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Do Probiotics Help When You're Already Sick?

4 min read

According to the Cochrane Library, probiotics may reduce the duration of an upper respiratory tract infection by about 1.22 days. But can these 'good bacteria' help when you're already feeling unwell? This article explores how probiotics can support your immune system during an illness and whether starting them mid-sickness is worthwhile.

Quick Summary

This article examines the efficacy of taking probiotics during illness, focusing on their mechanisms for modulating the immune system and gut microbiome. It reviews evidence for reducing the duration and severity of respiratory and gastrointestinal infections, and discusses which specific strains may be beneficial, concluding with important safety considerations.

Key Points

  • Immune Support: Probiotics can help modulate the immune system during sickness by supporting the gut-associated lymphoid tissue (GALT), where a majority of immune cells reside.

  • Reduced Symptom Severity: Research suggests that certain probiotic strains can help reduce the severity of symptoms for respiratory infections like the common cold, even when started during the illness.

  • Shorter Illness Duration: Probiotics may potentially shorten the duration of illnesses, including viral upper respiratory tract infections and infectious diarrhea.

  • Gastrointestinal Relief: For diarrhea caused by viral infections or antibiotics, specific probiotic strains can help rebalance the gut microbiome and alleviate symptoms.

  • Strain Specificity Matters: The effectiveness of probiotics is highly dependent on the specific strain, so choosing a well-researched strain or combination is crucial for desired effects.

  • Safety First: Individuals with severely compromised immune systems should consult a healthcare provider before taking probiotics.

  • Timing Can Help: While preventative use is beneficial for long-term health, starting probiotics during an illness can still offer valuable immune and gut support.

In This Article

Understanding the Gut-Immune Connection

Your gut is home to trillions of microorganisms, collectively known as the gut microbiome, and plays a crucial role in your overall health. Up to 80% of your body's immune cells reside in the gut-associated lymphoid tissue (GALT), making the gut a central hub for immune system activity. The balance of beneficial and harmful bacteria in this ecosystem directly influences how effectively your body responds to infections. When you get sick, this delicate balance can be disrupted, especially if you are taking antibiotics, which kill off beneficial bacteria along with the harmful ones. Probiotics, which are live microorganisms, help restore this balance by replenishing the population of 'good' bacteria, thereby supporting a more robust immune response.

Probiotics and Respiratory Infections

Research suggests that certain probiotic strains can help mitigate the severity and duration of upper respiratory tract infection (URTI) symptoms, even when started after the onset of illness. These benefits are attributed to probiotics' ability to modulate the immune system by stimulating both innate and adaptive immune responses. {Link: ICNS https://www.icns.es/en/news/probiotics_reduce_duration_severity_cold}.

Can You Start Probiotics During an Illness?

While preventive use is often recommended, taking a dose during illness might reduce symptoms and shorten recovery. The goal is to provide immediate immune support.

Probiotics and Gastrointestinal Illnesses

Diarrhea is a common symptom of illness, whether from a viral infection or as a side effect of antibiotics. Research shows that certain probiotic strains are particularly effective for treating infectious diarrhea, especially in children. Saccharomyces boulardii, a beneficial yeast, and specific Lactobacillus and Bifidobacterium strains have been shown to reduce the duration of diarrhea by restoring the intestinal flora. For antibiotic-associated diarrhea (AAD), probiotics can help rebalance the gut flora and shorten the duration of diarrhea once it has started.

Comparison: Probiotics When Sick vs. Healthy

Aspect Probiotics When Sick Probiotics When Healthy
Primary Goal Modulate immune response and reduce duration/severity of symptoms. Maintain gut microbiome diversity and overall wellness.
Immune Mechanism Stimulate both innate and adaptive immunity. Maintain immune homeostasis.
Key Outcome Reduced symptom severity and a shorter illness duration. Reduced frequency of respiratory tract infections, improved digestion.
Duration of Use Shorter course during illness, often continued after symptoms resolve. Consistent, daily intake.
Strain Focus Strains known for specific immunomodulatory effects (e.g., L. rhamnosus GG, L. plantarum). Often a multi-strain approach.

Considerations and Safety Warnings

While probiotics are generally considered safe, there are considerations when you are sick. It is always recommended to consult with a healthcare provider before starting any new supplement, especially if you have a pre-existing medical condition or are on medication. The effectiveness of probiotics is also highly strain-specific and dose-dependent.

Conclusion

Taking probiotics when you are already sick can be a helpful strategy for managing certain conditions. For viral respiratory infections, evidence suggests they may reduce the duration and severity of symptoms by modulating the immune system. In cases of diarrhea, probiotics have a more established role in shortening illness. However, the benefits are not uniform and depend heavily on the specific strain and dosage. The existing evidence indicates a potential benefit, especially for common viral and bacterial infections. Prioritize safety and consult a healthcare professional, particularly if you have a compromised immune system or are dealing with a serious illness. {Link: ScienceDirect https://www.sciencedirect.com/science/article/pii/S0022316622091398}

Authoritative Link

For comprehensive information on the clinical applications of probiotics, consult this resource: Probiotics: What They Are, Benefits & Side Effects - Cleveland Clinic

How Probiotics Interact with the Body During Sickness

  • The gut-associated lymphoid tissue (GALT) houses immune cells critical to overall immune function.
  • Probiotics can enhance immune responses to help fight pathogens.
  • During illness, probiotics may restore gut bacteria balance.
  • Some probiotics can help reduce pain and inflammation.
  • Probiotics can strengthen the intestinal barrier.

Specific Probiotic Strains for Illnesses

  • Certain Lactobacillus and Bifidobacterium strains are studied for shortening cold duration.
  • Saccharomyces boulardii is known for treating diarrhea.
  • Multi-strain formulations may offer broader benefits.

How to Choose a Probiotic When Sick

  • Look for products listing specific strains.
  • Consider a product with a high CFU count, following dosage.
  • Choose a reputable brand.

Probiotics and Diarrhea

  • Probiotics are effective for antibiotic-associated diarrhea.
  • Strains like Lactobacillus rhamnosus GG and Saccharomyces boulardii reduce diarrhea symptoms.
  • Starting probiotics early during diarrhea is crucial, but they can still help if started mid-illness.

Safety Precautions When Using Probiotics During Illness

  • It is important to consult a healthcare provider before taking probiotics, especially for those with compromised immune systems.
  • Mild side effects like gas may occur.
  • Not all probiotic products are FDA regulated.

Frequently Asked Questions

While probiotics don't cure a cold, some studies suggest that certain strains may help reduce the duration and severity of symptoms, potentially shortening the illness by a day or two.

Some well-researched strains for immune support include Lactobacillus rhamnosus GG and certain L. plantarum strains for respiratory infections, and Saccharomyces boulardii for diarrhea.

For most healthy people, taking a probiotic during antibiotic treatment is safe and can help prevent antibiotic-associated diarrhea. It's often recommended to take the probiotic a few hours before or after the antibiotic dose.

The gut-lung axis is the bidirectional communication between the gut and the lungs. Probiotics can modulate the immune response in the gut, which in turn influences immune responses in the respiratory tract, helping to combat respiratory infections.

Antibiotics disrupt the natural balance of gut bacteria, leading to diarrhea. Probiotics introduce beneficial bacteria to replenish the gut, helping to restore balance and reduce diarrhea symptoms.

Yes, fermented foods like yogurt with 'live and active cultures,' kefir, and sauerkraut contain probiotics. However, supplements typically provide a higher, more concentrated dose of specific, clinically studied strains.

Individuals who are seriously ill or immunocompromised should consult a doctor before taking probiotics due to potential risks.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.