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How to Reduce Histamine in Wine for Healthier Sipping

5 min read

An estimated 1-3% of the population suffers from some form of histamine intolerance, experiencing symptoms like flushing or headaches after drinking wine. Learning how to reduce histamine in wine can be a game-changer for sensitive individuals who want to enjoy their favorite beverages without the unwelcome side effects.

Quick Summary

This guide outlines how to reduce histamine in wine by choosing naturally low-histamine varieties, identifying beneficial winemaking techniques, and utilizing practical at-home purification tools. It details how fermentation processes, aging, and grape type impact histamine levels, providing actionable tips for sensitive drinkers.

Key Points

  • Choose White or Rosé: These wines generally have lower histamine levels than red wines due to less skin contact and fermentation.

  • Select Young Wines: Histamine levels can increase during aging, so opt for younger, fresher wines for lower histamine content.

  • Filter Your Wine: Use in-glass purification tools, such as adsorptive filters, to actively reduce histamines and other irritants in any glass of wine.

  • Look for Low-Histamine Production: Seek out winemakers who use stainless steel fermentation and carefully controlled yeast cultures to minimize histamine formation.

  • Be Aware of Food Pairings: Certain foods, such as aged cheeses, can also be high in histamine. Be mindful of food and wine combinations to avoid a combined effect.

  • Manage Your Fermentation: Winemaking methods that skip or strictly control malolactic fermentation result in lower histamine levels.

In This Article

Understanding Histamine in Wine

Histamine is a natural compound present in many fermented foods and beverages, including wine. It is a byproduct of the fermentation process, primarily produced by certain bacteria that convert the amino acid histidine into histamine. While harmless to most, individuals with histamine intolerance lack sufficient diamine oxidase (DAO) enzymes to break down this histamine, leading to an inflammatory response. This can manifest as headaches, skin flushing, nasal congestion, or a racing heart. The amount of histamine in wine varies drastically, depending on several key factors in the winemaking process.

The Impact of Grapes and Winemaking on Histamine

Different grape varieties and production methods significantly influence the final histamine content. Red wines are typically much higher in histamine than white wines due to prolonged contact with grape skins during fermentation, as grape skins contain abundant histidine. Additionally, malolactic fermentation (MLF), a secondary fermentation that gives red wines a smoother, softer flavor, is a major source of histamine production. Winemakers who control these factors can produce naturally lower-histamine wines.

Practical Strategies for Reducing Wine Histamine

For those sensitive to histamine, several strategies can help minimize adverse reactions. The first involves being selective about the wine you choose, while the second utilizes post-pour purification methods.

Choosing the Right Wine

  • Opt for young, dry whites: White wines and rosés have less contact with grape skins and often skip malolactic fermentation, resulting in much lower histamine levels. Look for young, fresh wines, as histamine can accumulate during aging.
  • Seek out specific low-histamine labels: Some European winemakers produce certified low-histamine wines, often advertising or certifying their product contains less than 0.5 mg/L of histamine. These wines are lab-tested and crafted under hygienic conditions to prevent histamine formation.
  • Select favorable grapes: Thick-skinned red grapes like Cabernet Sauvignon tend to produce wines with higher histamine. Lighter, thinner-skinned red varieties like Pinot Noir, especially if made with minimal intervention, can be a better option.

Active Reduction with Filtration

For those who don't want to rely solely on specialty wines, in-glass purification tools can actively remove histamine and other irritants. Products like ALKAA, PureWine's The Wand, or The Phoenix use adsorptive filters to bind with compounds in the wine, effectively reducing histamine levels.

List of Low-Histamine Winemaking Methods

  • Stainless steel fermentation: Using stainless steel tanks instead of porous wooden barrels allows for easier sterilization and better temperature control, limiting unwanted bacterial growth.
  • Controlled fermentation cultures: Winemakers can select specific yeast and bacterial strains that produce less histamine during fermentation.
  • Early skin removal: For red wines, limiting the duration of skin contact during fermentation reduces the initial concentration of histidine, the precursor to histamine.
  • Minimal or no malolactic fermentation: Controlling or skipping this secondary fermentation process is a critical step in lowering histamine levels, especially in white and some red wines.
  • Low-nitrogen soils: Some producers intentionally refrain from nitrogen fertilization to keep nitrogen levels in grapes low, which helps minimize histamine formation.

