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Is MSG good in moderation? The complete guide to this misunderstood food additive

4 min read

According to the U.S. Food and Drug Administration (FDA), MSG is classified as “Generally Recognized as Safe” (GRAS) when used at normal dietary levels. However, decades of misinformation have led many people to still question: Is MSG good in moderation?.

Quick Summary

Decades of research show MSG is safe for most individuals when consumed in typical dietary amounts. It can also help reduce overall sodium intake without sacrificing flavor, though some sensitive individuals may experience mild, temporary symptoms.

Key Points

  • Safety Consensus: MSG is considered safe for most people by major health organizations like the FDA and WHO when consumed in typical amounts.

  • Natural vs. Added Glutamate: The human body processes the glutamate in MSG identically to glutamate that occurs naturally in foods like cheese and tomatoes.

  • Myth Busting: The 'Chinese Restaurant Syndrome' is a myth based on outdated, poorly-designed studies and racial bias, not sound science.

  • Low Sodium Alternative: MSG contains significantly less sodium than table salt, offering a way to reduce sodium intake while maintaining flavor.

  • Mild Sensitivity: Fewer than 1% of people may experience mild, short-term symptoms only when consuming very large doses (>3g) of MSG on an empty stomach.

  • Flavor Enhancer: MSG is the purest form of umami, the fifth basic taste, and can enhance the savory flavor of many different dishes.

In This Article

What Exactly is MSG?

Monosodium glutamate, or MSG, is the sodium salt of glutamic acid, one of the most common amino acids. Glutamate is found naturally in many foods we eat daily, such as aged cheeses, tomatoes, and mushrooms. It provides the savory, or umami, flavor that enhances and deepens the taste of food. The MSG that is added to food as a seasoning is produced through a fermentation process, similar to making yogurt or vinegar, using plant-based sources like sugar cane or molasses.

Debunking the Myths: Separating Fact from Fiction

For decades, MSG has been shrouded in controversy, largely stemming from a single letter written to a medical journal in 1968 that described symptoms experienced after eating Chinese food. This letter led to the racist and now-discredited term “Chinese Restaurant Syndrome.” Subsequent, poorly-designed studies in animals using unrealistic, high doses of MSG administered via injection further fueled this misinformation. Modern, well-controlled human studies have largely debunked these claims.

The Science Behind MSG Safety

Multiple major health authorities have evaluated MSG and confirmed its safety for the general population. This includes the U.S. Food and Drug Administration (FDA), the Joint FAO/WHO Expert Committee on Food Additives (JECFA), and the European Food Safety Authority (EFSA).

  • Body Metabolism: The body processes glutamate from MSG in the same way as glutamate found naturally in other foods. The body is highly efficient at regulating glutamate levels, preventing harmful excess from dietary intake.
  • Dietary Intake vs. High Doses: The mild, temporary symptoms reported by a very small percentage of the population (less than 1%) typically only occur with extremely high doses (3 grams or more) of MSG consumed on an empty stomach. A typical serving of food with added MSG contains less than 0.5 grams.
  • No Long-Term Health Risks: Extensive research has found no evidence linking normal MSG consumption to long-term medical issues such as obesity, metabolic disorders, or neurological damage.

A Comparison: MSG vs. Table Salt

While both MSG and table salt contain sodium and enhance flavor, they do so differently and with varying sodium content. This makes MSG a useful tool for sodium reduction.

Feature MSG (Monosodium Glutamate) Table Salt (Sodium Chloride)
Primary Function Enhances umami, boosting savory flavors. Provides saltiness, a fundamental taste.
Sodium Content Approximately 12% sodium by weight. Approximately 39% sodium by weight.
Flavor Profile Subtly enhances existing savory flavors without overpowering them. Strong, direct salty flavor. Too much can ruin a dish.
Benefits Can be used to reduce overall sodium in dishes while maintaining flavor perception. Preservative, flavor agent, and texture enhancer.
Health Authorities Deemed safe by FDA, WHO, EFSA. Excessive intake is a major contributor to health issues like hypertension.

Potential Benefits and Applications of MSG

Beyond flavor enhancement, using MSG in moderation offers some practical benefits, particularly in a health-conscious context.

List of MSG benefits:

  • Sodium Reduction: Replacing some salt with MSG can lower the sodium content of a dish by up to 40% without losing flavor. This can be particularly helpful for individuals with hypertension or those on a low-sodium diet.
  • Improving Palatability: As we age, our sense of taste and smell can diminish. Adding MSG can improve the palatability and acceptance of food for the elderly, which can be crucial for maintaining a healthy diet.
  • Enhancing Plant-Based Dishes: MSG can intensify the umami taste in vegetarian and vegan dishes, making them more satisfying and flavorful. It is often used in vegetable-based broths, soups, and sauces.
  • Appetite Regulation: Some animal studies and human trials have shown that MSG-enhanced foods might increase feelings of fullness, potentially helping with appetite control, though more research is needed.

How to Use MSG in Moderation

Using MSG is simple and a little goes a long way. It’s a self-limiting ingredient; adding too much actually decreases the food's palatability, which naturally prevents overconsumption. It can be added to dishes like soups, stews, sauces, and casseroles. For home cooking, start with a small pinch and adjust to taste, much like you would with salt. It can also be mixed with salt in a 1:1 ratio for an effective low-sodium seasoning blend. For more cooking ideas, you can explore resources like the one from Harvard Health.

Conclusion: The Bottom Line on MSG

The scientific consensus is clear: for the vast majority of the population, MSG is safe when consumed in moderation as part of a normal diet. The fears surrounding MSG are largely based on outdated and flawed studies, as well as cultural bias. The glutamate in MSG is chemically identical to the glutamate found naturally in many whole foods and is metabolized in the same way by the body. In fact, far from being harmful, MSG offers a practical and effective way to reduce overall sodium intake without sacrificing delicious flavor. While a very small subset of individuals may have a sensitivity to large doses, this is not indicative of a widespread health risk. For most people, MSG is a valuable culinary tool to be enjoyed responsibly.

Frequently Asked Questions

Controlled studies have not been able to consistently link normal MSG consumption to headaches or other symptoms. Mild, temporary symptoms are only reported in a very small number of people when consuming very large amounts without food.

No. The human body metabolizes the glutamate from natural sources and the glutamate from added MSG in the exact same way. There is no chemical distinction between them once they are digested.

Yes. MSG contains roughly one-third the amount of sodium as table salt. Replacing some salt with MSG can lower the sodium content of a dish by up to 40% while maintaining flavor.

Yes, major health organizations have confirmed MSG's safety for the general population, including children, at typical dietary levels. Some older, flawed studies suggested sensitivity in children, but this has not been substantiated by modern research.

Foods with added MSG must be labeled as 'monosodium glutamate.' However, many foods contain naturally-occurring glutamate, such as yeast extract or soy protein, and these do not have to be explicitly labeled as containing MSG.

The average person consumes less than one gram of added MSG daily, far below the threshold (3 grams or more) that might cause mild, temporary symptoms in sensitive individuals.

Current research does not provide compelling evidence linking MSG intake to obesity or weight gain. Some contradictory animal and epidemiological studies exist, but they do not prove a causal relationship in humans.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.