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How to bulk up before chemotherapy: A complete guide

4 min read

According to a 2025 study published in the National Institutes of Health journal, non-small cell lung cancer patients who experienced strategic weight gain before starting chemotherapy showed improved overall and progression-free survival rates. This process, known as prehabilitation, involves building your body's physical and nutritional reserves to better withstand the stresses of treatment.

Quick Summary

Strategic weight gain before chemo, known as prehabilitation, focuses on building physical reserves with high-calorie, protein-rich foods and tailored exercise. This preparation helps the body cope better with treatment side effects like fatigue and nausea, supporting overall strength and recovery.

Key Points

  • Prehabilitation Focus: The goal is to build nutritional and physical reserves, not just muscle mass, to prepare the body for chemotherapy.

  • Nutrient-Dense Foods: Prioritize healthy fats (avocado, olive oil), full-fat dairy, and fortified foods to maximize calories in smaller, more frequent meals.

  • Prioritize Protein: Increase high-quality protein intake from lean meats, fish, eggs, and plant-based sources like beans and tofu to protect muscle mass and support immune function.

  • Moderate Exercise: Incorporate a mix of moderate aerobic activity and light strength training, such as resistance bands or bodyweight exercises, with medical approval.

  • Manage Eating Challenges: Prepare for potential side effects by pre-cooking meals, focusing on hydrating fluids, and consulting with an oncology dietitian.

  • Avoid Risky Foods: Stay away from raw or undercooked foods, unpasteurized products, and communal buffets, especially if you may become immunocompromised.

In This Article

Understanding the 'Bulking Up' Concept for Chemotherapy

For many, the term 'bulking up' evokes images of intense muscle building. For cancer patients, however, it takes on a different meaning: building a foundation of strength and nutritional reserves to endure the rigors of chemotherapy. Chemotherapy is a demanding process that can lead to significant weight and muscle loss, primarily due to side effects like loss of appetite, nausea, and fatigue. Pre-treatment preparation, often called prehabilitation, aims to combat this by boosting physical resilience and overall well-being. Focusing on a nutrient-dense, high-calorie, and high-protein diet, combined with appropriate exercise, can help patients maintain strength and muscle mass, potentially leading to fewer treatment delays and a quicker recovery.

Nutritional Strategies for Building Reserves

Building your body’s reserves before chemotherapy requires a strategic approach to nutrition. The goal is to consume enough calories and protein to gain or maintain weight while focusing on nutrient-dense foods that support immune function and overall health.

High-Calorie and Nutrient-Dense Foods

To increase calorie intake without feeling overwhelmed, focus on foods that pack a lot of energy into a small volume. Small, frequent meals and snacks are often easier to manage than large portions.

  • Healthy Fats: Incorporate high-calorie fats like avocados, olive oil, nuts, and nut butters into your diet. Add a spoonful of peanut butter to your oatmeal or spread it on crackers for a quick, energy-rich snack.
  • Full-Fat Dairy: Opt for full-fat milk, Greek yogurt, and cottage cheese. These provide a good source of protein and calcium. Greek yogurt can be mixed with fruit, nuts, and honey for a calorie-dense treat.
  • Smoothies: A perfect way to 'drink your calories' when appetite is low. Blend full-fat milk or yogurt, nut butter, protein powder, and fruits like bananas and berries for a high-calorie, nutrient-packed beverage.
  • Enriched Foods: Add extra calories and protein to your regular meals by fortifying them. Stir dried milk powder into soups or sauces, top vegetables with cheese or butter, and use cream-based sauces.

Prioritizing Protein Intake

Protein is crucial for repairing tissues and maintaining muscle mass. Adequate protein intake is vital for supporting your immune system and overall strength during and after treatment. The American Cancer Society recommends consuming lean protein sources and plant-based options.

  • Lean Meats and Fish: Examples include chicken, turkey, and fish. Try baking or broiling these protein sources rather than frying.
  • Eggs: A versatile and inexpensive protein source. Hard-boiled eggs are a convenient snack.
  • Plant-Based Proteins: Incorporate beans, lentils, tofu, and nuts. These are rich in protein, fiber, and other nutrients.

Exercise and Physical Activity Before Chemotherapy

Regular physical activity is a cornerstone of prehabilitation. It helps maintain muscle mass, increases energy levels, and can improve mood. However, the approach should be tailored to your current fitness level and health status, always with medical team approval.