Comparison of Wine Types for Histamine Sensitivity

Feature Red Wine (e.g., Cabernet Sauvignon) White Wine (e.g., Sauvignon Blanc) Filtered Wine (Any Type)
Histamine Level High (can be 20-200% higher than whites) Low to Moderate Significantly Reduced
Skin Contact Extensive Minimal or none Varies; filtered post-fermentation
Malolactic Fermentation Common; increases histamine Often avoided; lower histamine Varies; filtration addresses post-fermentation
Ideal for Sensitive Drinkers? No, typically the riskiest choice Yes, generally safer Yes, provides the most control
Impact on Flavor Full-bodied, complex; filtration has no impact Crisp, fresh; no impact from filtration None; removes irritants without altering taste

Conclusion

While a completely histamine-free wine is not possible, sensitive drinkers can effectively manage their intake by understanding the factors that influence histamine content. From choosing naturally lower-histamine varieties like fresh white wines to employing in-glass purification tools, there are several viable strategies. Combining these approaches empowers you to enjoy wine without the unpleasant side effects of histamine sensitivity. By being mindful of winemaking processes and using modern technology, you can reclaim the pleasure of a glass of wine. For more in-depth research on the compounds that cause wine sensitivity, refer to studies cited by authoritative sources.

Visit ALKAA for more information on active wine purification tools

Frequently Asked Questions

Can you really filter histamine out of wine?

Yes, modern purification tools, such as adsorptive filters placed directly in your glass, can effectively reduce histamines and other irritants like sulfites and tannins without altering the wine's taste or aroma. These products work by binding to unwanted compounds, leaving the wine's flavor profile intact.

What type of wine is lowest in histamine?

Generally, young, dry white wines and rosés have the lowest histamine levels because they have less contact with grape skins and often do not undergo malolactic fermentation. Lighter red wines like Pinot Noir, especially if minimally processed, can also be a better option than heavy reds.

Does aging a wine affect its histamine content?

Yes, histamine levels typically increase during a wine's storage and aging process. For those sensitive to histamine, fresher, younger wines are often a safer choice compared to older, more complex bottles.

What role do winemaking practices play in histamine reduction?

Winemaking practices are crucial. Using stainless steel tanks, carefully selected yeast and bacterial cultures, and limiting skin contact all help minimize histamine production. Some winemakers even specialize in creating certified low-histamine wines by meticulously controlling these processes.

Is organic wine always low in histamine?

No, organic wine is not automatically low in histamine. The organic label refers to how the grapes are grown (without synthetic pesticides), not how the wine is fermented. Since histamine is a natural byproduct of fermentation, an organic red wine can still be high in histamine.

How can a histamine-sensitive person choose wine in a restaurant?

In a restaurant, opt for a glass of young, dry white wine or rosé from a reputable producer. If you are concerned about a reaction, you can discreetly use a personal wine purifier tool to treat your wine in the glass, reducing histamines on the spot.

Are histamine headaches from wine the same as sulfite headaches?

No, they are different, though the symptoms can overlap. Sulfites are a preservative that triggers asthma-like or other allergic reactions in some people. Histamines, produced during fermentation, trigger a different inflammatory response in those with histamine intolerance. It's possible to react to both, but they are distinct issues. Many sensitive individuals find relief by addressing both histamine and sulfite levels.

Frequently Asked Questions

Yes, red wine typically has significantly higher histamine levels than white wine because the winemaking process for reds involves longer contact with grape skins, where histamine precursors are abundant, and often includes malolactic fermentation, which produces histamine.

No wine is completely histamine-free, as histamines are a natural byproduct of fermentation and cannot be fully filtered out. However, specialty "low-histamine" wines contain extremely low, lab-tested levels, making them a suitable option for sensitive individuals.

Wine purification tools typically use an adsorptive filter technology. When placed in a glass, a filter attracts and binds to undesirable compounds like histamines and sulfites, removing them from the beverage without changing the wine's intrinsic taste, aroma, or alcohol content.

Winemakers can reduce histamine by using hygienic stainless steel fermentation tanks, selecting low-histamine-producing yeast and bacterial cultures, and avoiding or controlling malolactic fermentation. Limiting skin contact, especially with thick-skinned grapes, is also key.

Yes, these are distinct sensitivities. Sulfites are a preservative that can trigger allergic-like reactions, while histamines are a byproduct of fermentation that can cause intolerance symptoms. While many people react to both, addressing histamine and sulfite levels can offer relief.

Yes, but with precautions. You can choose lighter red varieties like Pinot Noir, drink young wines instead of aged ones, and use an in-glass purifier to reduce histamine content on the spot. Pairing it with low-histamine foods is also recommended.

In addition to aged wines, many fermented foods like aged cheeses and cured meats are high in histamine. To minimize total histamine load, it's wise to limit these pairings, especially when drinking wine.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.