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Is Stevia a Glycoside? Understanding the Sweetener's Chemistry

3 min read

Derived from the leaves of the Stevia rebaudiana plant, stevia is approximately 200-400 times sweeter than regular table sugar. It is not a single compound but rather a collection of sweet-tasting chemicals, which are indeed a type of glycoside. The specific group of compounds responsible for stevia's sweetness is known as steviol glycosides.

Quick Summary

This article explores the chemistry of stevia, clarifying that it is comprised of steviol glycosides, the specific molecules that produce its intense sweetness and zero-calorie status. It details the most common types of steviol glycosides, their properties, and how they interact with taste receptors.

Key Points

  • Yes, Stevia is a Glycoside: Specifically, stevia's sweet compounds are called steviol glycosides, molecules where sugar units are attached to a non-sugar base.

  • Zero-Calorie Sweetness: Steviol glycosides are not metabolized for energy, allowing them to provide sweetness without contributing calories.

  • Different Types of Glycosides: The stevia plant contains over 30 different steviol glycosides, with stevioside and rebaudioside A being the most common.

  • Taste Profile Varies: The specific type of glycoside and the purity of the extract influence the final taste, which can range from a clean sweetness to one with a slight aftertaste.

  • Refinement Improves Quality: Modern stevia products use highly purified extracts, often enriched in specific glycosides like Reb A and Reb M, to achieve a more sugar-like flavor.

  • Safe for Consumption: Extensive research and regulatory approval by bodies like the FDA and JECFA support the safety of high-purity steviol glycosides within acceptable daily intake levels.

  • Digestive Pathway: The glycosides travel through the digestive system and are broken down in the colon, where the sugar units are removed, and the non-caloric steviol is excreted.

In This Article

What Exactly Is a Glycoside?

To understand why stevia is a glycoside, it's essential to define what a glycoside is. In chemistry, a glycoside is a molecule in which a sugar is bonded to another non-carbohydrate component. The sugar part is called the 'glycone,' and the non-sugar part is the 'aglycone.' In the case of stevia, the aglycone is a compound called steviol, which is a diterpene. The various sweet compounds found in stevia, known as steviol glycosides, all share this steviol core but have different sugar molecules attached to them, giving each a slightly different taste profile and intensity.

The Specific Glycosides of Stevia

The Stevia rebaudiana plant produces over 30 different steviol glycosides, with varying concentrations. The most prominent and commercially important ones are stevioside and rebaudioside A, but many others exist in smaller amounts.

List of Key Steviol Glycosides:

  • Stevioside: One of the most abundant glycosides, known for its potency, but sometimes associated with a lingering aftertaste.
  • Rebaudioside A (Reb A): Highly prized for its superior taste profile with less bitterness than stevioside, it is a primary ingredient in many modern stevia sweeteners.
  • Rebaudioside M (Reb M): Found in smaller quantities in the plant but is increasingly produced through biotechnology due to its very clean, sugar-like taste.
  • Rebaudioside D (Reb D): Another high-quality glycoside with a clean taste that is produced commercially through extraction and enzymatic conversion.
  • Steviolbioside, Rebaudioside C, and Dulcoside A: These are other glycosides present in lesser concentrations in the stevia leaf.

How Steviol Glycosides Work in the Body

When steviol glycosides are consumed, they are not metabolized in the body in the same way as sugar. They pass through the upper gastrointestinal tract undigested. It is in the colon that intestinal bacteria break down the glycosides, cleaving the sugar units from the steviol backbone. The steviol is then absorbed and metabolized by the liver, but the body does not use it for energy, which is why stevia sweeteners contain zero calories. This unique metabolic pathway makes stevia a suitable alternative for individuals managing their calorie or carbohydrate intake, such as those with diabetes.

A Comparison of Stevia and Sugar

Feature Stevia (Purified Steviol Glycosides) Sugar (Sucrose)
Chemical Type Glycoside Carbohydrate (Disaccharide)
Source Stevia rebaudiana plant Sugarcane or sugar beets
Calories Zero 4 calories per gram
Glycemic Index Impact None High
Sweetness Intensity 200-400 times sweeter than sugar Baseline for comparison (1x)
Taste Profile Sweet with potential lingering aftertaste in less pure forms Pure sweetness
Metabolism Not metabolized for energy; passes through GI tract largely intact Quickly metabolized for energy; raises blood glucose
Heat Stability Highly stable Breaks down at high temperatures (caramelizes)

Refining Process and Product Differences

The term "stevia" on a product label can be misleading, as it often refers to a highly refined steviol glycoside extract rather than the raw leaf. The bitter or licorice-like aftertaste sometimes associated with earlier stevia products came from less refined extracts, particularly those high in stevioside. Modern processing techniques, including enzymatic modification, have allowed for the isolation of specific glycosides like Rebaudioside A and M, which have a cleaner, more sugar-like taste. This refinement explains the variety in taste and quality among different stevia-based products on the market.

Conclusion

In summary, the answer to the question, "Is stevia a glycoside?" is a definitive yes. The sweetness of stevia comes from a family of chemical compounds known as steviol glycosides, extracted from the leaves of the Stevia rebaudiana plant. These compounds, which consist of a non-sugar steviol molecule bonded to sugar units, are not metabolized for energy, making them a popular zero-calorie sweetener. Understanding this fundamental chemical characteristic explains why stevia offers a sweet taste without the caloric impact of sugar. The ongoing refinement of extraction and enzymatic modification processes continues to improve the taste quality of stevia-based products, cementing its place as a leading natural, high-intensity sweetener.

Visit the Food Standards Australia New Zealand website to see their regulations on steviol glycosides (960) as an intense sweetener.

Frequently Asked Questions

While the stevia plant contains several glycosides, the two primary ones found in highest concentration are stevioside and rebaudioside A (Reb A).

Less refined stevia extracts, which contain higher levels of certain glycosides like stevioside, can have a noticeable bitter or licorice-like aftertaste. High-purity extracts, particularly those rich in rebaudioside A and M, have a cleaner, more sugar-like flavor.

Steviol glycosides are not carbohydrates. They are metabolized differently by the body, providing a sweet taste without contributing calories or affecting blood sugar levels, unlike sucrose.

In many countries, including the U.S., only highly purified steviol glycoside extracts are approved as food additives. The use of crude stevia leaf or minimally processed extracts is not approved due to incomplete toxicological information.

Stevia refers to the plant itself, Stevia rebaudiana. Steviol glycosides are the sweet-tasting chemical compounds extracted and purified from the stevia plant's leaves and used in commercial sweeteners.

Numerous regulatory bodies, including the FDA and JECFA, have deemed highly purified steviol glycosides to be safe for consumption within acceptable daily intake levels.

No, because humans cannot metabolize steviol glycosides for energy, they do not induce a glycemic response and therefore do not raise blood sugar levels.

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.