrient absorption issues, and specific dietary patterns. Supplements can help fill these gaps, but should not replace a healthy diet.

Yes. For example, high doses of Vitamin E can interfere with Vitamin K, and some supplements can impact medication effectiveness. It is essential to consult a healthcare provider before starting any new supplement.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.