What Exactly is Oxidative Stress?
Oxidative stress is an imbalance between free radical production and antioxidant defenses. Free radicals are reactive molecules that damage cellular components like DNA and proteins by stealing electrons. This damage is linked to chronic diseases. Environmental factors can increase free radicals.
The Role of Free Radical Scavenging
A main function of antioxidants is to scavenge and neutralize free radicals by donating an electron, stopping the damage process. Antioxidants remain stable after donating an electron.
Different Antioxidants, Different Mechanisms
Antioxidants work in various ways. Vitamin C is water-soluble, while Vitamin E is fat-soluble, protecting different parts of the cell. Some bind metal ions that promote oxidation. The body uses both internal and dietary antioxidants.
Sources of Antioxidants: Dietary vs. Endogenous
The body has its own defenses and relies on external sources.
- Dietary Antioxidants: Found in foods like fruits and vegetables, including vitamins and phytonutrients. Examples are Vitamin C, Vitamin E, Lycopene, and Flavonoids.
- Endogenous Antioxidants: Produced by the body, such as superoxide dismutase. Diet is important when free radicals overload internal defenses.
Antioxidant Comparison Table: Foods vs. Supplements
Getting antioxidants from whole foods is recommended due to their synergistic effects.
| Feature | Whole Foods (e.g., berries, leafy greens) | Antioxidant Supplements (e.g., Vitamin C tablet) |
|---|---|---|
| Synergy | Complex mix of nutrients working together. | Isolated compounds, often lacking synergy. |
| Effectiveness | Greater antioxidant power compared to isolated supplements. | May lack benefits and can be harmful in high doses. |
| Absorption | Body is designed for efficient absorption from food. | Absorption can be unpredictable. |
| Risk of Overdose | Negligible with a balanced diet. | High doses can act as pro-oxidants. |
| Health Benefits | Linked to reduced risk of many chronic diseases. | Research on disease prevention is inconsistent. |
Specific Functions Beyond Neutralization
Antioxidants have other roles. Vitamin E protects cell membranes, especially in the nervous system. Selenium is vital for antioxidant enzymes. These show the body's multi-layered defense.
Conclusion
The main function of antioxidants is neutralizing free radicals, preventing oxidative stress and cell damage. A diet rich in antioxidant whole foods is essential for defense and contributes to health.