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Can you take magnesium and calcium together at night?

4 min read

According to a study from the Coronary Artery Risk Development in Young Adults (CARDIA), higher magnesium intake is associated with better sleep quality and duration. This raises the question of whether you can take magnesium and calcium together at night to enhance these sleep benefits.

Quick Summary

While generally safe, taking magnesium and calcium supplements separately is often recommended to maximize absorption due to competitive pathways. Magnesium is best taken at night for relaxation, while calcium is often better earlier in the day for peak efficacy.

Key Points

  • Separate for Absorption: Taking magnesium and calcium at different times of day is recommended to prevent absorption competition, especially at high doses.

  • Magnesium for Night: For sleep benefits, take magnesium about an hour before bed to promote relaxation and calm the nervous system.

  • Calcium Timing: Taking calcium earlier in the day with food is often ideal, as some forms, like calcium carbonate, require stomach acid for best absorption.

  • Choose the Right Forms: Opt for magnesium glycinate or L-threonate for their calming effects, and be mindful of laxative effects from magnesium citrate before bed.

  • Maintain Optimal Ratios: Be aware of the balance between the minerals, as magnesium is crucial for proper calcium utilization in the body.

  • Prioritize Diet: Incorporating mineral-rich foods like leafy greens, nuts, and dairy can naturally regulate levels and support your supplement routine.

In This Article

Understanding the Mineral Dynamic at Night

Magnesium and calcium are two vital minerals that play crucial roles in countless bodily functions, including bone health, muscle function, and nerve signaling. While they often work together, their relationship regarding absorption is complex. When taken in high doses simultaneously, these minerals compete for the same absorption pathways in the intestines, which can reduce the bioavailability of both. For this reason, and due to their different effects on the body's nighttime functions, timing and balance are key considerations for nighttime supplementation.

Why Magnesium is a Popular Nighttime Supplement

Magnesium is known for its calming properties and is often called the “relaxation mineral”.

  • Nervous System Regulation: It plays a key role in regulating neurotransmitters, particularly GABA (gamma-aminobutyric acid), which helps to quiet brain activity and promote relaxation.
  • Muscle Relaxation: It helps muscles relax, which can reduce tension and alleviate nocturnal leg cramps that might disrupt sleep.
  • Melatonin Regulation: Magnesium helps regulate melatonin, the hormone that governs the body's sleep-wake cycle.

Calcium's Role in Sleep and Its Timing Considerations

Calcium also contributes to the sleep process by helping the brain convert the amino acid tryptophan into melatonin. However, unlike magnesium's direct relaxing effect, calcium's timing is more flexible, and some evidence suggests taking it in the evening might be counterproductive or less efficient.

  • Calcium Absorption: Forms like calcium carbonate require stomach acid for optimal absorption, making it beneficial to take with food. Taking it with an earlier meal helps maximize absorption without interfering with a nighttime magnesium dose.
  • Circadian Rhythm: Taking calcium at night could theoretically align with the body's natural rhythms, but the competition with magnesium for absorption is a more pressing practical consideration.

Best Practice for Combining Supplements

For optimal absorption and to avoid competition between minerals, many experts and supplement brands suggest separating the intake of magnesium and calcium. A common approach is to take magnesium in the evening to leverage its relaxing effects for sleep, and take calcium earlier in the day, preferably with a meal. This strategy ensures that the body can absorb and utilize each mineral more efficiently.

Choosing the Right Form of Supplement

Different forms of magnesium and calcium have different absorption rates and side effects. Choosing the right one can further optimize your supplement routine.

Magnesium Forms

  • Magnesium Glycinate: Often recommended for sleep due to its high bioavailability and calming properties.
  • Magnesium L-Threonate: Known for its ability to cross the blood-brain barrier, making it effective for cognitive function and tranquility.
  • Magnesium Citrate: Can have a mild laxative effect, so it's less ideal right before bed if GI distress is a concern.

Calcium Forms

  • Calcium Carbonate: Best taken with food due to its dependence on stomach acid for absorption.
  • Calcium Citrate: Can be taken with or without food and is often more easily absorbed by individuals with less stomach acid.

Comparison of Nighttime Supplementation

Feature Magnesium for Sleep Calcium for Sleep Optimal Nighttime Routine
Primary Function Calms nervous system, relaxes muscles Assists in melatonin production Magnesium for relaxation and sleep induction.
Absorption Concern Can be inhibited by high calcium doses Less of a concern if taken separately from magnesium Take separately to maximize absorption of both minerals.
Best Timing Nighttime (1-2 hours before bed) Can be taken anytime, often recommended earlier Magnesium at night; Calcium with a meal earlier in the day.
Ideal Forms Glycinate, L-threonate Citrate (can be taken anytime), Carbonate (with food) Matching timing with the best form.

Dietary Considerations for Natural Intake

Supplementing is not the only way to balance your intake. You can also focus on foods rich in these minerals:

  • Magnesium-rich foods: Leafy greens (spinach, kale), nuts (almonds), seeds (chia, pumpkin), and dark chocolate.
  • Calcium-rich foods: Dairy products (milk, yogurt), leafy greens (kale, broccoli), and fortified foods. By incorporating these foods throughout the day, you can help regulate your mineral levels naturally and potentially reduce the need for high-dose supplements at once. If you do take supplements, always consult with a healthcare professional to determine the right dosage for your needs, as imbalances can occur.

Conclusion

Ultimately, you can take magnesium and calcium together at night, but it is not the most effective approach for maximizing absorption. Taking high doses simultaneously can cause them to compete for uptake in the body. The best strategy for most individuals is to separate the intake, taking a calming form of magnesium (like glycinate) about an hour before bed for relaxation and better sleep, while consuming calcium supplements with a meal earlier in the day to optimize its absorption. This timed approach allows your body to efficiently utilize both minerals, supporting overall health and improving your nightly rest.

For more detailed information on magnesium, consult the National Institutes of Health: Office of Dietary Supplements' fact sheet on magnesium.

Frequently Asked Questions

You can, but taking them separately is generally more effective. High doses of magnesium and calcium can compete for the same absorption pathways in the intestines, which may reduce the effectiveness of both minerals.

Magnesium is best taken in the evening, approximately one to two hours before bedtime. This timing allows the mineral's calming effects to help relax muscles and the nervous system before you try to fall asleep.

To avoid competition with magnesium for absorption, it is often recommended to take calcium with a meal earlier in the day. Certain forms, like calcium carbonate, are best absorbed with food.

For promoting relaxation and sleep, magnesium glycinate and magnesium L-threonate are often recommended. Magnesium citrate can have a laxative effect and may not be the best choice for bedtime.

Many combined supplements are formulated with specific ratios (e.g., 2:1 calcium to magnesium) to minimize absorption issues. However, for maximum efficacy, separating the intake is still the most recommended approach, especially if you take other medications that interact with these minerals.

Yes, deficiencies in either mineral can affect sleep. Low magnesium can lead to agitated sleep, while low calcium can impact the brain's ability to produce melatonin.

Excessive intake of either mineral can cause side effects. High magnesium can cause diarrhea, while high calcium can lead to constipation and other issues. It is important to stick to recommended dosages.

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.