The Resveratrol Content in Mulberry Fruits and Roots
Resveratrol is a natural phenolic compound produced by several plants, including the mulberry tree (Morus genus), in response to stress such as fungal infections or ultraviolet (UV) radiation. Research has revealed that the concentration of this potent antioxidant varies greatly depending on the plant part, species, and environmental conditions.
Quantitative Findings from Scientific Studies
Several studies have quantified the resveratrol content in different parts of the mulberry plant:
- Mulberry Fruit: A study on the whole fruit extract of Red Mulberry (Morus rubra) reported a significant resveratrol concentration of 50.61 µg per gram of dry weight. This is notably higher than the amount found in the seed extracts of grapes within the same study. However, another study on White Mulberry (Morus alba) fruit found a much lower concentration of just 0.48 µg per gram of fresh weight. These findings illustrate the vast differences between species.
- Mulberry Roots: Research has consistently shown that the roots of the mulberry tree contain a far higher concentration of resveratrol than the fruit. A 2021 study on White Mulberry found the roots contained 32.45 µg of resveratrol per gram, which is over 68 times the amount found in the fruit. Another analysis confirmed this, noting that the underground parts of Morus alba contained a higher concentration of resveratrol and oxyresveratrol than the other parts.
- Mulberry Leaves: The leaves are another part of the plant rich in stilbene compounds. A study on wild-type mulberry leaves reported high resveratrol contents, particularly in autumn and in fully matured leaves. Certain varieties showed exceptionally high levels, suggesting the leaves are a valuable source, especially when dried and processed.
Mulberry vs. Grape: A Comparison of Resveratrol Content
When considering resveratrol, grapes and red wine are the most frequently cited sources. However, as the research indicates, mulberries are a competitive source, and in some contexts, a richer one. The following table provides a comparison of resveratrol content based on available research.
| Source | Resveratrol Content (approx.) | Part of Plant | Notes | 
|---|---|---|---|
| Mulberry (Morus rubra) | 50.61 µg/g dry weight | Whole Fruit Extract | Higher than grape seed extract in one study | 
| Mulberry (Morus alba) | 0.48 µg/g fresh weight | Fruit | Varies significantly by species | 
| Mulberry (Morus alba) | 32.45 µg/g | Roots | Found to be a much richer source than the fruit | 
| Mulberry (Morus alba) | Up to 3.45 mg/g dry weight | Leaves | Specific varieties can have high levels | 
| Grape (Vitis vinifera) | 5.89 µg/g dry weight | Seed Extract | Lower than Morus rubra fruit in comparative study | 
| Grape (Vitis vinifera) | 5–10 mg/kg fresh weight | Skins | Content can be increased by environmental stress | 
Factors Influencing Resveratrol Levels
Several intrinsic and extrinsic factors can cause the variability observed in resveratrol concentrations across mulberry plants and products.
- Plant Variety and Species: Different species of mulberry, such as Morus alba (white), Morus rubra (red), and Morus nigra (black), and even different cultivars within the same species, produce varying amounts of resveratrol.
- Environmental Stress: Resveratrol is a phytoalexin, meaning it is produced by the plant as a defense mechanism. Stressors like fungal infection, UV light exposure, or heavy metal ions can trigger increased production.
- Part of the Plant: As highlighted by research, the root and bark often contain significantly higher concentrations of resveratrol and related compounds than the fruit.
- Ripeness and Season: The stage of maturity and the season of harvest can impact resveratrol levels. For instance, mulberry leaves harvested in autumn have been shown to have higher content than those harvested in spring.
- Processing and Preservation: Processing methods, including freeze-drying or specific wine-making techniques, can affect the final resveratrol content. For example, adding mulberry peel during fermentation can increase the resveratrol level in mulberry wine.
The Health Benefits of Mulberry Resveratrol
Like the resveratrol from grapes, the compound found in mulberries is associated with numerous health advantages, largely due to its powerful antioxidant properties.
- Cardiovascular Support: Resveratrol helps promote cardiovascular health by protecting blood vessels, reducing inflammation, and improving circulation.
- Anticancer Properties: Research indicates that mulberry extract, and its resveratrol content, may help inhibit the growth and proliferation of certain cancer cells and induce programmed cell death (apoptosis) in tumors.
- Anti-inflammatory Effects: Mulberries contain natural supporters of a healthy inflammation response in the body, including resveratrol. Chronic inflammation is a contributing factor to many diseases.
- Anti-Aging and Longevity: The antioxidant effects of resveratrol protect cells from oxidative stress and DNA damage, which are key factors in the aging process. This contributes to anti-aging and longevity benefits.
- Blood Sugar Regulation: Some studies suggest that resveratrol and other mulberry compounds can help regulate blood sugar levels, which is beneficial for managing and preventing type 2 diabetes.
Conclusion
While grapes and wine remain popular sources, mulberries are a potent, and often overlooked, dietary source of resveratrol, with concentrations that can exceed those found in grapes depending on the variety and part of the plant. Scientific evidence confirms that the roots and leaves of the mulberry tree are particularly rich in this beneficial compound, though the fruit is still a valuable source, especially certain red mulberry varieties. The amount of resveratrol is highly variable and depends on factors like species, harvest time, and processing. Including mulberries, in their various forms, into your diet can provide a natural and effective way to increase your intake of this powerful antioxidant, contributing to cardiovascular health, anti-inflammatory effects, and other vital functions.
For more detailed information on resveratrol, its mechanisms, and clinical trials, the National Institutes of Health (NIH) is a valuable resource. For instance, this NIH study on antioxidant activity and mechanism of resveratrol from mulberry offers additional scientific insight.