  • Moderate Intensity Aerobic Activity: Aim for at least 150 minutes of moderate activity per week, such as brisk walking, swimming, or cycling.
  • Strength Training: Resistance exercises are key for building and maintaining muscle. This can include light weight lifting, resistance bands, or bodyweight exercises like squats and wall push-ups.
  • Flexibility and Balance: Incorporate activities like yoga or Tai Chi twice a week to improve stability and range of motion.

Comparison of Standard Bulking vs. Pre-Chemo Bulking

Feature Standard Bulking Pre-Chemo Bulking Emphasis and Rationale
Protein Sources Any source for maximum intake (e.g., high red meat) Lean meats, plant-based proteins, dairy Focus on high-quality, easily digestible proteins to support muscle and immune system without taxing the body.
Fat Sources Any high-calorie fat for energy (e.g., high-saturated fat) Healthy fats (avocado, olive oil, nuts, seeds) Supports cardiovascular health and provides sustained energy, reducing inflammation.
Exercise Intensity High-intensity weightlifting, heavy loads Moderate-intensity aerobic exercise, light resistance training Builds strength and endurance without causing extreme fatigue or over-stressing the body before treatment.
Dietary Focus Calorie surplus for muscle gain Nutrient density, immune system support, and calorie fortification Maximizes nutritional impact while supporting the body's ability to heal and fight infection.

Managing Common Eating Challenges

Preparing for chemotherapy also involves anticipating potential side effects that can affect appetite and eating. Planning ahead can make it easier to manage nutrition when fatigue or nausea sets in.

  • Stock up on easy-to-prepare meals: Cook and freeze meals in small, individual portions. Stock your pantry with easy-to-digest snacks like crackers, canned fruit, and pudding for days with low energy.
  • Manage changes in taste and smell: Chemotherapy can cause metallic or bitter tastes. Use plastic cutlery, try new spices and marinades, or experiment with tart flavors like lemon or lime.
  • Stay hydrated: Drink plenty of fluids, including water, broth, or electrolyte drinks, between meals to prevent dehydration and help flush chemo byproducts.
  • Consult a dietitian: An oncology dietitian can provide personalized advice and strategies for managing dietary needs and side effects before and during treatment.

Conclusion

Undertaking a strategic pre-chemotherapy 'bulking up' plan is a proactive step that can significantly improve a patient's treatment tolerance and recovery. It’s not about lifting the heaviest weights but about building a robust nutritional and physical foundation. By focusing on a high-calorie, high-protein diet rich in healthy fats and nutrients, combined with a consistent and moderate exercise routine, patients can enter treatment with greater strength and resilience. Advanced preparation, such as pre-cooking meals and consulting with a specialized oncology dietitian, further empowers patients to manage potential side effects and maintain a better quality of life. This intentional preparation can make a profound difference in a patient's chemotherapy journey. For more guidance on boosting your caloric intake, Roswell Park Cancer Center offers more tips on increasing calorie intake.

Frequently Asked Questions

Yes, but it must be done under the guidance of your medical team, including a dietitian. Strategic weight gain, known as prehabilitation, can help build physical reserves and improve your body's ability to tolerate treatment.

It is best to start as soon as you receive your diagnosis and treatment plan. Studies show that even a few weeks of prehabilitation can improve fitness and build muscle, providing benefits before treatment begins.

Focus on foods like eggs, fish, lean meats, beans, lentils, tofu, nuts, and full-fat dairy products. Using nut butters, avocados, and oils can also boost calorie intake easily.

A combination of moderate aerobic activity, like brisk walking or swimming, and light strength training is recommended. This could involve using light weights, resistance bands, or bodyweight exercises.

It is common to lose your appetite. The key is to eat small, frequent, and nutrient-dense meals and snacks throughout the day, rather than three large ones. Consider high-calorie smoothies and keep easy-to-eat foods readily available.

Supplements should only be taken with the approval of your doctor or oncology dietitian. While meal replacement shakes can be helpful, especially homemade ones, it is important to ensure they don't interfere with your treatment plan.

Planning ahead is key. Pre-cook and freeze meals, stock up on bland, easy-to-digest snacks, and identify flavors or smells that might trigger nausea. Consulting with a dietitian can also provide personalized strategies.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.